Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Luisa E. Brighton"'
Autor:
Luisa E. Brighton, Katherine T. Mills, Jing Zhang, Haibo Zhou, Michelle L. Hernandez, Ilona Jaspers, Milan J. Hazucha, Johnny L. Carson
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 54(3)
The diversity and extent of signaling functions of nitric oxide (NO) in cell physiology as well as its presence and influence as a common component of ambient air pollution and tobacco smoke are gaining increasing research attention relative to both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada130ed7d75cabe17d6825f1efca738
https://pubmed.ncbi.nlm.nih.gov/29380192
https://pubmed.ncbi.nlm.nih.gov/29380192
Autor:
Laura Zhou, Luisa E. Brighton, Haibo Zhou, Katherine H. Mills, Ilona Jaspers, Milan J. Hazucha, Johnny L. Carson
Mucociliary clearance sustains a baseline functionality and an "on demand" capability to upregulate clearance upon irritant exposure involving mucus hypersecretion and accelerated ciliary beat frequency (CBF) modulated by nitric oxide (NO). This stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16797034f9c8b1e3a4cce2dcb8967034
Autor:
Rebecca N. Bauer, Elizabeth Thompson, Megan Meyer, Rosalia C. M. Simmen, Luisa E. Brighton, James C. Bonner, Ilona Jaspers, Blanche D. Letang
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 306:L269-L276
A hallmark of cigarette smoking is a shift in the protease/antiprotease balance, in favor of protease activity. However, it has recently been shown that smokers have increased expression of a key antiprotease, secretory leukoprotease inhibitor (SLPI)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d44b8a500b07088cca2fab5f6a485f
https://doi.org/10.1152/ajplung.00290.2013
https://doi.org/10.1152/ajplung.00290.2013
Autor:
Robert Silbajoris, James M. Samet, Luisa E. Brighton, Haiyan Tong, Andres R. Henriquez, Steven O. Simmons, Adam M. Speen, Phillip A. Wages, Philip A. Bromberg
Publikováno v:
Redox Biology, Vol 3, Iss C, Pp 47-55 (2014)
Redox Biology
Redox Biology
Human exposure to particulate matter (PM) is a global environmental health concern. Zinc (Zn2+) is a ubiquitous respiratory toxicant that has been associated with PM health effects. However, the molecular mechanism of Zn2+ toxicity is not fully under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77e02be2b3f535758650edbaf3bccd8
http://www.sciencedirect.com/science/article/pii/S2213231714001116
http://www.sciencedirect.com/science/article/pii/S2213231714001116
Autor:
Ilona Jaspers, Lisa Smeester, Luisa E. Brighton, Rebecca C. Fry, Loretta Müller, Johnny L. Carson, Julia E. Rager, Rebecca N. Bauer
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 305:L432-L438
We previously demonstrated that, in nasal epithelial cells (NECs) from smokers, methylation of an antiviral gene was associated with impaired antiviral defense responses. To expand these findings and better understand biological mechanisms underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3707233d4b1ddbda2b47397a646c2be2
https://doi.org/10.1152/ajplung.00116.2013
https://doi.org/10.1152/ajplung.00116.2013
Autor:
Nelia A. Tobey, John L. Carson, Roy C. Orlando, Todd M. Gambling, Luisa E. Brighton, Zorka Djukic
Publikováno v:
Digestive Diseases and Sciences. 55:1856-1865
The structures that contribute to shunt resistance (Rs) in esophageal epithelium are incompletely understood, with 35-40% of Rs known to be calcium-dependent, reflecting the role of e-cadherin. Two calcium-independent candidates for the remaining app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2b4d408440be1ae9632b4a1c0ad57d
https://doi.org/10.1007/s10620-010-1215-4
https://doi.org/10.1007/s10620-010-1215-4
Autor:
Luisa E. Brighton, Milan J. Hazucha, Haibo Zhou, Tsui Shan Lu, Johnny L. Carson, Ilona Jaspers
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 46:606-612
The emergence of air-liquid interface (ALI) culturing of mammalian airway epithelium is a recent innovation for experimental modeling of airway epithelial development, function, and pathogenic mechanisms associated with infectious agent and irritant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9535ab8294435bce9b4e15b41db4460
https://doi.org/10.1007/s11626-010-9310-6
https://doi.org/10.1007/s11626-010-9310-6
Publikováno v:
Microscopy Research and Technique. 73:579-582
Macrophages from smokers demonstrate an increased auto-fluorescence. Similarly, auto-fluorescence follows in vitro exposure of macrophages to cigarette smoke condensate (i.e., the particulate fraction of cigarette smoke). The composition of particles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ae1bc70f877a4cbe72b1db8684cd51
https://doi.org/10.1002/jemt.20804
https://doi.org/10.1002/jemt.20804
Publikováno v:
Journal of Interferon & Cytokine Research. 29:289-297
Previous studies have shown that influenza infections increase Toll-like receptor 3 (TLR3) expression and that type I interferons (IFNs) may play a role in this response. This study aimed to expand on the role of type I IFNs in the influenza-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9368351f9db08929933a37643f3d9e0b
https://doi.org/10.1089/jir.2008.0075
https://doi.org/10.1089/jir.2008.0075
The initial innate immune response to ozone (O3) in the lung is orchestrated by structural cells, such as epithelial cells, and resident immune cells, such as airway macrophages (Macs). We developed an epithelial cell–Mac coculture model to investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3dbbb15b07166444643a6bb44facaa
https://europepmc.org/articles/PMC4370258/
https://europepmc.org/articles/PMC4370258/