Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Luisa C Hernández-Kelly"'
Publikováno v:
ASN Neuro, Vol 14 (2022)
Manganese (Mn) exerts serious neurotoxic effects, among which, the disruption of the glutamate/glutamine (Glu/Gln) cycle, leads to an excitotoxic insult. The molecular mechanisms mediating Mn-induced neurotoxicity, have not yet been fully understood.
Externí odkaz:
https://doaj.org/article/29ad75bcb6cc4fbd90c6cc26a5bc36c3
Autor:
María I. Martínez-Hernández, Leonor C. Acosta-Saavedra, Luisa C. Hernández-Kelly, Jaqueline Loaeza-Loaeza, Arturo Ortega
Publikováno v:
BioMed Research International. 2023:1-27
Neurodegenerative processes encompass a large variety of diseases with different pathological patterns and clinical features, such as Alzheimer’s and Parkinson’s diseases. Exposure to metals has been hypothesized to increase oxidative stress in b
Publikováno v:
Molecular Neurobiology. 59:1912-1924
Publikováno v:
Neurotoxicity Research. 39:2154-2174
The blood–brain barrier is a dynamic structure, collectively referred to as the neurovascular unit. It is responsible for the exchange of blood, oxygen, ions, and other molecules between the peripheral circulation and the brain compartment. It is t
Autor:
Arturo Ortega, Tatiana N. Olivares-Bañuelos, Ana Laura García-López, Luisa C. Hernández-Kelly, Jeanett Hernández-Castillo
Publikováno v:
Neurotoxicity Research. 38:765-774
Fluoride, a pollutant present in contaminated ground water, oral care products, food, and pesticides, has deleterious effects in the structure and function of the central nervous system. Among the established neurological defects described in the exp
Exposure to xenobiotics has a significant impact in brain physiology, that could be liked to an excitotoxic processes induced by a massive release of the main excitatory neurotransmitter, L-glutamate. Overstimulation of post-synaptic and extra-synapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::311a38faeec9dfb7632c59ec8b2aee64
https://doi.org/10.21203/rs.3.rs-824210/v1
https://doi.org/10.21203/rs.3.rs-824210/v1
Autor:
Donají Chi-Castañeda, Luisa C. Hernández-Kelly, Tatiana N. Olivares-Bañuelos, Isabel Martínez-Hernández, Libia Vega, Arturo Ortega
Publikováno v:
Neurochemistry International. 123:77-84
Glutamate, the main excitatory neurotransmitter in the vertebrate Central Nervous System, is involved in almost every aspect of brain physiology, and its signaling properties are severely affected in most neurodegenerative diseases. This neurotransmi
Publikováno v:
Neurotoxicity research. 39(6)
The blood-brain barrier is a dynamic structure, collectively referred to as the neurovascular unit. It is responsible for the exchange of blood, oxygen, ions, and other molecules between the peripheral circulation and the brain compartment. It is the
Autor:
Arturo Ortega, Catya Jiménez-Torres, Hoda El-Kehdy, Mustapha Najimi, Luisa C. Hernández-Kelly, Etienne Sokal
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol. 14, p. 613225 [1-15] (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol. 14, p. 613225 [1-15] (2021)
Glutamate is the main excitatory amino acid acting at the level of pre and postsynaptic neurons, as well as in glial cells. It is involved in the coordinated modulation of energy metabolism, glutamine synthesis, and ammonia detoxification. The relati
Publikováno v:
Journal of neurochemistryREFERENCES. 155(6)
Neurodegenerative diseases are a worldwide health problem and are a major cause of death and disability. A progressive loss of defined neuronal populations is triggered by a diverse array of stimuli that converge in deficient neurotrophic signaling.