Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Luisa A. DiPietro"'
Autor:
Chen Han, Trevor R. Leonardo, Bruna Romana-Souza, Junhe Shi, Shalyn Keiser, Heidi Yuan, Mohamad Altakriti, Matthew J. Ranzer, Sammy Ferri-Borgogno, Samuel C. Mok, Timothy J. Koh, Seok Jong Hong, Lin Chen, Luisa A. DiPietro
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Many factors regulate scar formation, which yields a modified extracellular matrix (ECM). Among ECM components, microfibril-associated proteins have been minimally explored in the context of skin wound repair. Microfibril-associated protein
Externí odkaz:
https://doaj.org/article/7c7ecca738294348a17fd297d13bd8c0
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Chronic, non-healing skin wounds such as diabetic foot ulcers (DFUs) are common in patients with type 2 diabetes mellitus (T2DM) and often result in limb amputation and even death. However, mechanisms by which T2DM and inflammation nega
Externí odkaz:
https://doaj.org/article/4593eac5b8344f379f94b72e6979d82a
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101727- (2022)
Summary: The oral cavity is a highly regenerative epithelial tissue that results in minimal scarring after injury. This protocol describes the preparation of a mouse palate wound model. The protocol includes steps to place an excisional wound on the
Externí odkaz:
https://doaj.org/article/ab4f2df5815240dfa01614e6fa4f3d68
Autor:
Chun-Chieh Huang, Miya Kang, Raghuvaran Narayanan, Luisa A. DiPietro, Lyndon F. Cooper, Praveen Gajendrareddy, Sriram Ravindran
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Mesenchymal stem cells (MSCs) are multipotent cells with regenerative and immunomodulatory properties. Several aspects of MSC function have been attributed to the paracrine effects of MSC derived extracellular vesicles (EVs). Although MSC EVs show gr
Externí odkaz:
https://doaj.org/article/a9f8ec6b2d424a1891e109538aa61e43
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Pathological scarring in wounds is a prevalent clinical outcome with limited prognostic options. The objective of this study was to investigate whether cellular signaling proteins could be used as prognostic biomarkers of patholog
Externí odkaz:
https://doaj.org/article/fe4e82ee0c04494194403e53adceecbe
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Impaired angiogenesis is a hallmark of wounds with delayed healing, and currently used therapies to restore angiogenesis have limited efficacy. Here, we employ a computational simulation-based approach to identify influential molecular and cellular p
Externí odkaz:
https://doaj.org/article/3ad8108a25004facae08cd0a35b3baef
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 950 (2021)
Macrophages are prominent cells in normally healing adult skin wounds, yet their exact functions and functional significance to healing outcomes remain enigmatic. Many functional attributes are ascribed to wound macrophages, including host defense an
Externí odkaz:
https://doaj.org/article/8e71f87265d74449abe50ed3dcc2cbb4
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 521 (2020)
The oral mucosa exhibits exceptional healing capability when compared to skin. Recent studies suggest that intrinsic differences in coding genes and regulatory small non-coding RNA (sncRNA) genes (e.g., microRNAs) may underlie the exceptional healing
Externí odkaz:
https://doaj.org/article/4e324d58093c47acad6a8fd3e8dd8370
Autor:
Lin Chen, Alyne Simões, Zujian Chen, Yan Zhao, Xinming Wu, Yang Dai, Luisa A. DiPietro, Xiaofeng Zhou
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 15, p 3679 (2019)
Wounds within the oral mucosa are known to heal more rapidly than skin wounds. Recent studies suggest that differences in the microRNAome profiles may underlie the exceptional healing that occurs in oral mucosa. Here, we test whether skin wound-heali
Externí odkaz:
https://doaj.org/article/c642680de0b44f32af7fa34c346cf81e
Autor:
Uzoagu A. Okonkwo, Luisa A. DiPietro
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 7, p 1419 (2017)
Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in sight. Complications of DM2 involve a myriad of comorbidities including the serious complications of poor wound healing, chronic ulceration, and resultant limb a
Externí odkaz:
https://doaj.org/article/ddc8a47842c44935a237ca9dd22b845a