Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Luis Zurkirchen"'
Autor:
Luis Zurkirchen, Sandra Varum, Sonja Giger, Annika Klug, Jessica Häusel, Raphaël Bossart, Martina Zemke, Claudio Cantù, Zeynep Kalender Atak, Nicola Zamboni, Konrad Basler, Lukas Sommer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The transcription factor Yin Yang 1 (YY1) plays an important role in human disease, yet little is known about its role in brain development. This study shows that YY1 controls cerebral cortex development by maintaining proliferation and survival of n
Externí odkaz:
https://doaj.org/article/bc26cd50490644df85c84964bd1b920a
Autor:
Marlen Knobloch, Carolin von Schoultz, Luis Zurkirchen, Simon M.G. Braun, Mojca Vidmar, Sebastian Jessberger
Publikováno v:
Stem Cell Reports, Vol 3, Iss 5, Pp 735-742 (2014)
Proliferation of neural stem/progenitor cells (NSPCs) in the adult brain is tightly controlled to prevent exhaustion and to ensure proper neurogenesis. Several extrinsic stimuli affect NSPC regulation. However, the lack of unique markers led to contr
Externí odkaz:
https://doaj.org/article/0fbaf5156e394a6999fffea744b94488
Autor:
Luis Zurkirchen, Lukas Sommer
Publikováno v:
Current Opinion in Neurobiology. 47:16-23
The neural crest is a transient structure in vertebrate embryos that produces migratory cells with an astonishing developmental potential. While neural crest fate maps have originally been established through interspecies transplantation assays, dye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11948d80496ffeef88f451fcbd1f1ebf
https://doi.org/10.1016/j.conb.2017.07.001
https://doi.org/10.1016/j.conb.2017.07.001
Autor:
Raymond Hoffmans, Tomas Valenta, Claudio Cantù, Kalina Draganova, Magdalena Götz, Luis Zurkirchen, Konrad Basler, Martina Zemke, Michal J. Okoniewski, Marie-Theres Schmid, Lukas Sommer
Publikováno v:
Stem cells (Dayton Ohio)
Stem Cells 33, 170-182 (2015)
Stem Cells 33, 170-182 (2015)
The fate of neural progenitor cells (NPCs) is determined by a complex interplay of intrinsic programs and extrinsic signals, very few of which are known. β-Catenin transduces extracellular Wnt signals, but also maintains adherens junctions integrity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfc0760e7d5d5e574b793ea28fca3b2
Autor:
Jasper Wouters, Raphaël Bossart, Claudio Cantù, Mitchell P. Levesque, Zeynep Kalender Atak, Luis Zurkirchen, Eylul Tuncer, Konrad Basler, Jessica Häusel, Stein Aerts, Sandra Varum, Dominiek Veen, Lukas Sommer, Daniel Zingg, Nessy John, Arianna Baggiolini, Nicola Zamboni, Elisa Marzorati, Marcel Balz, Reinhard Dummer
Publikováno v:
Cell Stem Cell. 24:637-653.e9
Increasing evidence suggests that cancer cells highjack developmental programs for disease initiation and progression. Melanoma arises from melanocytes that originate during development from neural crest stem cells (NCSCs). Here, we identified the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf626285c209a608d7b213f9809cd3a0
https://doi.org/10.1016/j.stem.2019.03.011
https://doi.org/10.1016/j.stem.2019.03.011
Autor:
Raquel A.C. Machado, Marta Roccio, Oezlem Karalay, Werner J. Kovacs, Nicola Zamboni, Carolin von Schoultz, Luis Zurkirchen, Sebastian Jessberger, Matthias P. Lutolf, Simon M. G. Braun, Clay F. Semenkovich, Marlen Knobloch, Marcos J. Araúzo-Bravo, Ueli Suter
Publikováno v:
Nature
Nature, Vol. 493, No 7431 (2013) pp. 226-230
Nature, Vol. 493, No 7431 (2013) pp. 226-230
Mechanisms controlling the proliferative activity of neural stem and progenitor cells (NSPCs) have a pivotal role to ensure life-long neurogenesis in the mammalian brain(1). How metabolic programs are coupled with NSPC activity remains unknown. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efba4b21ae6f99c1c9f12002b213260b
https://doi.org/10.1038/nature11689
https://doi.org/10.1038/nature11689
Autor:
Martina Zemke, Kalina Draganova, Annika Klug, Anne Schöler, Luis Zurkirchen, Max Hans-Peter Gay, Phil Cheng, Haruhiko Koseki, Tomas Valenta, Dirk Schübeler, Konrad Basler, Lukas Sommer
Publikováno v:
BMC Biology
Background Precise spatiotemporal control of gene expression is essential for the establishment of correct cell numbers and identities during brain development. This process involves epigenetic control mechanisms, such as those mediated by the polyco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137057f2ea8bdca9ae884a4ba14fbca2
https://doi.org/10.5167/uzh-115847
https://doi.org/10.5167/uzh-115847
In contrast to the narrow fan of clinical Computed Tomography (CT) scanners, Cone Beam scanners irradiate a much larger proportion of the object, which causes additional X-ray scattering. The most obvious scatter artefact is that the middle area of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2598e21ef6987363d25f438a0869137