Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Luis V. Santana-Quintero"'
Autor:
Douglas Meyer, Jacob Kames, Haim Bar, Anton A. Komar, Aikaterini Alexaki, Juan Ibla, Ryan C. Hunt, Luis V. Santana-Quintero, Anton Golikov, Michael DiCuccio, Chava Kimchi-Sarfaty
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Abstract Background Gene expression is highly variable across tissues of multi-cellular organisms, influencing the codon usage of the tissue-specific transcriptome. Cancer disrupts the gene expression pattern of healthy tissue resulting in altered co
Externí odkaz:
https://doaj.org/article/c7ca96719b204fc496ee0de68b57825b
Autor:
John Athey, Aikaterini Alexaki, Ekaterina Osipova, Alexandre Rostovtsev, Luis V. Santana-Quintero, Upendra Katneni, Vahan Simonyan, Chava Kimchi-Sarfaty
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Due to the degeneracy of the genetic code, most amino acids can be encoded by multiple synonymous codons. Synonymous codons naturally occur with different frequencies in different organisms. The choice of codons may affect protein
Externí odkaz:
https://doaj.org/article/8465e5709807407f9bb996393f34ae42
Autor:
Nobuko Hamasaki-Katagiri, Anton A. Komar, John C. Athey, Aikaterini Alexaki, Luis V. Santana-Quintero, Phuc Vihn Nguyen Lam, Jacob Kames, David D. Holcomb, Haim Bar, Ekaterina Osipova, Vahan Simonyan, Chava Kimchi-Sarfaty
Publikováno v:
Journal of Molecular Biology. 431:2434-2441
Usage of sequential codon-pairs is non-random and unique to each species. Codon-pair bias is related to but clearly distinct from individual codon usage bias. Codon-pair bias is thought to affect translational fidelity and efficiency and is presumed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acb78faad7d118568501f42791fdbb9
https://doi.org/10.1016/j.jmb.2019.04.021
https://doi.org/10.1016/j.jmb.2019.04.021
Autor:
Sean Smith, Emma C. Scott, Lorraine Pelosof, Richard Pazdur, Joseph Wynne, V. Ashutosh Rao, R. Angelo de Claro, Amy S. Rosenberg, Nora Holmes, Alexander J. Ambinder, Wenming Xiao, Kelly J. Norsworthy, Yong Zhang, Catherine Lai, Svetlana Petrovskaya, Luis V. Santana-Quintero, Julia A. Beaver, Gabriel Ghiaur, Michael Colgan, Colleen McGuire, Dickran Kazandjian, Kamil Kural
Publikováno v:
Blood. 138:1285-1285
Background: Ivosidenib (Servier Pharmaceuticals LLC) and enasidenib (Celgene) are inhibitors of mutant IDH1 and IDH2, respectively, approved for the treatment of relapsed/refractory (R/R) AML with an IDH1 or IDH2 mutation (ivosidenib is also approved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec47c98aa7ecd02efe559abbbc7f55f
https://doi.org/10.1182/blood-2021-147099
https://doi.org/10.1182/blood-2021-147099
Autor:
Aikaterini Alexaki, Jacob Kames, Haim Bar, Juan C. Ibla, Luis V. Santana-Quintero, Chava Kimchi-Sarfaty, Nobuko Hamasaki-Katagiri, Upendra K. Katneni, Anton Golikov, David D. Holcomb, John C. Athey
Publikováno v:
Journal of molecular biology. 432(11)
Protein expression in multicellular organisms varies widely across tissues. Codon usage in the transcriptome of each tissue is derived from genomic codon usage and the relative expression level of each gene. We created a comprehensive computational r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65b57fd435ac3f0200ece5798da7a02
https://pubmed.ncbi.nlm.nih.gov/31982380
https://pubmed.ncbi.nlm.nih.gov/31982380
Autor:
Upendra K. Katneni, John C. Athey, Aikaterini Alexaki, Vahan Simonyan, Ekaterina Osipova, Alexandre Rostovtsev, Luis V. Santana-Quintero, Chava Kimchi-Sarfaty
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-10 (2017)
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-10 (2017)
Background Due to the degeneracy of the genetic code, most amino acids can be encoded by multiple synonymous codons. Synonymous codons naturally occur with different frequencies in different organisms. The choice of codons may affect protein expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7dce99621c925ba9a33a5fd39be044
https://pubmed.ncbi.nlm.nih.gov/28865429
https://pubmed.ncbi.nlm.nih.gov/28865429
Autor:
Alfredo G. Hernández-Díaz, Miguel A. Hinojosa, Ana Dolores López-Sánchez, Luis V. Santana-Quintero
Publikováno v:
Computers & Operations Research. 40:1155-1164
Multi-criteria optimization problems are considered where the decision maker is unable to determine the exact weights of importance of the criteria but can provide some imprecise information about these weights. Two solution concepts are studied in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a44348f6930e6f9ff70c2be25ce803e
https://doi.org/10.1016/j.cor.2012.11.019
https://doi.org/10.1016/j.cor.2012.11.019
Autor:
Rafael Caballero, Alfredo G. Hernández-Díaz, Julián Molina, Luis V. Santana-Quintero, Carlos A. Coello Coello
Publikováno v:
Information Sciences. 181:3101-3129
In this paper, we deal with the problem of handling solutions in an external archive with the use of a relaxed form of Pareto dominance called @e-dominance and a variation of it called pa@e-dominance. These two relaxed forms of Pareto dominance have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bf365d49cd71d237763800e78263eb8
https://doi.org/10.1016/j.ins.2011.02.030
https://doi.org/10.1016/j.ins.2011.02.030
Autor:
Julián Molina, Carlos A. Coello Coello, Luis V. Santana-Quintero, Rafael Caballero, Alfredo G. Hernández-Díaz
Publikováno v:
Computers & Operations Research. 37:470-480
The aim of this paper is to show how the hybridization of a multi-objective evolutionary algorithm (MOEA) and a local search method based on the use of rough set theory is a viable alternative to obtain a robust algorithm able to solve difficult cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b39e6a2b8842b1cd83729cb5f1387851
https://doi.org/10.1016/j.cor.2009.02.006
https://doi.org/10.1016/j.cor.2009.02.006
Autor:
Elaine E. Thompson, Raja Mazumder, Hayley Dingerdissen, Konstantin Chumakov, Tsung-Jung Wu, Konstantinos Karagiannis, Anton Golikov, Luis V. Santana-Quintero, Scott Goldweber, Phuc VinhNguyen Lam, Vahan Simonyan, Olesja Muravitskaja, Valery Tkachenko, Quan Wan, William J. Faison, Alexey Pschenichnov, Yang Pan, Jing Wang, Krista Smith, John Torcivia-Rodriguez, Alin Voskanian, Ekaterina Osipova, Carolyn A. Wilson, Naila Gulzar, Alexandre Rostovtsev, Thomas Maudru
Publikováno v:
Database: The Journal of Biological Databases and Curation
The High-performance Integrated Virtual Environment (HIVE) is a distributed storage and compute environment designed primarily to handle next-generation sequencing (NGS) data. This multicomponent cloud infrastructure provides secure web access for au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ceb1ddb9218fbf65a6c67009771b4d
https://pubmed.ncbi.nlm.nih.gov/26989153
https://pubmed.ncbi.nlm.nih.gov/26989153