Zobrazeno 1 - 10
of 375
pro vyhledávání: '"Luis Rivas"'
Autor:
Juan Víctor San Martín-López, Nieves Mesa, David Bernal-Bello, Alejandro Morales-Ortega, Marta Rivilla, Marta Guerrero, Ruth Calderón, Ana I. Farfán, Luis Rivas, Guillermo Soria, Aída Izquierdo, Elena Madroñal, Miguel Duarte, Sara Piedrabuena, María Toledano-Macías, Jorge Marrero, Cristina de Ancos, Begoña Frutos, Rafael Cristóbal, Laura Velázquez, Belén Mora, Paula Cuenca, José Á. Satué, Ibone Ayala-Larrañaga, Lorena Carpintero, Celia Lara, Álvaro R. Llerena, Virginia García, Vanessa García de Viedma, Santiago Prieto, Natalia González-Pereira, Cristina Bravo, Carolina Mariño, Luis Antonio Lechuga, Jorge Tarancón, Sonia Gonzalo, Santiago Moreno, José M. Ruiz-Giardin
Publikováno v:
Viruses, Vol 15, Iss 9, p 1839 (2023)
(1) Background: COVID-19 has evolved during seven epidemic waves in Spain. Our objective was to describe changes in mortality and severity in our hospitalized patients. (2) Method: This study employed a descriptive, retrospective approach for COVID-1
Externí odkaz:
https://doaj.org/article/2cb03b63efd44b35965ae3473f05d95e
Autor:
Lucía Román-Álamo, Mohamad Allaw, Yunuen Avalos-Padilla, Maria Letizia Manca, Maria Manconi, Federica Fulgheri, Jorge Fernández-Lajo, Luis Rivas, José Antonio Vázquez, José Esteban Peris, Xavier Roca-Geronès, Srisupaph Poonlaphdecha, Maria Magdalena Alcover, Roser Fisa, Cristina Riera, Xavier Fernàndez-Busquets
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1163 (2023)
The second-line antileishmanial compound pentamidine is administered intramuscularly or, preferably, by intravenous infusion, with its use limited by severe adverse effects, including diabetes, severe hypoglycemia, myocarditis and renal toxicity. We
Externí odkaz:
https://doaj.org/article/fb91c6dd6dad465e8b155922e5504dc2
Autor:
Sarah Hendrickx, Lieselotte Van Bockstal, Dimitri Bulté, Annelies Mondelaers, Hamide Aslan, Luis Rivas, Louis Maes, Guy Caljon
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-11 (2020)
Abstract Background Since the introduction of miltefosine (MIL) as first-line therapy in the kala-azar elimination programme in the Indian subcontinent, treatment failure rates have been increasing. Since parasite infectivity and virulence may become
Externí odkaz:
https://doaj.org/article/7014af4ac7cf4b78908c0dff4a925fd3
Autor:
Paula Martínez de Iturrate, Victor Sebastián-Pérez, Montserrat Nácher-Vázquez, Catherine S. Tremper, Despina Smirlis, Julio Martín, Ana Martínez, Nuria E. Campillo, Luis Rivas, Carmen Gil
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 199-210 (2020)
Previous reports have validated the glycogen synthase kinase-3 (GSK-3) as a druggable target against the human protozoan parasite Leishmania. This prompted us to search for new leishmanicidal scaffolds as inhibitors of this enzyme from our in-house l
Externí odkaz:
https://doaj.org/article/3b09ef3f651f4ec6a08ecd783dbfddba
Autor:
José M. Ruiz-Giardin, Marta Rivilla, Nieves Mesa, Alejandro Morales, Luis Rivas, Aída Izquierdo, Almudena Escribá, Juan V. San Martín, David Bernal-Bello, Elena Madroñal, Ana I. Farfán, Marta Guerrero, Ruth Calderón, Miguel A. Duarte, Sara I. Piedrabuena, María Toledano-Macías, José Á. Satué, Jorge Marrero, Cristina L. de Ancos, Begoña Frutos, Rafael Cristóbal, Guillermo Soria, Ibone Ayala-Larrañaga, Lorena Carpintero, Miguel de Hita, Celia Lara, Álvaro R. Llerena, Virginia García, Raquel Jiménez, Vanesa García, Elena M. Saiz-Lou, Santiago Prieto, Natalia González-Pereira, Luis Antonio Lechuga, Jorge Tarancón, Sonia Gonzalo
Publikováno v:
Viruses, Vol 14, Iss 10, p 2284 (2022)
Objectives. This study aimed to compare the characteristics of fully and partially vaccinated or unvaccinated coronavirus disease 2019 (COVID-19) patients who were hospitalised in a population of 220,000 habitants. Methods: Retrospective, observation
Externí odkaz:
https://doaj.org/article/dda093b905284b46b8641ff20b23148d
Autor:
Juliane S. Lanza, Virginia M. R. Vallejos, Guilherme S. Ramos, Ana Carolina B. de Oliveira, Cynthia Demicheli, Luis Rivas, Sébastien Pomel, Philippe M. Loiseau, Frédéric Frézard
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1743 (2022)
This work aims to evaluate whether nanoassemblies (NanoSb) made from antimony(V) complexes with octanoyl-N-methylglucamide (SbL8) or decanoyl-N-methylglucamide (SbL10) would effectively target the infection sites in visceral and cutaneous leishmanias
Externí odkaz:
https://doaj.org/article/8e62a4658a024c4a921dceb6b4c0fade
Autor:
Victor Sebastián-Pérez, Paula Martínez de Iturrate, Montserrat Nácher-Vázquez, Luis Nóvoa, Concepción Pérez, Nuria E. Campillo, Carmen Gil, Luis Rivas
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1136 (2022)
More than 1 billion people live in areas endemic for leishmaniasis, which is a relevant threat for public health worldwide. Due to the inadequate treatments, there is an urgent need to develop novel alternative drugs and to validate new targets to fi
Externí odkaz:
https://doaj.org/article/ce30c60ca1094e89aab2b03ea997b1f8
Publikováno v:
Molecules, Vol 25, Iss 24, p 5804 (2020)
Cyanobacteria and microalgae are oxygen-producing photosynthetic unicellular organisms encompassing a great diversity of species, which are able to grow under all types of extreme environments and exposed to a wide variety of predators and microbial
Externí odkaz:
https://doaj.org/article/d3746aaf82804f139438db34198b7be9
Autor:
Alex Echeverría-Vega, Guillermo Chong, Antonio E. Serrano, Mariela Guajardo, Olga Encalada, Victor Parro, Yolanda Blanco, Luis Rivas, Kevin C. Rose, Mercedes Moreno-Paz, José A. Luque, Nathalie A. Cabrol, Cecilia S. Demergasso
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Laguna Negra and Lo Encañado are two oligotrophic Andean lakes forming part of the system fed by meltwater from distinct glacial tongues of the Echaurren glacier in central Chile, which is in a recession period. The recent increase in temperature an
Externí odkaz:
https://doaj.org/article/cdc23534ad8d4b79a1bef4d570c75b3c
Autor:
Edézio Ferreira Cunha-Júnior, Valter Viana Andrade-Neto, Marta Lopes Lima, Thais Alves da Costa-Silva, Andres J Galisteo Junior, Maria A Abengózar, Coral Barbas, Luis Rivas, Elmo Eduardo Almeida-Amaral, Andre Gustavo Tempone, Eduardo Caio Torres-Santos
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 1, p e0005281 (2017)
The leishmanicidal action of tricyclic antidepressants has been studied and evidences have pointed that their action is linked to inhibition of trypanothione reductase, a key enzyme in the redox metabolism of pathogenic trypanosomes. Cyclobenzaprine
Externí odkaz:
https://doaj.org/article/28c6132da48d4a5bbb3836defb2f027e