Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Luis R. Millán-Barea"'
Autor:
Eric H. Bent, Luis R. Millán-Barea, Iris Zhuang, Daniel R. Goulet, Julia Fröse, Michael T. Hemann
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Cytotoxic chemotherapy rarely generates durable anti-tumor immune responses. Here the authors show that tumor microenvironment-derived IL-6 promotes resistance to doxorubicin by suppressing CD8 T cell anti-tumor immune responses in a preclinical mode
Externí odkaz:
https://doaj.org/article/2ab9f39da54444fcbb8306819e59ec2e
Autor:
Daniel R. Goulet, Julia Fröse, Iris Zhuang, Michael T. Hemann, Luis R Millán-Barea, Eric H. Bent
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Cytotoxic chemotherapeutics primarily function through DNA damage-induced tumor cell apoptosis, although the inflammation provoked by these agents can stimulate anti-cancer immune responses. The mechanisms that control these distinct effects and limi