Výsledky vyhledávání - "Luis R. B. Soares"

V7 (CD101) Ligation Inhibits TCR/CD3-Induced IL-2 Production by Blocking Ca2+ Flux and Nuclear Factor of Activated T Cell Nuclear Translocation

Autor: Luis R. B. Soares, Larisa Tsavaler, Alberto Rivas, Edgar G. Engleman

Publikováno v: The Journal of Immunology. 161:209-217

Ligation of the V7 (CD101) molecule on T cells with anti-V7 mAb blocks TCR/CD3-induced proliferation by inhibiting IL-2 transcription. To explore the basis for this observation, we analyzed the effects of V7 ligation on CD3/TCR-induced changes in int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a27332d8a23f7fd6a28206151575c818
https://doi.org/10.4049/jimmunol.161.1.209

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Major histocompatibility complex binding affinity of an antigenic determinant is crucial for the differential secretion of interleukin 4/5 or interferon gamma by T cells

Autor: Eli E. Sercarz, Luis R. B. Soares, J. I. Alexander, Alessandro Sette, Vatsala Bhardwaj, Vipin Kumar

Publikováno v: Proceedings of the National Academy of Sciences. 92:9510-9514

Differential activation of CD4+ T-cell precursors in vivo leads to the development of effectors with unique patterns of lymphokine secretion. To investigate whether the differential pattern of lymphokine secretion is influenced by factors associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d64225a8746789a8f782f6bb090adb3
https://doi.org/10.1073/pnas.92.21.9510

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Vaccination of the Leishmania major susceptible BALB/c mouse. I. The precise selection of peptide determinant influences CD4+ T cell subset expression

Autor: Alexander Miller, Luis R. B. Soares, Eli E. Sercarz

Publikováno v: International Immunology. 6:785-794

BALB/c mice are susceptible to cutaneous leishmaniasis upon infection with Leishmania major while C57BL/6 are not. There is a major promastigote surface protease (PSP or gp63) which is available in both native and recombinant forms, and for which the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c26b2b06b34400a96cc5f692cc76659f
https://doi.org/10.1093/intimm/6.5.785

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Determinant flanking regions and the design of appropriate vaccines

Autor: Alexander Miller, Luis R. B. Soares, Kamal D. Moudgil, Mark Palmer, Vipin Kumar, Iqbal S. Grewal, Hongkui Deng, Eli E. Sercarz

Publikováno v: Annals of the New York Academy of Sciences. 754

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00767e2bdf2105d8661ce1da86a33fb
https://pubmed.ncbi.nlm.nih.gov/7625680

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