Výsledky vyhledávání - "Luis Miguel Alonso"

EphrinA4 plays a critical role in α4 and αL mediated survival of human CLL cells during extravasation

Autor: Francisco José Ortuño, Miguel A. Flores, Gloria Soler, Dolores García, Luis Miguel Alonso-Colmenar, Paula Fortea, Eva M. Trinidad, Agustín G. Zapata

Publikováno v: E-Prints Complutense. Archivo Institucional de la UCM
instname
Oncotarget
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid

A role of endothelial cells in the survival of CLL cells during extravasation is presently unknown. Herein we show that CLL cells but not normal B cells can receive apoptotic signals through physical contact with TNF-α activated endothelium impairin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd793a69cc744b929d819b8acf4b1f4
https://doi.org/10.18632/oncotarget.10311

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Eph/Ephrin-Mediated Interactions in the Thymus

Autor: David Alfaro, Juan J. Muñoz, Luis Miguel Alonso-Colmenar, Teresa Cejalvo, Agustín G. Zapata, Javier García-Ceca

Publikováno v: Neuroimmunomodulation. 18:271-280

In the present study, we review available information on the relevance of Eph and ephrins in numerous processes occurring in the thymus that regulate not only T cell differentiation but also thymic epithelial cell (TEC) development and organization.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a54f6920cde0ef32f2dc2b333e705f67
https://doi.org/10.1159/000329490

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Developing T-cell migration: role of semaphorins and ephrins

Autor: Luis Miguel Alonso-Colmenar, Juan J. Muñoz, David Alfaro, Marco Augusto Stimamiglio, Daniella Arêas Mendes-da-Cruz, Wilson Savino, Eugênia Terra-Granado, Agustín G. Zapata, Javier García-Ceca

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(11)

Cell migration is a crucial event for normal T-cell development, and various ligand/receptor pairs have been implicated. Most of them, including chemokines and extracellular matrix proteins, have attractant properties on thymocytes. We discuss herein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a55762c23152c963ce438e5974f595f
https://pubmed.ncbi.nlm.nih.gov/22815386

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Eph/ephrin signaling in cancer: Intricate, puzzling and ... fascinating!

Autor: Luis Miguel Alonso-Colmenar

The Eph receptor tyrosine kinases family and their membrane bound ligands, the ephrins, represents a complex signaling network of cell communication for cell sorting during tissue patterning in development and in the normal physiology and homeostasis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaabc9f8ba9c93458461d30354759f82
https://europepmc.org/articles/PMC3499308/

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Eph-ephrin bidirectional signaling comes into the context of lymphocyte transendothelial migration

Autor: Eva M. Trinidad, Agustín G. Zapata, Luis Miguel Alonso-Colmenar

Publikováno v: Cell adhesionmigration. 4(3)

A better knowledge of the molecular mechanisms that govern leukocyte trafficking is of major relevance for the clinics. Both normal and pathologic extravasation of lymphocytes are a fine-tuned spatio-temporal event of migratory path-finding, likely r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eae9c690085c14a04115f54a93dcdae
https://pubmed.ncbi.nlm.nih.gov/20400865

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An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression

Autor: Agustín G. Zapata, Jaime Zuloaga, Luis Miguel Alonso-Colmenar, Mónica Ballesteros, Eva M. Trinidad

Publikováno v: Blood. 114(24)

Chronic lymphocytic leukemia (CLL) cell migration into lymphoid tissues is an important aspect of the pathobiology of this disease. Here, we investigated the role of ephrin-A4 (EFNA4) in the transendothelial migration (TEM) capacity of CLL and normal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67f6c899c87cd9fbd712471a35ccf0e
https://pubmed.ncbi.nlm.nih.gov/19828693

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579 Eph/ephrin-B interactions modulate a BAFF-R/TACI dependent survival of chronic lymphocytic leukemia (CLL) cells mediated in vitro by bone marrow stromal cells

Autor: Luis Miguel Alonso-Colmenar, Agustín G. Zapata, Gloria Soler, M.D. García, P. Fortea, Francisco José Ortuño, M.A. Flores, J. García-Cantalejo

Publikováno v: European Journal of Cancer. 50:187

H.S. Leong, A.E. Robertson, K. Stoletov, S.J. Leith, C.A. Chin, A.E. Chien, M.N. Hague, A.L. Ablack, K. Carmine Simmen, V.A. McPherson, C.O. Postenka, E.A. Turley, S.A. Courtneidge, A.F. Chambers, J.D. Lewis. London Regional Cancer Program, Urology,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d14cc2b894ce7f4ea94236457b0cdc39
https://doi.org/10.1016/s0959-8049(14)70705-1

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Development of rat CD45+ 13-day-old fetal liver cells in SCID mouse fetal thymic organ cultures

Autor: Angeles Vicente, Agustín G. Zapata, Alberto Varas, Luis-Miguel Alonso-C

Publikováno v: International immunology. 11(7)

A phenotypic analysis of the lympho-hemopoietic cells which occur in the liver of 13-day-old fetal rats was achieved by flow cytometry in an attempt to further characterize the rat lymphoid progenitor cells. A small fraction of rat 13-day-old fetal l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83b6c6876a2e9924e7b899a86a52887
https://pubmed.ncbi.nlm.nih.gov/10383945

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