Zobrazeno 1 - 10
of 464
pro vyhledávání: '"Luis Menéndez"'
Autor:
Letian Song, Shenghua Gao, Bing Ye, Mianling Yang, Yusen Cheng, Dongwei Kang, Fan Yi, Jin-Peng Sun, Luis Menéndez-Arias, Johan Neyts, Xinyong Liu, Peng Zhan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 1, Pp 87-109 (2024)
The main protease (Mpro) of SARS-CoV-2 is an attractive target in anti-COVID-19 therapy for its high conservation and major role in the virus life cycle. The covalent Mpro inhibitor nirmatrelvir (in combination with ritonavir, a pharmacokinetic enhan
Externí odkaz:
https://doaj.org/article/3f51f2f2ddc7422491491f1bb580fa8a
Autor:
Chuanfeng Liu, Lide Hu, Guanyu Dong, Ying Zhang, Edeildo Ferreira da Silva-Júnior, Xinyong Liu, Luis Menéndez-Arias, Peng Zhan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 12, Pp 4715-4732 (2023)
Influenza is an acute respiratory infection caused by influenza viruses (IFV), According to the World Health Organization (WHO), seasonal IFV epidemics result in approximately 3–5 million cases of severe illness, leading to about half a million dea
Externí odkaz:
https://doaj.org/article/ba338528a0f242a1834806a96f944096
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/ae74040d12824455a43a60a01850249b
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7167 (2024)
The human immunodeficiency virus type 1 (HIV-1) capsid is a protein core formed by multiple copies of the viral capsid (CA) protein. Inside the capsid, HIV-1 harbours all the viral components required for replication, including the genomic RNA and vi
Externí odkaz:
https://doaj.org/article/af502b2a27dd4f1c934f51027fcf6f4a
Autor:
Yang Zhou, Shujing Xu, Nerea López-Carrobles, Dang Ding, Xinyong Liu, Luis Menéndez-Arias, Peng Zhan
Publikováno v:
Acta Materia Medica, Vol 2, Iss 3, Pp 285-298 (2023)
Viral infections represent a major threat to human health and the global economy; however, most of the currently available antiviral drugs are not fully effective in restricting viral replication and selecting for drug-resistant variants. Targeted pr
Externí odkaz:
https://doaj.org/article/f42ea702933c4c6284817f88fde8b8d8
Publikováno v:
Revista Centro Azúcar, Vol 49, Iss 4, Pp 24-34 (2022)
Introducción: El cacao es un cultivo muy importante en Ecuador, debido a las grandes cantidades que se exportan, entre las variedades que se cultivan esta la CCN 51, que es la de mayor rendimiento y debido a que el nivel de procesamiento en término
Externí odkaz:
https://doaj.org/article/7204f6ccfc5143d99a35d9e248bca035
A Rapid, Highly Sensitive and Open-Access SARS-CoV-2 Detection Assay for Laboratory and Home Testing
Autor:
Max J. Kellner, James J. Ross, Jakob Schnabl, Marcus P. S. Dekens, Martin Matl, Robert Heinen, Irina Grishkovskaya, Benedikt Bauer, Johannes Stadlmann, Luis Menéndez-Arias, Andrew D. Straw, Robert Fritsche-Polanz, Marianna Traugott, Tamara Seitz, Alexander Zoufaly, Manuela Födinger, Christoph Wenisch, Johannes Zuber, Vienna COVID-19 Detection Initiative (VCDI), Andrea Pauli, Julius Brennecke
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
RT-qPCR-based diagnostic tests play important roles in combating virus-caused pandemics such as Covid-19. However, their dependence on sophisticated equipment and the associated costs often limits their widespread use. Loop-mediated isothermal amplif
Externí odkaz:
https://doaj.org/article/b9354072a8944c7594458f9ad554e747
Publikováno v:
Viruses, Vol 14, Iss 4, p 841 (2022)
In RNA viruses, a small increase in their mutation rates can be sufficient to exceed their threshold of viability. Lethal mutagenesis is a therapeutic strategy based on the use of mutagens, driving viral populations to extinction. Extinction catastro
Externí odkaz:
https://doaj.org/article/33636d5fa87942abac43093c22964937
Autor:
Cynthia Raissa Tamandjou Tchuem, Laura Brandt, Etienne De la Rey Nel, Mark Fredric Cotton, Philippa Matthews, Francina Kaindjee-Tjituka, Wolfgang Preiser, Monique Ingrid Andersson, Luis Menéndez-Arias
Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
In patients who are HIV infected, hepatitis B virus (HBV) infection is an important co-morbidity. However, antiretroviral options for HIV/HBV co-infected children are limited and, at the time of this study, only included lamivudine. These children ma
Externí odkaz:
https://doaj.org/article/3610c0ef44584e97bb4333a6d8841613
Autor:
Luis Menéndez Antuña
Publikováno v:
Estudios Eclesiásticos, Vol 82, Iss 322, Pp 571-610 (2018)
Las Cartas Pastorales están escritas en un contexto de lucha intracomunitaria. La polémica que se produce en el interior de la comunidad entre la doctrina sana y la «heterodidascalia» es reflejo de las luchas de poder entre dos grupos que pugnan
Externí odkaz:
https://doaj.org/article/eeb0a28f5ed04ac4b5a62867dc0c8627