Young and Especially Senescent Endothelial Microvesicles Produce NADPH: The Fuel for Their Antioxidant Machinery

Autor: Lilian Puebla, Manuel R. Ramírez, Guillermo Bodega, Miriam Morán, Matilde Alique, Luis Magro, Sergio Ciordia, María Carmen Mena, Lourdes Bohorquez, Elvira Arza

Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2018 (2018)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Oxidative Medicine and Cellular Longevity

In a previous study, we demonstrated that endothelial microvesicles (eMVs) have a well-developed enzymatic team involved in reactive oxygen species detoxification. In the present paper, we demonstrate that eMVs can synthesize the reducing power (NAD(

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