Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Luis M. Veggi"'
Autor:
María N Lardizábal, Ana L Nocito, Stella M Daniele, Leonardo A Ornella, Javier F Palatnik, Luis M Veggi
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36323 (2012)
Hepatotoxicity is associated with major changes in liver gene expression induced by xenobiotic exposure. Understanding the underlying mechanisms is critical for its clinical diagnosis and treatment. MicroRNAs are key regulators of gene expression tha
Externí odkaz:
https://doaj.org/article/fb9514676b8e438b920c6de58e2f5ec5
Autor:
Viviana A. Catania, María L. Ruiz, Marcelo G. Luquita, Luis M. Veggi, Aldo D. Mottino, Agostina Arias, Mary Vore, Silvina Stella Maris Villanueva, José M. Pellegrino
Publikováno v:
Drug Metabolism and Disposition. 37:1277-1285
The effect of the cholestatic estrogens ethynylestradiol (EE) and estradiol 17beta-D-glucuronide (E2-17G) on expression and activity of intestinal multidrug resistant-associated protein 2 (Mrp2, Abcc2) was studied in rats. Expression and localization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec45ae536a8f66861773239f7702e5a
https://doi.org/10.1124/dmd.108.025643
https://doi.org/10.1124/dmd.108.025643
Publikováno v:
Toxicology. 211:97-106
The effects of dapsone (DDS) treatment (30 mg/kg body wt, twice a day, for 4 days) on biliary secretory function, with special emphasis on bile salt independent bile flow (BSIF), were investigated in male and in female Wistar rats. Because DDS is met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b20f80cdc342e123791690dd5029a68
https://doi.org/10.1016/j.tox.2005.03.002
https://doi.org/10.1016/j.tox.2005.03.002
Autor:
Aldo D. Mottino, Marcelo G. Roma, Fernando A. Crocenzi, Luis M. Veggi, Enrique J. Sánchez Pozzi, Mary Vore
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 288:G327-G336
Estradiol-17β-d-glucuronide (E2-17G) induces a marked but reversible inhibition of bile flow in the rat together with endocytic retrieval of multidrug resistance-associated protein 2 (Mrp2) from the canalicular membrane to intracellular structures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d079c85a0c75b5ba57ed10a73e1c3c
https://doi.org/10.1152/ajpgi.00227.2004
https://doi.org/10.1152/ajpgi.00227.2004
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 307:306-313
Estradiol-17beta-D-glucuronide (E2-17G) induces an acute but reversible inhibition of bile flow after its intravenous administration to rats, due in part to the endocytic retrieval of the canalicular multidrug resistance-associated transporter protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c836d04053ee3c8e948fbda38aa683
https://doi.org/10.1124/jpet.103.054544
https://doi.org/10.1124/jpet.103.054544
Autor:
Mary Vore, Jingsong Cao, Marcelo G. Roma, Luis M. Veggi, Fernando A. Crocenzi, Aldo D. Mottino
Publikováno v:
Hepatology. 35:1409-1419
Estradiol-17β- D -glucuronide (E 2 17G), an endogenous metabolite of estradiol, induces a potent dose-dependent and reversible inhibition of bile flow in the rat. We analyzed the effect of a single dose of E 2 17G (15 μmol/kg, intravenously) to fem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ce1ce48b5c7932109b2e0a213242828
https://doi.org/10.1053/jhep.2002.33327
https://doi.org/10.1053/jhep.2002.33327
Autor:
Viviana A. Catania, Marcelo G. Luquita, Luis M. Veggi, Aldo D. Mottino, Enrique J. Sánchez Pozzi, José M. Pellegrino, Mary Vore
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1472:82-92
The effect of lactation on UDP-glucuronosyltransferase (UGT) and Glutathione S-transferase (GST) activities was studied in jejunum from mother rats, 14 (LM14) and 21 (LM21) days after delivery. p-Nitrophenol glucuronidation rate was increased in LM14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9f6e36a7e1921d5d93b3980dd847d39
https://doi.org/10.1016/s0304-4165(99)00107-5
https://doi.org/10.1016/s0304-4165(99)00107-5
Autor:
Ana Lía Nocito, Stella Maris Daniele, María Noelia Lardizábal, Ramiro E. Rodriguez, Javier F. Palatnik, Luis M. Veggi
Publikováno v:
Environmental toxicology and pharmacology. 37(1)
MicroRNAs are small RNA molecules that post-transcriptionally regulate gene expression. MicroRNA-122 is the most abundant and specific liver microRNA. Hepatotoxicity involves a significant alteration of liver gene expression. The aim of this work was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f50a5f3a59ac62cfd02484d70f45646
https://pubmed.ncbi.nlm.nih.gov/24388909
https://pubmed.ncbi.nlm.nih.gov/24388909
Autor:
Javier F. Palatnik, Leonardo Ornella, Ana Lía Nocito, Stella Maris Daniele, Luis M. Veggi, María Noelia Lardizábal
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e36323 (2012)
PLoS ONE, Vol 7, Iss 5, p e36323 (2012)
Hepatotoxicity is associated with major changes in liver gene expression induced by xenobiotic exposure. Understanding the underlying mechanisms is critical for its clinical diagnosis and treatment. MicroRNAs are key regulators of gene expression tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13d5ed3841a49f405de96c1368f95e4
https://pubmed.ncbi.nlm.nih.gov/22563491
https://pubmed.ncbi.nlm.nih.gov/22563491
Autor:
Elena J. Ochoa, Viviana A. Catania, Shinichi Ikushiro, Diego R. Taborda, Marcelo G. Luquita, Luis M. Veggi, Aldo D. Mottino, Luciana Pretto, Marcelo G. Roma, Michael D. Coleman, Enrique J. Sánchez Pozzi
Publikováno v:
Life sciences. 83(5-6)
Dapsone (DDS) is currently used in the treatment of leprosy, malaria and in infections with Pneumocystis jirovecii and Toxoplasma gondii in AIDS patients. Adverse effects of DDS involve methemoglobinemia and hemolysis and, to a lower extent, liver da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc82e4e8e4fcb83561d75b361b5489d6
https://pubmed.ncbi.nlm.nih.gov/18602405
https://pubmed.ncbi.nlm.nih.gov/18602405