Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Luis M. Ledezma-Candanoza"'
Autor:
Lidia Riaño-Umbarila, José Alberto Romero-Moreno, Luis M. Ledezma-Candanoza, Timoteo Olamendi-Portugal, Lourival D. Possani, Baltazar Becerril
Publikováno v:
Toxins, Vol 13, Iss 10, p 708 (2021)
A fundamental issue of the characterization of single-chain variable fragments (scFvs), capable of neutralizing scorpion toxins, is their cross-neutralizing ability. This aspect is very important in Mexico because all scorpions dangerous to humans be
Externí odkaz:
https://doaj.org/article/082013439ff84dc78a120083a7f1e414
Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms
Autor:
Lidia Riaño-Umbarila, Ilse V. Gómez-Ramírez, Luis M. Ledezma-Candanoza, Timoteo Olamendi-Portugal, Everardo Remi Rodríguez-Rodríguez, Guillermo Fernández-Taboada, Lourival D. Possani, Baltazar Becerril
Publikováno v:
Toxins, Vol 11, Iss 1, p 32 (2019)
The recombinant antibody fragments generated against the toxic components of scorpion venoms are considered a promising alternative for obtaining new antivenoms for therapy. Using directed evolution and site-directed mutagenesis, it was possible to g
Externí odkaz:
https://doaj.org/article/b1a1459fec9d4171a00ea512e652478f
Autor:
Lourival D. Possani, Luis M. Ledezma-Candanoza, Baltazar Becerril, Lidia Riaño-Umbarila, José Alberto Romero-Moreno, Timoteo Olamendi-Portugal
Publikováno v:
Toxins
Volume 13
Issue 10
Toxins, Vol 13, Iss 708, p 708 (2021)
Volume 13
Issue 10
Toxins, Vol 13, Iss 708, p 708 (2021)
A fundamental issue of the characterization of single-chain variable fragments (scFvs), capable of neutralizing scorpion toxins, is their cross-neutralizing ability. This aspect is very important in Mexico because all scorpions dangerous to humans be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6575800ab614bc9d49de75936f09320e
Autor:
Lidia, Riaño-Umbarila, José Alberto, Romero-Moreno, Luis M, Ledezma-Candanoza, Timoteo, Olamendi-Portugal, Lourival D, Possani, Baltazar, Becerril
Publikováno v:
Toxins
A fundamental issue of the characterization of single-chain variable fragments (scFvs), capable of neutralizing scorpion toxins, is their cross-neutralizing ability. This aspect is very important in Mexico because all scorpions dangerous to humans be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93782800702920f4ec43f20284e8f711
https://pubmed.ncbi.nlm.nih.gov/34679001
https://pubmed.ncbi.nlm.nih.gov/34679001
Autor:
Luis M. Ledezma-Candanoza, Clarita Olvera, Agustín López-Munguía, José Luis Fernández-Vázquez
Publikováno v:
Microbiology. 153:3994-4002
dsrP, a gene that encodes a cell-associated dextransucrase produced by Leuconostoc mesenteroides IBT-PQ, was isolated, sequenced and expressed in Escherichia coli. From sequence analysis, seven repeat units in the N-terminal region were found, as wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a307daa07907621d4312972dc2ed451a
https://doi.org/10.1099/mic.0.2007/008854-0
https://doi.org/10.1099/mic.0.2007/008854-0
Autor:
Guillermo Fernández-Taboada, Lourival D. Possani, Luis M. Ledezma-Candanoza, Lidia Riaño-Umbarila, Baltazar Becerril, Hugo Serrano-Posada, Ilse V. Gómez-Ramírez, Timoteo Olamendi-Portugal, Enrique Rudiño-Piñera, S.P. Rojas-Trejo
Publikováno v:
The Journal of biological chemistry. 291(4)
The current trend of using recombinant antibody fragments in research to develop novel antidotes against scorpion stings has achieved excellent results. The polyclonal character of commercial antivenoms, obtained through the immunization of animals a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa06bedede3d545ad3eff7d8b593a81
https://pubmed.ncbi.nlm.nih.gov/26589800
https://pubmed.ncbi.nlm.nih.gov/26589800
Autor:
Lourival D. Possani, Lidia Riaño-Umbarila, Luis M. Ledezma-Candanoza, Everardo Remi Rodríguez-Rodríguez, Luis Gabriel Contreras-Ferrat, Timoteo Olamendi-Portugal, Baltazar Becerril
Publikováno v:
Journal of molecular biology. 423(3)
Excellent results regarding improved therapeutic properties have been often obtained through the conversion of a single‐chain variable fragment (scFv) into a noncovalent dimeric antibody (diabody) via peptide linker shortening. We utilized this app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55637e032c1a397a4407a7131c92eae
https://pubmed.ncbi.nlm.nih.gov/22835504
https://pubmed.ncbi.nlm.nih.gov/22835504