Zobrazeno 1 - 10
of 532
pro vyhledávání: '"Luis M. Botana"'
Autor:
Alejandro Cao, Natalia Vilariño, Lisandra de Castro-Alves, Yolanda Piñeiro, José Rivas, Ana M. Botana, Cristina Carrera, María J. Sainz, Luis M. Botana
Publikováno v:
Toxins, Vol 16, Iss 6, p 269 (2024)
The rise in cyanobacterial blooms due to eutrophication and climate change has increased cyanotoxin presence in water. Most current water treatment plants do not effectively remove these toxins, posing a potential risk to public health. This study in
Externí odkaz:
https://doaj.org/article/1086cfafc45246f1b49ea10a103539c6
Autor:
Rebeca Alvariño, Cristina Gil-Mouce, Manuel A. Botana, Sandra Gegunde, Jesús González-Jartín, Mercedes R. Vieytes, Amparo Alfonso, Luis M. Botana
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Cyclophilins are a family of chaperones involved in inflammation and cell death. Cyclophilin B is released by inflammatory cells and acts through the receptor CD147, affecting matrix metalloproteases release, whilst cyclophilin D participate
Externí odkaz:
https://doaj.org/article/9e7d78d6ab8b46409c514cbe04740722
Autor:
Sandra Raposo-García, Ana M. Botana, Verónica Rey, Celia Costas, Luis Rodríguez-Santos, M. Carmen Louzao, Carmen Vale, Luis M. Botana
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25338- (2024)
Paralytic shellfish poisoning is a foodborne illness that typically derive from the consumption of shellfish contaminated with saxitoxin-group of toxins produced by dinoflagellates of the genus Gymnodinium, Alexandrium and Pyrodinium. N-sulfocarbamoy
Externí odkaz:
https://doaj.org/article/48da08e2e9b54b4ebe56b1fd524b2d58
Publikováno v:
Food Chemistry Advances, Vol 2, Iss , Pp 100289- (2023)
The chemical methodology to quantify paralytic shellfish toxins (PSTs) is ultrahigh-performance liquid chromatography with fluorescence detection and precolumn oxidation. It has been established as the European Union (EU) reference method replacing t
Externí odkaz:
https://doaj.org/article/34d2446696f14d41923c1dd4227c7e60
Autor:
Sandra Gegunde, Amparo Alfonso, Rebeca Alvariño, Nadia Pérez-Fuentes, Jeremías Bayón-Lorenzo, Eva Alonso, Raymundo Ocaranza-Sánchez, Rosa Alba Abellás-Sequeiros, Melisa Santás-Álvarez, Mercedes R. Vieytes, Carlos Juanatey-González, Luis M. Botana
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Cyclophilins are chaperone proteins that play important roles in signal transduction. Among them, cyclophilins A, B, C, and D were widely associated with inflammation and cardiovascular diseases. Cyclophilins A and C have been proposed as coronary ar
Externí odkaz:
https://doaj.org/article/2b8f360f081d4f7b97144d5083c53e4e
Autor:
Sandra Raposo-Garcia, Alejandro Cao, Celia Costas, M. Carmen Louzao, Natalia Vilariño, Carmen Vale, Luis M. Botana
Publikováno v:
Marine Drugs, Vol 21, Iss 11, p 590 (2023)
The growing concern about ciguatera fish poisoning (CF) due to the expansion of the microorganisms producing ciguatoxins (CTXs) increased the need to develop a reliable and fast method for ciguatoxin detection to guarantee food safety. Cytotoxicity a
Externí odkaz:
https://doaj.org/article/943d576f853449bb854937cd63139b79
Autor:
Rebeca Alvariño, Amparo Alfonso, Nadia Pérez-Fuentes, Jesús M. González-Jartín, Sandra Gegunde, Mercedes R. Vieytes, Luis M. Botana
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Extracellular cyclophilins (eCyps) A and B are chemotactic mediators in several illnesses in which inflammation plays an important role such as diabetes and cardiovascular diseases. Recently, eCypC has been reported as a potential biomarker for coron
Externí odkaz:
https://doaj.org/article/b48892d2780048a58e87753cfe3c0968
Autor:
Celso Alves, Joana Silva, Susete Pintéus, Romina A. Guedes, Rita C. Guedes, Rebeca Alvariño, Rafaela Freitas, Márcia I. Goettert, Helena Gaspar, Amparo Alfonso, Maria C. Alpoím, Luis M. Botana, Rui Pedrosa
Publikováno v:
Marine Drugs, Vol 20, Iss 10, p 652 (2022)
Seaweeds are a great source of compounds with cytotoxic properties with the potential to be used as anticancer agents. This study evaluated the cytotoxic and proteasome inhibitory activities of 12R-hydroxy-bromosphaerol, 12S-hydroxy-bromosphaerol, an
Externí odkaz:
https://doaj.org/article/bc54545d70a44a7d8be2f79dfe2a9a41
Autor:
Juan A. Rubiolo, Emilio Lence, Concepción González-Bello, María Roel, José Gil-Longo, Manuel Campos-Toimil, Eva Ternon, Olivier P. Thomas, Antonio González-Cantalapiedra, Henar López-Alonso, Mercedes R. Vieytes, Luis M. Botana
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Crambescins are guanidine alkaloids from the sponge Crambe crambe. Crambescin C1 (CC) induces metallothionein genes and nitric oxide (NO) is one of the triggers. We studied and compared the in vitro, in vivo, and in silico effects of some crambescine
Externí odkaz:
https://doaj.org/article/1eef203b891b4fab85fd7cc696d7ece3
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cyclophilins (Cyps) are a group of peptidyl-prolyl cis/trans isomerases that play crucial roles in regulatory mechanisms of cellular physiology and pathology in several inflammatory conditions. Their receptor, CD147, also participates in the developm
Externí odkaz:
https://doaj.org/article/43177e8aadb34adc8303631b9b36a567