Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Luis M. Agosto"'
Autor:
S Lal, Andrew J. Henderson, Zhaorong Li, JI Fuxman Bass, Maninjay K. Atianand, S Yuan, Luis M. Agosto, Xueming Liu, Ka Gan, Clarissa Stephanie Santoso, Jared A. Sewell, S Carrasco Pro
Publikováno v:
Nucleic Acids Research
Proper cytokine gene expression is essential in development, homeostasis and immune responses. Studies on the transcriptional control of cytokine genes have mostly focused on highly researched transcription factors (TFs) and cytokines, resulting in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e441eea69441cf2f67ee17e07ad012
http://europepmc.org/articles/PMC7708076
http://europepmc.org/articles/PMC7708076
Publikováno v:
J Infect Dis
Background Mycobacterium tuberculosis (Mtb) and human immunodeficiency virus (HIV) coinfection increases mortality, accelerates progression to acquired immune deficiency syndrome, and exacerbates tuberculosis disease. However, the impact of pre-exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd05bd2267779abb79324f9cd1a521b
https://doi.org/10.1093/infdis/jiaa257
https://doi.org/10.1093/infdis/jiaa257
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003982 (2014)
HIV-1 cell-to-cell transmission allows for 2-3 orders of magnitude more efficient viral spread than cell-free dissemination. The high local multiplicity of infection (MOI) observed at cell-cell contact sites may lower the efficacy of antiretroviral t
Externí odkaz:
https://doaj.org/article/77e62d58c4a947549b61ec6e58e2b001
Autor:
Luis M. Agosto, Juan I. Fuxman Bass, Kimberly A. Eberenz, Andrew J. Henderson, Kyle D. Pedro, Xianbao He, Jared A. Sewell
Publikováno v:
Proc Natl Acad Sci U S A
The molecular networks involved in the regulation of HIV replication, transcription, and latency remain incompletely defined. To expand our understanding of these networks, we performed an unbiased high-throughput yeast one-hybrid screen, which ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad3ac668ed52e0d1f59c0ec3a6e9646
https://europepmc.org/articles/PMC7980386/
https://europepmc.org/articles/PMC7980386/
Autor:
Peng Zhong, Luis M Agosto, Anna Ilinskaya, Batsukh Dorjbal, Rosaline Truong, David Derse, Pradeep D Uchil, Gisela Heidecker, Walther Mothes
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53138 (2013)
Virus transmission can occur either by a cell-free mode through the extracellular space or by cell-to-cell transmission involving direct cell-to-cell contact. The factors that determine whether a virus spreads by either pathway are poorly understood.
Externí odkaz:
https://doaj.org/article/72539e0c467a4824b3793e5ecd360150
Autor:
Matthew J Pace, Erin H Graf, Luis M Agosto, Angela M Mexas, Frances Male, Troy Brady, Frederic D Bushman, Una O'Doherty
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002818 (2012)
Despite the effectiveness of highly active antiretroviral therapy (HAART) in treating individuals infected with HIV, HAART is not a cure. A latent reservoir, composed mainly of resting CD4+T cells, drives viral rebound once therapy is stopped. Unders
Externí odkaz:
https://doaj.org/article/dbccde35766d4ad09774f366e3f2ac9f
Autor:
Jean-Robert Larrieux, Manish Sagar, Andrew J. Henderson, Luis M. Agosto, Suryaram Gummuluru, Alex Olson, Hisashi Akiyama, Victor Pena-Cruz, Yvetane Moreau
Publikováno v:
Journal of Clinical Investigation. 128:3439-3444
HIV-1 acquisition occurs most commonly after sexual contact. To establish infection, HIV-1 must infect cells that support high-level replication, namely CD4+ T cells, which are absent from the outermost genital epithelium. Dendritic cells (DCs), pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::015060ec733da6b8c42ff69d1e203f00
https://doi.org/10.1172/jci98943
https://doi.org/10.1172/jci98943
Publikováno v:
Virus Res
HIV-1 spreads through both the release of cell-free particles and by cell-to-cell transmission. Mounting evidence indicates that cell-to-cell transmission is more efficient than cell-free transmission of particles and likely influences the pathogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27594309a1b0f72395aafd6d0fd96108
https://europepmc.org/articles/PMC6467521/
https://europepmc.org/articles/PMC6467521/
Autor:
Andrew J. Henderson, Luis M. Agosto
Latent infection of CD4(+) T cells is the main barrier to eradicating HIV-1 infection from infected patients. The cellular and molecular mechanisms involved in the establishment and maintenance of latent infection are directly linked to the transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea264b33e3a0e265b5e1c64b14274907
https://europepmc.org/articles/PMC6152855/
https://europepmc.org/articles/PMC6152855/
Publikováno v:
Cell reports. 24(8)
Summary HIV-1 is transmitted between T cells through the release of cell-free particles and through cell-cell contact. Cell-to-cell transmission is more efficient than cell-free virus transmission, mediates resistance to immune responses, and facilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b153bfa01778746dc5ae70a0e7c5c4ea
https://pubmed.ncbi.nlm.nih.gov/30134170
https://pubmed.ncbi.nlm.nih.gov/30134170