Výsledky vyhledávání - "Luis I. Sánchez-Abarca"

Akademický článek

Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population

Autor: Belén Blanco, José A. Pérez-Simón, Luis I. Sánchez-Abarca, Teresa Caballero-Velazquez, Silvia Gutierrez-Cossío, Pilar Hernández-Campo, María Díez-Campelo, Carmen Herrero-Sanchez, Concepción Rodriguez-Serrano, Carlos Santamaría, Fermín M. Sánchez-Guijo, Consuelo del Cañizo, Jesús F. San Miguel

Publikováno v: Haematologica, Vol 94, Iss 7 (2009)

Background In vitro depletion of alloreactive T cells using the proteasome inhibitor bortezomib is a promising approach to prevent graft-versus-host disease after allogeneic stem cell transplantation. We have previously described the ability of borte

Externí odkaz: https://doaj.org/article/4f97eaf78a574f4b88980ce89c2d40b4

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Akademický článek

The effect of mesenchymal stem cells on the viability, proliferation and differentiation of B-lymphocytes

Autor: Soraya Tabera, José A. Pérez-Simón, María Díez-Campelo, Luis I. Sánchez-Abarca, Belén Blanco, Antonio López, Ana Benito, Enrique Ocio, Fermín M. Sánchez-Guijo, Consuelo Cañizo, Jesús F. San Miguel

Publikováno v: Haematologica, Vol 93, Iss 9 (2008)

Background Mesenchymal stem cells are multilineage non-hematopoietic progenitor cells that play a key role in supporting the lymphohematopoietic system. Their distribution in bone marrow and secondary lymphoid organs allows an intimate interaction wi

Externí odkaz: https://doaj.org/article/3affdecd37e046fea057ca6bb9f25e5d

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Supplementary Table 1. Toxicity. from Immunomodulatory Effect of Vitamin D after Allogeneic Stem Cell Transplantation: Results of a Prospective Multicenter Clinical Trial

Autor: José A. Pérez-Simón, Francisco J. Márquez-Malaver, Lucía López-Corral, Luis I. Sánchez-Abarca, Antonio Carrillo-Vico, Marian Cuesta, Christelle Ferra i Coll, Oriana López-Godino, David Valcarcel, Raquel Saldaña, Rocío Parody, Fermín Sánchez-Guijo, Isabel Montero, Teresa Caballero-Velázquez

Toxicities according to the criteria by National Cancer Institute are described in this table.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a545f45166de0a76fb8ab7c7d0088ffc
https://doi.org/10.1158/1078-0432.22466594

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Data from Immunomodulatory Effect of Vitamin D after Allogeneic Stem Cell Transplantation: Results of a Prospective Multicenter Clinical Trial

Purpose: We describe the results of a prospective multicenter phase I/II trial evaluating the impact of the use of vitamin D (VitD) from day −5 to +100 on the outcome of patients undergoing allogeneic transplantation (EudraCT: 2010-023279-25; Clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebcc50ffddbb4a79c6419f218fc2d1fb
https://doi.org/10.1158/1078-0432.c.6526364

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Supplementary Table 4. Serum levels of vitamin D. from Immunomodulatory Effect of Vitamin D after Allogeneic Stem Cell Transplantation: Results of a Prospective Multicenter Clinical Trial

Serum levels of vitamin D. Serum levels of vitamin D. The plasma levels of 25-hydroxi-VitD are summarized in this table

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fc4de6dbb6ee9890057161a4e1c163
https://doi.org/10.1158/1078-0432.22466585.v1

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Supplementary Table 3. Serum levels of cytokines by flow cytometry. from Immunomodulatory Effect of Vitamin D after Allogeneic Stem Cell Transplantation: Results of a Prospective Multicenter Clinical Trial

Serum levels of cytokines by flow cytometry. Serum levels of Th1/Th2 cytokines are summarized in this table.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e3727b16ea55395706989d5060f13f
https://doi.org/10.1158/1078-0432.22466588

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Supplementary Figure A1 online only. from Immunomodulatory Effect of Vitamin D after Allogeneic Stem Cell Transplantation: Results of a Prospective Multicenter Clinical Trial

Cumulative incidence of relapse (A) or NRM (B): No significant differences between the different cohorts of patients were observed in terms of cumulative incidence of relapse or NRM (p=0.1 and p= 0.8).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ea4315ddca1e6fb9f4b7844d3c1adb
https://doi.org/10.1158/1078-0432.22466597

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Supplementary Table 2, online only. Immune recovery after allo-stem cell transplantation from Immunomodulatory Effect of Vitamin D after Allogeneic Stem Cell Transplantation: Results of a Prospective Multicenter Clinical Trial

Immune recovery after allo-stem cell transplantation. Mean and standard error of the mean (SEM)of different subpobpopulation of immune system are summarized in this table.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5454a0d0d64648b943bfe2348ce0b5a8
https://doi.org/10.1158/1078-0432.22466591

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Akademický článek

Selection of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients Through the Identification of T-Cells Capable to Establish Stable Interactions With the Leukemic Cells: 'Doublet Technology'

Autor: Estefanía García-Guerrero, Luís I. Sánchez-Abarca, Esther Domingo, Teresa L. Ramos, Jose A. Bejarano-García, Jose A. Gonzalez-Campos, Teresa Caballero-Velázquez, Jose A. Pérez-Simón

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

The relevance of the immune system in cancer has long been studied. Autologous adoptive T cell therapies, based on the use of tumor infiltrating lymphocytes (TILs), have made great progress in recent years for the treatment of solid tumors, especiall

Externí odkaz: https://doaj.org/article/b30349e6feb14b70af54c005f9f65a5b

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