Výsledky vyhledávání - "Luis Gomez-Castillo"

COMBINES-CID: An Efficient Method for De Novo Engineering of Highly Specific Chemically Induced Protein Dimerization Systems

Autor: Huayi Jiang, Frank DiMaio, Shoukai Kang, Molly Jahn, Kristian Davidsen, Liangcai Gu, Mahmoud Moussa, Luis Gomez-Castillo, Zengpeng Li, Yu Liang, Xiaonan Fu

Publikováno v: Journal of the American Chemical Society. 141:10948-10952

Chemically induced dimerization (CID) systems, in which two proteins dimerize only in the presence of a small molecule ligand, offer versatile tools for small molecule sensing and actuation. However, only a handful of CID systems exist and creating o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ffd14e4e82665367100bd81a8c4521d
https://doi.org/10.1021/jacs.9b03522

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Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library

Autor: Huayi Jiang, Liangcai Gu, Shoukai Kang, Luis Gomez-Castillo, Kurumi Watanabe

Publikováno v: Journal of Visualized Experiments.

Protein dimerization events that occur only in the presence of a small-molecule ligand enable the development of small-molecule biosensors for the dissection and manipulation of biological pathways. Currently, only a limited number of chemically indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1445cfef6559ecc0db7e6e535c6b06c5
https://doi.org/10.3791/60738-v

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