Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Luis G. Villa-Diaz"'
Publikováno v:
Bioengineering, Vol 10, Iss 9, p 999 (2023)
Human embryonic stem cells and induced pluripotent stem cells (hPSC) have an unprecedented opportunity to revolutionize the fields of developmental biology as well as tissue engineering and regenerative medicine. However, their applications have been
Externí odkaz:
https://doaj.org/article/dfe205c547574a9d984d8110b470580e
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 7, Pp 681-693 (2019)
Abstract Induced pluripotent stem cells (iPSCs) are cells genetically reprogrammed from somatic cells, which can be differentiated into neurological lineages with the aim to replace or assist damaged neurons in the treatment of spinal cord injuries (
Externí odkaz:
https://doaj.org/article/df6785470e65464d81c59c9e49f5438b
Autor:
Tyler M. Parsons, Daniel Czarnowski, Gerard J. Madlambayan, Luis G. Villa-Diaz, Gabriele D Bigoni-Ordóñez
Publikováno v:
Current Stem Cell Research & Therapy. 14:428-436
Cancer is a highly prevalent and potentially terminal disease that affects millions of individuals worldwide. Here, we review the literature exploring the intricacies of stem cells bearing tumorigenic characteristics and collect evidence demonstratin
Autor:
Paul H. Krebsbach, Cheri X. Deng, Byoung Choul Kim, Tuğba Topal, Shuichi Takayama, Luis G. Villa-Diaz
Publikováno v:
Integrative biology : quantitative biosciences from nano to macro, vol 11, iss 2
Human embryonic stem cells subjected to a one-time uniaxial stretch for as short as 30-min on a flexible substrate coated with Matrigel experienced rapid and irreversible nuclear-to-cytoplasmic translocation of NANOG and OCT4, but not Sox2. Transloca
Autor:
Tyler M. Parsons, Katie L. Buelow, Alaa Hanna, Marisa A. Brake, Crystal Poma, Sarah E. Hosch, Randal J. Westrick, Luis G. Villa-Diaz, George D. Wilson, Gerard J. Madlambayan
Publikováno v:
Br J Cancer
BACKGROUND: Bone-marrow-derived haematopoietic stem and progenitor cells (HSPCs) are a prominent part of the highly complex tumour microenvironment (TME) where they localise within tumours and maintain haematopoietic potency. Understanding the role H
Autor:
Luis G. Villa-Diaz, Paul H. Krebsbach
Publikováno v:
Stem cells and development, vol 26, iss 15
Stem cells have the capacity for self-renewal and differentiation into specialized cells that form and repopulated all tissues and organs, from conception to adult life. Depending on their capacity for differentiation, stem cells are classified as to
Publikováno v:
Orthodonticscraniofacial research. 22
Objectives Skeletal stem cells (SSCs) are characterized by expression of cell surface biomarkers and their ability to differentiate into bone, cartilage and fat. However, the current biomarkers used to identify these cell populations are not cell-typ
Publikováno v:
Stem Cells. 34:588-600
Although a specific group of transcription factors such as OCT4, SOX2, and NANOG are known to play essential roles in pluripotent stem cell (PSC) self-renewal, pluripotency, and reprogramming, other factors and the key signaling pathways regulating t
Publikováno v:
Biomaterials. 35:9581-9590
Well-defined culture conditions are essential for realizing the full potential of human embryonic stem cells (hESCs) in regenerative medicine where large numbers of cells are required. Synthetic polymers such as poly[2-(methacryloyloxy) ethyl dimethy
Autor:
Julie Di Bernardo, K. Sue O'Shea, Shaun M. Kunisaki, Luis G. Villa-Diaz, Omar S. Mabrouk, Guihua Jiang, Paul H. Krebsbach, Michael M. Maiden
Publikováno v:
Stem Cells and Development. 23:2613-2625
The establishment of a reliable prenatal source of autologous, transgene-free progenitor cells has enormous potential in the development of regenerative-medicine-based therapies for infants born with devastating birth defects. Here, we show that a la