Role of Moonlighting Proteins in Disease: Analyzing the Contribution of Canonical and Moonlighting Functions in Disease Progression

Autor: Mario Huerta, Luis Franco-Serrano, Isaac Amela, Josep Antoni Perez-Pons, Jaume Piñol, Angel Mozo-Villarías, Enrique Querol, Juan Cedano

Publikováno v: Cells, Vol 12, Iss 2, p 235 (2023)

The term moonlighting proteins refers to those proteins that present alternative functions performed by a single polypeptide chain acquired throughout evolution (called canonical and moonlighting, respectively). Over 78% of moonlighting proteins are

Externí odkaz: https://doaj.org/article/7f1642b63fd848cfbb020841551cac04

Pathogen Moonlighting Proteins : From Ancestral Key Metabolic Enzymes to Virulence Factors

Autor: Enrique Querol, Josep A. Pérez-Pons, Sergio Hernández, Luis Franco-Serrano, Angel Mozo-Villarias, Juan Cedano, Jaume Piñol, Araceli Nájar-García, David Sánchez-Redondo, Isaac Amela

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Microorganisms
Microorganisms, Vol 9, Iss 1300, p 1300 (2021)

Moonlighting and multitasking proteins refer to proteins with two or more functions performed by a single polypeptide chain. An amazing example of the Gain of Function (GoF) phenomenon of these proteins is that 25% of the moonlighting functions of ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deab9ccd2ea71a9b2e323f3d781b2603
https://ddd.uab.cat/record/256445

Multifunctional Proteins : Involvement in Human Diseases and Targets of Current Drugs

Autor: JosepAntoni Perez-Pons, Angel Mozo-Villarias, Jaume Piñol, Sergio Hernández, Luis Franco-Serrano, Enrique Querol, Mario Huerta, Isaac Amela, Juan Cedano

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Repositorio Abierto de la UdL
Universitad de Lleida
The Protein Journal

Multifunctionality or multitasking is the capability of some proteins to execute two or more biochemical functions. The objective of this work is to explore the relationship between multifunctional proteins, human diseases and drug targeting. The ana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef929d79124ec3cb276432f4eb4b10fd
https://ddd.uab.cat/record/227993

Role of Moonlighting Proteins in Disease: Analyzing the Contribution of Canonical and Moonlighting Functions in Disease Progression.

Autor: Huerta, Mario¹ (AUTHOR), Franco-Serrano, Luis¹ (AUTHOR), Amela, Isaac¹ (AUTHOR), Perez-Pons, Josep Antoni¹ (AUTHOR), Piñol, Jaume¹ (AUTHOR), Mozo-Villarías, Angel¹ (AUTHOR), Querol, Enrique¹ (AUTHOR), Cedano, Juan¹ (AUTHOR) juanantonio.cedano@uab.cat

Publikováno v: Cells (2073-4409). Jan2023, Vol. 12 Issue 2, p235. 21p.

New Disease Progression Research from Universitat Autonoma de Barcelona Outlined (Role of Moonlighting Proteins in Disease: Analyzing the Contribution of Canonical and Moonlighting Functions in Disease Progression).

Publikováno v: Health & Medicine Week; 2/10/2023, p3023-3023, 1p