Gestational Hypothyroxinemia Affects Its Offspring With a Reduced Suppressive Capacity Impairing the Outcome of the Experimental Autoimmune Encephalomyelitis

Autor: Henny Haensgen, Eduardo Albornoz, María C. Opazo, Katherinne Bugueño, Evelyn Liliana Jara Fernández, Rebecca Binzberger, Tomás Rivero-Castillo, Luis F. Venegas Salas, Felipe Simon, Claudio Cabello-Verrugio, Alvaro A. Elorza, Alexis M. Kalergis, Susan M. Bueno, Claudia A. Riedel

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Hypothyroxinemia (Hpx) is a thyroid hormone deficiency (THD) condition highly frequent during pregnancy, which although asymptomatic for the mother, it can impair the cognitive function of the offspring. Previous studies have shown that maternal hypo

Externí odkaz: https://doaj.org/article/e5744f5a2b6e4fef84d314b937121829

Prevalence of filaggrin loss-of-function variants in Chilean population with and without atopic dermatitis

Autor: Macarena Tejos-Bravo, Luis F Venegas-Salas, G. V. Cardenas, Paola Casanello, María Cecilia Poli, Gabriela M. Repetto, Carolina Cabalín, Caroll Hernández, Carolina Iturriaga, Juan P Fraga, Boris Rebolledo, Arturo Borzutzky, Marcela Urzúa, Jose A. Castro-Rodriguez, Guillermo Perez-Mateluna

Publikováno v: International journal of dermatologyReferences. 61(3)

Filaggrin (FLG) loss-of-function variants are major genetic risk factors for atopic dermatitis (AD), but these have not been studied in Latin American populations with and without AD.FLG variants R501X and 2282del4 were genotyped in 275 Chilean adult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32389db132640d11cc09401074aaff59
https://pubmed.ncbi.nlm.nih.gov/34480753

Role of dendritic cells in peanut allergy

Autor: Arturo Borzutzky, Raquel Aguilera-Insunza, Luis F. Venegas, Mirentxu Iruretagoyena, Leticia Rojas

Publikováno v: Expert Review of Clinical Immunology. 14:367-378

The prevalence of peanut allergy (PA) has increased, affecting approximately 1.1% of children in Western countries. PA causes life-threatening anaphylaxis and frequently persists for life. There are no standardized curative therapies for PA, and avoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327b06c523e5b7637087db61217f25b2
https://doi.org/10.1080/1744666x.2018.1467757

Imprinting of maternal thyroid hormones in the offspring

Autor: Luis F. Venegas, Alexis M. Kalergis, Henny Haensgen, Hélène Boudin, Carlos E. Fardella, Maria Cecilia Opazo, Felipe Simon, Alvaro A. Elorza, Karen Bohmwald, Susan M. Bueno, Claudia A. Riedel

Publikováno v: International Reviews Of Immunology
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
International Reviews of Immunology
International Reviews of Immunology, 2017, 36 (4), pp.240-255. ⟨10.1080/08830185.2016.1277216⟩

International audience; Thyroid hormones (THs) during pregnancy contribute significantly to cellular differentiation and development in several tissues of the offspring, principally the central nervous system (CNS). TH deficiencies, such as hypothyro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f47b34238142634b0cc63ac434242bc
https://pubmed.ncbi.nlm.nih.gov/28272924

The blood brain barrier of the offspring gestated in hypothyroxinemia has higher permeability to macromolecules and to the transmigration of immune cells to the central nervous system

Autor: Susan M. Bueno, M.C. Opazo, P. Toledo, F. Gómez, Claudia A. Riedel, Alexis M. Kalergis, Luis F. Venegas, N. Blanco

Publikováno v: Placenta. 51:124

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a57eb4a1efe7cce9c784255f63ca006c
https://doi.org/10.1016/j.placenta.2017.01.088