Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Luis F. Pacheco Otalora"'
Autor:
Grace V. E. Pardo, Eros Emanuel Alfaro Saca, Christell Tatiana Becerra Flores, Walter Fares Delgado Casós, Luis F. Pacheco‐Otalora
Publikováno v:
Developmental Psychobiology. 65
Animal models are crucial to understanding the mechanisms underlying the deleterious consequences of early-life stress. Here, we aimed to examine the effect of the limited bedding nesting (LBN) paradigm on early life development milestones and anxiet
Autor:
Luis F. Pacheco Otalora, Carla A. Scorza, Emilio R. Garrido-Sanabria, Bruno Henrique Silva Araujo, Mauro Schneider Oliveira, Esper A. Cavalheiro, Laila Brito Torres, L.A. Leite
Publikováno v:
Neuroscience. 177:252-268
Proechimys (Rodentia: Echimyidae) is a neotropical rodent of the Amazon region that has been successfully colonized in the laboratory and used for experimental medicine. Preliminary studies indicated that Proechimys (casiragua) rodents express an aty
Autor:
Boris Ermolinsky, Luis F. Pacheco Otalora, Ileana Garcia, Masoud M. Zarei, Frank Skinner, Emilio R. Garrido-Sanabria, Massoud F. Arshadmansab
Publikováno v:
Neuroscience Research. 69:73-80
Functional properties of large conductance Ca(2+) activated potassium (BK) channels are determined by complex alternative splicing of the Kcnma1 gene encoding the alpha pore-forming subunit. Inclusion of the STREX exon in a C-terminal splice site is
Autor:
Hans-Günther Knaus, Luis F. Pacheco Otalora, Ileana Garcia, Frank Skinner, Carlos Fernando Mello, Boris Ermolinsky, Emilio R. Garrido-Sanabria, Massoud F. Arshadmansab, Mauro Schneider Oliveira
Publikováno v:
Brain Research. 1348:187-199
Small conductance calcium (Ca(2+)) activated SK channels are critical regulators of neuronal excitability in hippocampus. Accordingly, these channels are thought to play a key role in controlling neuronal activity in acute models of epilepsy. In this
Autor:
Carlos Fernando Mello, Leonardo Magno Rambo, Luis F. Pacheco Otalora, Juliano Ferreira, Leandro Rodrigo Ribeiro, Ana Flávia Furian, João B. Calixto, Emilio Rafael Garrido-Sanabria, Luiz Fernando Freire Royes, Mauro Schneider Oliveira
Publikováno v:
Journal of Neurochemistry. 109:416-426
Prostaglandin E(2) (PGE(2)) is quantitatively one of the major prostaglandins synthesized in mammalian brain, and there is evidence that it facilitates seizures and neuronal death. However, little is known about the molecular mechanisms involved in s
Autor:
Emilio R. Garrido-Sanabria, Massoud F. Arshadmansab, Boris Ermolinsky, Luis F. Pacheco Otalora, Masoud M. Zarei
Publikováno v:
Brain Research. 1226:173-180
Group II metabotropic glutamate (mGlu II) receptors subtype 2 and 3 (mGlu2 and mGlu3) are subtle regulators of neuronal excitability and synaptic plasticity in the hippocampus. In recent years, researchers have investigated the potential neuroprotect
Autor:
Emilio R. Garrido-Sanabria, Boris Ermolinsky, Luis F. Pacheco Otalora, Masoud M. Zarei, Michael Willis, Massoud F. Arshadmansab, Eder F. Hernandez, Sebastian Francisco, Hans-Guenther Knaus
Publikováno v:
Brain Research. 1200:116-131
In the hippocampus, BK channels are preferentially localized in presynaptic glutamatergic terminals including mossy fibers where they are thought to play an important role regulating excessive glutamate release during hyperactive states. Large conduc
Publikováno v:
Brain Research. 1144:219-230
The dipeptide N-acetylaspartylglutamate (NAAG) has been recently implicated in numerous neurological disorders. NAAG binds and stimulates group II metabotropic glutamate receptors producing a down-modulation of synaptic glutamate release. In the pres
Autor:
Bianca Farrell, Tarun Pandari, Boris Ermolinsky, Carlos Fernando Mello, Frank Skinner, Luis F. Pacheco Otalora, Mauro Schneider Oliveira, Ileana Garcia, Massoud F. Arshadmansab, Emilio R. Garrido-Sanabria, Leslie Robles, Gerardo Rosas
Publikováno v:
Brain research. 1368
Voltage gated K+ channels (Kv) are a highly diverse group of channels critical in determining neuronal excitability. Deficits of Kv channel subunit expression and function have been implicated in the pathogenesis of epilepsy. In this study, we invest
Autor:
Luis F. Pacheco Otalora, Emilio R. Garrido-Sanabria, Masoud M. Zarei, Boris Ermolinsky, Massoud F. Arshadmansab
Publikováno v:
Neuroreport. 19(13)
Epileptogenesis in mesial temporal lobe epilepsy is determined by several factors including abnormalities in the expression and function of ion channels. Here, we report a long-lasting deficit in gene expression of Kcnma1 coding for the large-conduct