Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Luis F de Castro"'
Autor:
Luis F. de Castro, Jarred M. Whitlock, Zachary Michel, Kristen Pan, Jocelyn Taylor, Vivian Szymczuk, Brendan Boyce, Daniel Martin, Vardit Kram, Rebeca Galisteo, Kamran Melikov, Leonid V. Chernomordik, Michael T. Collins, Alison M. Boyce
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Fibrous dysplasia (FD) is a rare, disabling skeletal disease for which there are no established treatments. Growing evidence supports inhibiting the osteoclastogenic factor receptor activator of nuclear kappa-B ligand (RANKL) as a potential
Externí odkaz:
https://doaj.org/article/66f8de75dbf240338687f4e6e2682696
Autor:
Diana Ovejero, Zachary Michel, Christophe Cataisson, Amanda Saikali, Rebeca Galisteo, Stuart H. Yuspa, Michael T. Collins, Luis F. de Castro
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Cutaneous skeletal hypophosphatemia syndrome (CSHS) is a mosaic RASopathy characterized by the association of dysplastic skeletal lesions, congenital skin nevi of epidermal and/or melanocytic origin, and FGF23-mediated hypophosphatemia. The primary p
Externí odkaz:
https://doaj.org/article/7f8e170ae61a40e38c63ea6074cc6fde
Autor:
Jarred M. Whitlock, Luis F. de Castro, Michael T. Collins, Leonid V. Chernomordik, Alison M. Boyce
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106470- (2023)
Summary: Elucidating a basic blueprint of osteoclast-osteoblast coordination in skeletal remodeling and understanding how this coordination breaks down with age and disease is essential for addressing the growing skeletal health problem in our aging
Externí odkaz:
https://doaj.org/article/41e47cbf2475412a8a4b8000d9ae1202
Autor:
Kelly L. Roszko, Lori Guthrie, Xiaobai Li, Michael T. Collins, Luis F. de Castro, Alison M. Boyce
Publikováno v:
Journal of Bone and Mineral Research. 38:443-450
Autor:
Iris R. Hartley, Rachel I. Gafni, Kelly L. Roszko, Sydney M. Brown, Luis F. de Castro, Amanda Saikali, Carlos R. Ferreira, William A. Gahl, Karel Pacak, Jenny E. Blau, Alison M. Boyce, Isidro B. Salusky, Michael T. Collins, Pablo Florenzano
Publikováno v:
Journal of Bone and Mineral Research. 37:2174-2185
Fibroblast growth factor-23 (FGF23) measurement is a critical tool in the evaluation of patients with disordered phosphate homeostasis. Available laboratory reference ranges for blood FGF23 were developed using samples from normophosphatemic individu
Autor:
Luis F. de Castro, Zachary Michel, Kristen Pan, Jocelyn Taylor, Vivian Szymczuk, Sriram Paravastu, Babak Saboury, Georgios Z. Papadakis, Xiaobai Li, Kelly Milligan, Brendan Boyce, Scott M. Paul, Michael T. Collins, Alison M. Boyce
Publikováno v:
New England Journal of Medicine. 388:766-768
Autor:
Kelly L, Roszko, Lori, Guthrie, Xiaobai, Li, Michael T, Collins, Luis F, de Castro, Alison M, Boyce
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
Fibrous dysplasia/McCune-Albright syndrome (FD/MAS) is a rare mosaic bone and endocrine disorder. While most variants affect the GNAS R201 codon, obtaining a genetic diagnosis is difficult because not all cells harbor the variant, and an invasive bio
Autor:
Jarred M. Whitlock, Luis F. de Castro, Michael T. Collins, Leonid V. Chernomordik, Alison M. Boyce
Metabolic bone diseases are a collection of disorders resulting in diminished skeletal integrity and changes in bone mass due to perturbations in the life-long process of bone remodeling. Perturbations in the number, size and nuclear multiplicity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9be41e9e57c30773fe2616fd77a41031
https://doi.org/10.1101/2022.10.27.514052
https://doi.org/10.1101/2022.10.27.514052
Autor:
Luis F de Castro, Jarred M Whitlock, Zachary Michel, Kristen Pan, Jocelyn Taylor, Vivian Szymczuk, Sriram S Paravastu, Babak Saboury, Georgios Z Papadakis, Leonid V Chernomordik, Xiaobai Li, Kelly Milligan, Brendan Boyce, Scott Paul, Daniel Martin, Michael T Collins, Alison M Boyce
BACKGROUNDFibrous dysplasia (FD) is a rare, disabling disease with no established treatments. Growing evidence supports inhibiting the pro-osteoclastic factor receptor activator of nuclear Kappa-B ligand (RANKL) as a potential treatment strategy. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6122bcc7ba41c8e0d98f47e640f2e222
https://doi.org/10.1101/2022.10.24.22281375
https://doi.org/10.1101/2022.10.24.22281375