Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Luis F Hernandez"'
1
Akademický článek
A machine learning approach to predict pancreatic islet grafts rejection versus tolerance.
Autor: Gerardo A Ceballos, Luis F Hernandez, Daniel Paredes, Luis R Betancourt, Midhat H Abdulreda
Publikováno v: PLoS ONE, Vol 15, Iss 11, p e0241925 (2020)
The application of artificial intelligence (AI) and machine learning (ML) in biomedical research promises to unlock new information from the vast amounts of data being generated through the delivery of healthcare and the expanding high-throughput res
Externí odkaz: https://doaj.org/article/b5c0488680614f5780bf44f63b4ffb99
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2
Akademický článek
Feasibility of Localized Metabolomics in the Study of Pancreatic Islets and Diabetes
Autor: Oscar Alcazar, Luis F. Hernandez, Ashley Tschiggfrie, Michael J. Muehlbauer, James R. Bain, Peter Buchwald, Midhat H. Abdulreda
Publikováno v: Metabolites, Vol 9, Iss 10, p 207 (2019)
(1) Background: Disruption of insulin production by native or transplanted pancreatic islets caused by auto/allo-immunity leads to hyperglycemia, a serious health condition and important therapeutic challenge due to the lifelong need for exogeneous i
Externí odkaz: https://doaj.org/article/a79d3ffa6b1a4502a515cc736b53794e
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3
Anti-Oxidative Therapy in Diabetic Nephropathy
Autor: Hirohito Ichii, Ekamol Tantisattamo, Michael Alexander, David Whaley, Natsuki Eguchi, Luis F. Hernandez
Publikováno v: Frontiers in bioscience (Scholar edition). 14(2)
Chronic kidney disease is generally progressive and currently has no reliable treatment to reverse a decline in kidney function or to slow the progression of the disease. Diabetic nephropathy is one of the leading causes of end-stage kidney failure.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f056a385bdcf7859d7b058ff45609c
https://pubmed.ncbi.nlm.nih.gov/35730439
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4
Dysregulation of β-Cell Proliferation in Diabetes: Possibilities of Combination Therapy in the Development of a Comprehensive Treatment
Autor: Natsuki Eguchi, Arvin John Toribio, Michael Alexander, Ivana Xu, David Lee Whaley, Luis F. Hernandez, Donald Dafoe, Hirohito Ichii
Publikováno v: Biomedicines. 10(2)
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia as a result of insufficient insulin levels and/or impaired function as a result of autoimmune destruction or insulin resistance. While Type 1 DM (T1DM) and Type 2 D
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f112620c7bbbbcaad6624340109c424
https://pubmed.ncbi.nlm.nih.gov/35203680
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5
Multisensory Integration: Is Medial Prefrontal Cortex Signaling Relevant for the Treatment of Higher-Order Visual Dysfunctions?
Autor: Miguel Skirzewski, Stéphane Molotchnikoff, Luis F. Hernandez, José Fernando Maya-Vetencourt
Publikováno v: Frontiers in Molecular Neuroscience, Vol 14 (2022)
Frontiers in Molecular Neuroscience
In the mammalian brain, information processing in sensory modalities and global mechanisms of multisensory integration facilitate perception. Emerging experimental evidence suggests that the contribution of multisensory integration to sensory percept
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2217664069fbee2b54fc35e0637da7
https://www.frontiersin.org/articles/10.3389/fnmol.2021.806376/full
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7
Parallel Multi-Omics in High-Risk Subjects for the Identification of Integrated Biomarker Signatures of Type 1 Diabetes
Autor: Peter Buchwald, Ciara Myer, Midhat H. Abdulreda, Luis F. Hernandez, Charles Ansong, Oscar Alcazar, Michael J. Muehlbauer, Ernesto S. Nakayasu, Sanjoy K. Bhattacharya, James R. Bain, Carrie D. Nicora
Publikováno v: Biomolecules
Volume 11
Issue 3
Biomolecules, Vol 11, Iss 383, p 383 (2021)
Background: Biomarkers are crucial for detecting early type-1 diabetes (T1D) and preventing significant β-cell loss before the onset of clinical symptoms. Here, we present proof-of-concept studies to demonstrate the potential for identifying integra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52860a13c6be314a6010826ed6eadc30
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9
Micellar electrokinetic chromatography with laser induced fluorescence detection shows increase of putrescine in erythrocytes of Parkinson's disease patients
Autor: P. Tucci, L.E. Hernandez, Hilarión Araujo, M. De Pasquale, Z. Mari, Luis F. Hernandez, Pedro Rada, L. Betancourt, Daniel Paredes, Gerardo Ceballos
Publikováno v: Journal of Chromatography B. :51-57
A highly sensitive method was developed to measure putrescine by micellar electrokinetic chromatography with laser induced fluorescence detection with excellent linearity in the 1 nM to 3 μM range. The technique was tested on a drop of blood from Pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8f9132e8169f4537ee9b11689205ab
https://doi.org/10.1016/j.jchromb.2018.02.015
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10
Integrated Metabolomics and Proteomics Analyses in the Local Milieu of Islet Allografts in Rejection versus Tolerance
Autor: L. Betancourt, Charles Ansong, Daniel Paredes, Midhat H. Abdulreda, Gerardo Ceballos, Ernesto S. Nakayasu, Luis F. Hernandez
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 8754, p 8754 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
An understanding of the immune mechanisms that lead to rejection versus tolerance of allogeneic pancreatic islet grafts is of paramount importance, as it facilitates the development of innovative methods to improve the transplant outcome. Here, we us
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bebd673fc123aa1eddf6ed10c0f87c
https://doi.org/10.3390/ijms22168754
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