Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Luis F, Callado"'
Autor:
Jon DelaCuesta-Barrutia, Oihane Martínez-Peula, Guadalupe Rivero, Jon A. Santas-Martín, Eva Munarriz-Cuezva, Iria Brocos-Mosquera, Patricia Miranda-Azpiazu, Rebeca Diez-Alarcia, Benito Morentin, William G. Honer, Luis F. Callado, Amaia M. Erdozain, Alfredo Ramos-Miguel
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Antipsychotic-induced low availability of group II metabotropic glutamate receptors (including mGlu2R and mGlu3R) in brains of schizophrenia patients may explain the limited efficacy of mGlu2/3R ligands in clinical trials. Studies evaluating
Externí odkaz:
https://doaj.org/article/5c2c7314bce1491f9eb0e77df95c3820
Autor:
Bohan Zhu, Richard I Ainsworth, Zengmiao Wang, Zhengzhi Liu, Salvador Sierra, Chengyu Deng, Luis F Callado, J Javier Meana, Wei Wang, Chang Lu, Javier González-Maeso
Publikováno v:
eLife, Vol 12 (2024)
Genome-wide association studies have revealed >270 loci associated with schizophrenia risk, yet these genetic factors do not seem to be sufficient to fully explain the molecular determinants behind this psychiatric condition. Epigenetic marks such as
Externí odkaz:
https://doaj.org/article/3d93059727454ba289151c44ddd8e836
Autor:
Anusha W. Mudyanselage, Buddhika C. Wijamunige, Artur Kocoń, Ricky Turner, Denise McLean, Benito Morentin, Luis F. Callado, Wayne G. Carter
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 580 (2024)
Alcohol is toxic to neurons and can trigger alcohol-related brain damage, neuronal loss, and cognitive decline. Neuronal cells may be vulnerable to alcohol toxicity and damage from oxidative stress after differentiation. To consider this further, the
Externí odkaz:
https://doaj.org/article/d118e697237a4f46bd1a9ba5132819ff
Autor:
Cristina Lorca, María Fernández-Rhodes, Jose Antonio Sánchez Milán, María Mulet, Félix Elortza, Alfredo Ramos-Miguel, Luis F. Callado, J. Javier Meana, Maria Mur, Iolanda Batalla, Elisabet Vilella, Aida Serra, Xavier Gallart-Palau
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 129 (2024)
Extracellular vesicles (EVs) are tiny membranous structures that mediate intercellular communication. The role(s) of these vesicles have been widely investigated in the context of neurological diseases; however, their potential implications in the ne
Externí odkaz:
https://doaj.org/article/bd4c98dd63eb4a2f91b36ed60762a094
Autor:
Andrea Bagán, Sergio Rodriguez-Arévalo, Teresa Taboada-Jara, Christian Griñán-Ferré, Mercè Pallàs, Iria Brocos-Mosquera, Luis F. Callado, José A. Morales-García, Belén Pérez, Caridad Diaz, Rosario Fernández-Godino, Olga Genilloud, Milan Beljkas, Slavica Oljacic, Katarina Nikolic, Carmen Escolano
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2381 (2023)
Humanity is facing a vast prevalence of neurodegenerative diseases, with Alzheimer’s disease (AD) being the most dominant, without efficacious drugs, and with only a few therapeutic targets identified. In this scenario, we aim to find molecular ent
Externí odkaz:
https://doaj.org/article/8035d4f3e12a4d57a2a19922f86e678f
Autor:
Iria Brocos-Mosquera, Patricia Miranda-Azpiazu, Carolina Muguruza, Virginia Corzo-Monje, Benito Morentin, J. Javier Meana, Luis F. Callado, Guadalupe Rivero
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Postsynaptic α2A-adrenoceptor density is enhanced in the dorsolateral prefrontal cortex (DLPFC) of antipsychotic-treated schizophrenia subjects. This alteration might be due to transcriptional activation, and could be regulated by epigeneti
Externí odkaz:
https://doaj.org/article/b8db53681558470383aa2e9e41a42f88
Autor:
Rebeca Diez-Alarcia, Carolina Muguruza, Guadalupe Rivero, Aintzane García-Bea, Vanessa Gómez-Vallejo, Luis F. Callado, Jordi Llop, Abraham Martín, J. Javier Meana
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The status of serotonin 5HT2A receptors (5HT2ARs) in schizophrenia has been controversial. In vivo positron emission tomography neuroimaging and in vitro post-mortem binding studies have reported conflicting results about 5HT2AR densit
Externí odkaz:
https://doaj.org/article/ab7a5744879b4c13a57c83edf01eeb7b
Autor:
Amaia Nuñez-delMoral, Paula C. Bianchi, Iria Brocos-Mosquera, Augusto Anesio, Paola Palombo, Rosana Camarini, Fabio C. Cruz, Luis F. Callado, Vincent Vialou, Amaia M. Erdozain
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 234 (2023)
Astrocytic-secreted matricellular proteins have been shown to influence various aspects of synaptic function. More recently, they have been found altered in animal models of psychiatric disorders such as drug addiction. Hevin (also known as Sparc-lik
Externí odkaz:
https://doaj.org/article/df1311d0f5384142a20fc43cc32959b2
Autor:
Yuji Odagaki, Masaki Mikami, Masakazu Kinoshita, J. Javier Meana, Luis F. Callado, Jesús A. García-Sevilla, Dasiel Oscar Borroto-Escuela, Kjell Fuxe
Publikováno v:
Pharmacological Reports. 75:266-275
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2977cf8dd37e5c7576cc7eaf7b8f98e
https://doi.org/10.1007/s43440-023-00448-6
https://doi.org/10.1007/s43440-023-00448-6
Autor:
Inés Ibarra-Lecue, Rebeca Diez-Alarcia, Benito Morentin, J. Javier Meana, Luis F. Callado, Leyre Urigüen
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The mechanistic target of rapamycin (also known as mammalian target of rapamycin) (mTOR)-dependent signaling pathway plays an important role in protein synthesis, cell growth, and proliferation, and has been linked to the development of the central n
Externí odkaz:
https://doaj.org/article/b1b5ae7dfa0d44109ae0b30e6289550f