Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Luis Espinoza-Catalán"'
Unexpected discovery: 'A new 3,3′-bipyrazolo[3,4-b]pyridine scaffold and its comprehensive analysis'
Autor:
Efraín Polo-Cuadrado, Karoll Ferrer, Jesús Sánchez-Márquez, Andrés Charris-Molina, Yeray A. Rodríguez-Núñez, Luis Espinoza-Catalán, Margarita Gutiérrez
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32573- (2024)
In this study, a novel 3,3′-bipyrazolo [3,4-b]pyridine-type structure was synthesized from 5-acetylamino-3-methyl-1-phenylpyrazole using the Vilsmeier-Haack reaction as a key step. The spectroscopic properties and structural elucidation of the comp
Externí odkaz:
https://doaj.org/article/577ecfbb28914c37be3ce32cfdbb44bc
Autor:
Sebastián Jorquera, Mauricio Soto, Katy Díaz, María Nuñez, Mauricio A. Cuellar, Andrés F. Olea, Luis Espinoza-Catalán
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7515 (2024)
Brassinosteroids (BRs) are an important group of polyhydroxylated naturally occurring steroidal phytohormones found in the plant kingdom in extremely low amounts. Due to the low concentrations in which these compounds are found, much effort has been
Externí odkaz:
https://doaj.org/article/00ac52208cb54f75a16a87dc398b1aca
Autor:
Iván Montenegro, Rolando Pazmiño, Ileana Araque, Alejandro Madrid, Ximena Besoain, Enrique Werner, Luis Espinoza-Catalán, Andrés F. Olea, Claudio Parra, Valentina Navarrete Molina, Patricio Godoy, Yusser Olguín, Mauricio A. Cuellar
Publikováno v:
Molecules, Vol 29, Iss 12, p 2844 (2024)
In this work, a group of ten sesquiterpene drimanes, including polygodial (1), isopolygodial (2), and drimenol (3) obtained from the bark of Drimys winteri F. and seven synthetic derivatives, were tested in vitro against a unique panel of bacteria, f
Externí odkaz:
https://doaj.org/article/6ceea29d74694193a9ecff035bf293e4
Autor:
Mauricio Enrique Osorio-Olivares, Yesseny Vásquez-Martínez, Katy Díaz, Javiera Canelo, Lautaro Taborga, Luis Espinoza-Catalán
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5999 (2024)
Flavonoids are an abundant class of naturally occurring compounds with broad biological activities, but their limited abundance in nature restricts their use in medicines and food additives. Here we present the synthesis and determination of the anti
Externí odkaz:
https://doaj.org/article/6efc1c58bb0d49cbbe65bacb4762a912
Autor:
Vanessa Aitken, Katy Diaz, Mauricio Soto, Andrés F. Olea, Mauricio A. Cuellar, Maria Nuñez, Luis Espinoza-Catalán
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 419 (2023)
The synthesis and biological evaluation of brassinosteroids (BRs) analogs with chemical modification in the side alkyl chain is a matter of current interest. Recently, a series of BR analogs with phenyl or benzoate groups in the alkyl chain have been
Externí odkaz:
https://doaj.org/article/ef5e25fb1fda4a3c9508308dbd5ee18d
Autor:
Mauricio Cuellar Fritis, Valentina Ulloa Valdivia, Joan Villena García, Cristóbal Carrasco Rojas, Luis Espinoza Catalán, Cristian Salas Sánchez, Iván Montenegro Venegas, Natalia Quiñones Sobarzo
Publikováno v:
Molecules, Vol 18, Iss 5, Pp 5517-5530 (2013)
The synthesis of a newangular analog 11 of cyclozonarone was achieved via Diels-Alder reaction between a sesquiterpene-1,3-diene and 1,4-benzoquinone. The cytotoxic activity of ent-cyclozonarone [(+)-10] and the angular (−)-cyclozonarone analog 11
Externí odkaz:
https://doaj.org/article/a61d8ebf23c24a8fab4dfd9aca7cee7a
New Catechol Derivatives of Safrole and Their Antiproliferative Activity towards Breast Cancer Cells
Autor:
Héctor Carrasco Altamirano, Joan Villena García, Luis Espinoza Catalán, Iván Montenegro Venegas, Alejandro Madrid Villegas
Publikováno v:
Molecules, Vol 16, Iss 6, Pp 4632-4641 (2011)
Catechols were synthesized from safrole. Nine derivatives were prepared and assessed for antiproliferative effects using different human cell lines. The in vitro growth inhibition assay was based on the sulphorhodamine dye to quantify cell viability.
Externí odkaz:
https://doaj.org/article/36a780f7041d43d4b47ceb0e789fb534
Autor:
Mauricio Cuellar Fritis, Joan Villena García, Mauricio Osorio Olivares, Héctor Carrasco Altamirano, Karen Catalán Marín, Evelyn Baeza Maturana, Luis Espinoza Catalán
Publikováno v:
Molecules, Vol 15, Iss 9, Pp 6502-6511 (2010)
Two new compounds 2β-acetoxy-15-phenyl-(22,25-acetoxy)-ent-labda-8(17), 13(E)-diene (9) and 2β-hydroxy-15-phenyl-(22,24,26-trimethoxy)-ent-labda-8(17),13(E)-diene (10) have been prepared by an Electrophilic Aromatic Substitution (EAS) reaction betw
Externí odkaz:
https://doaj.org/article/2e6edb70e06e4a7989079e26a1f344c7
Autor:
Natalia Quiñones, Santiago Hernández, Luis Espinoza Catalán, Joan Villena, Ivan Brito, Alan R. Cabrera, Cristian O. Salas, Mauricio A. Cuellar
Publikováno v:
Molecules, Vol 23, Iss 6, p 1422 (2018)
We describe the syntheses of nine new angucyclinone 6-aza-analogues, achieved through a hetero Diels-Alder reaction between the shikimic acid derivative-azadiene 13, with different naphthoquinones. The cytotoxic activity of the new synthesized compou
Externí odkaz:
https://doaj.org/article/41864fbf33134dc795dbc131c675fde5
Autor:
Mauricio Cuellar Fritis, Joan Villena García, Luis Espinoza Catalán, Héctor Carrasco Altamirano, Alejandro Madrid Villegas, Karen Catalán Marín
Publikováno v:
Molecules, Vol 14, Iss 6, Pp 2181-2194 (2009)
The synthesis and structural determination of two new diterpenylhydroquinones: 2β-acetoxy-15-phenyl-(22,25-dihydroxy)-ent-labda-8(17),13(E)-diene(1) and 2β-hydroxy-15-phenyl-(22,25-dihydroxy)-ent-labda-8(17),13(E)-dieneis reported (2). These compou
Externí odkaz:
https://doaj.org/article/adea006d803440729afe0c9d75980a56