The influence of Na+,K+-ATPase on glutamate signaling in neurodegenerative diseases and senescence

Autor: Paula Fernanda Kinoshita, Jacqueline Alves Leite, Ana Maria Marques Orellana, Andrea Rodrigues Vasconcelos, Luis Eduardo M Quintas, Elisa Mitiko Kawamoto, Cristoforo eScavone

Publikováno v: Frontiers in Physiology, Vol 7 (2016)

Decreased Na+,K+-ATPase (NKA) activity causes energy deficiency, which is commonly observed in neurodegenerative diseases. The NKA is constituted of three subunits: α, β and γ, with four distinct isoforms of the catalytic α subunit (α1-4). Genet

Externí odkaz: https://doaj.org/article/06fa27ff105c41a79529f428e56b0d0a

A Novel Apilic Antivenom to Treat Massive, Africanized Honeybee Attacks: A Preclinical Study from the Lethality to Some Biochemical and Pharmacological Activities Neutralization

Autor: Jhonatha Mota Teixeira-Cruz, Marcelo Abrahão Strauch, Marcos Monteiro-Machado, Matheus Silva Tavares-Henriques, João Alfredo de Moraes, Luís Eduardo Ribeiro da Cunha, Rui Seabra Ferreira, Benedito Barraviera, Luis Eduardo M. Quintas, Paulo A. Melo

Publikováno v: Toxins, Vol 13, Iss 1, p 30 (2021)

Massive, Africanized honeybee attacks have increased in Brazil over the years. Humans and animals present local and systemic effects after envenomation, and there is no specific treatment for this potentially lethal event. This study evaluated the ab

Externí odkaz: https://doaj.org/article/803f6d5e902344669ec50fa576fdd110

Isoproterenol induces an increase in muscle fiber size by the proliferation of Pax7‐positive cells and in a mTOR‐independent mechanism

Autor: Claudia Mermelstein, Manoel L. Costa, Graciele Gonçalves, John Douglas de Oliveira Teixeira, Luis Eduardo M. Quintas, Ivone de Andrade Rosa, Úrsula Maria C Bastos

Publikováno v: Cell Biology International

β‐Adrenergic signaling regulates many physiological processes in skeletal muscles. A wealth of evidence has shown that β‐agonists can increase skeletal muscle mass in vertebrates. Nevertheless, to date, the specific role of β‐adrenergic rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12d70bcd0a3fb862b68eb675fc4ed5e
http://europepmc.org/articles/PMC6900101

Influence of Nitric Oxide-Cyclic GMP and Oxidative STRESS on Amyloid-β Peptide Induced Decrease of Na,K-ATPase Activity in Rat Hippocampal Slices

Autor: Luis Eduardo M. Quintas, Paula Fernanda Kinoshita, M. M. Cararo-Lopes, Cristoforo Scavone, Diana Zukas Andreotti, Larissa de Sá Lima, Elisa Mitiko Kawamoto

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Amyloid-β peptide (Aβ) has been shown to cause synaptic dysfunction and can render neurons vulnerable to excitotoxicity and oxidative stress. Na,K-ATPase plays an important role to maintain cell ionic equilibrium and it can be modulated by N-methyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b04bd63c951b009d5997d0f692c3d6
https://pubmed.ncbi.nlm.nih.gov/34327545

A Novel Apilic Antivenom to Treat Massive, Africanized Honeybee Attacks: A Preclinical Study from the Lethality to Some Biochemical and Pharmacological Activities Neutralization

Autor: João Alfredo Moraes, Luís Eduardo Ribeiro da Cunha, Marcos Monteiro-Machado, Rui Seabra Ferreira, Paulo A. Melo, Benedito Barraviera, Matheus Da Silva Tavares-Henriques, Jhonatha Da Mota Teixeira-Cruz, Luis Eduardo M. Quintas, Marcelo A. Strauch

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Toxins, Vol 13, Iss 30, p 30 (2021)
Toxins
Volume 13
Issue 1

Massive, Africanized honeybee attacks have increased in Brazil over the years. Humans and animals present local and systemic effects after envenomation, and there is no specific treatment for this potentially lethal event. This study evaluated the ab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3777bd498fac3219a2457872b60040d9