Zobrazeno 1 - 10 of 83 pro vyhledávání: '"Luis Chacón García"'
1
Akademický článek
Synthesis of the 1,5-disubstituted tetrazole-methanesulfonylindole hybrid system via high-order multicomponent reaction
Autor: Cesia M. Aguilar-Morales, América A. Frías-López, Nadia V. Emilio-Velázquez, Alejandro Islas-Jácome, Angelica Judith Granados-López, Jorge Gustavo Araujo-Huitrado, Yamilé López-Hernández, Hiram Hernández-López, Luis Chacón-García, Jesús Adrián López, Carlos J. Cortés-García
Publikováno v: Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 3077-3084 (2024)
A series of 1,5-disubstituted tetrazole-indole hybrids were synthesized via a high-order multicomponent reaction consisting of an Ugi-azide/Pd/Cu-catalyzed hetero-annulation cascade sequence. This operationally simple one-pot protocol allowed high bo
Externí odkaz: https://doaj.org/article/005fa626141148e0962b0b132ff09bad
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2
Akademický článek
Proliferation, Migration and Invasion of Breast Cancer Cell Lines Are Inhibited by 1,5-Disubstituted Tetrazol-1,2,3-triazole Hybrids through Interaction with p53
Autor: Marisol Moreno-Perea, Abel Suárez-Castro, Ixamail Fraire-Soto, Jessica Lizbeth Sifuentes-Padilla, Rosalinda Gutiérrez-Hernández, Claudia Araceli Reyes-Estrada, Yamilé López-Hernández, Carlos J. Cortés-García, Luis Chacón-García, Angelica Judith Granados-López, Jesús Adrián López
Publikováno v: Molecules, Vol 28, Iss 22, p 7600 (2023)
The anticarcinogenic potential of a series of 1,5-disubstituted tetrazole-1,2,3-triazole hybrids (T-THs) was evaluated in the breast cancer (BC)-derived cell lines MCF-7 (ER+, PR+, and HER2−), CAMA-1 (ER+, PR+/−, and HER2−), SKBR-3 (ER+, PR+, a
Externí odkaz: https://doaj.org/article/9453bf2f32b549a8af2cb93562661516
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5
Akademický článek
Semisynthesis of 6β-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction
Autor: Gabriela Servín-García, Luis Chacón-García, Joaquín González-Marrero, Mariana Macías-Alonso, Mario A. Gómez-Hurtado, Gabriela Rodríguez-García, Rosa E. del Río, Carlos J. Cortés-García
Publikováno v: Chemistry Proceedings, Vol 12, Iss 1, p 24 (2022)
A semisynthesis of 6β-acetoxyvouacapane-1,5-disusbtituted tetrazoles derivatives from the leaves of Caesalpinia platyloba by using the Ugi-azide multicomponent reaction as a key step reaction is described. To our knowledge, this is the first report
Externí odkaz: https://doaj.org/article/9d997e3725a945e4a47e97aa2d3fb1f5
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6
Akademický článek
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7
Akademický článek
Tackling the SARS-CoV-2 main protease using hybrid derivatives of 1,5-disubstituted tetrazole-1,2,3-triazoles: an in silico assay
Autor: Carlos J. Cortés-García, Luis Chacón-García, Jorge Emmanuel Mejía-Benavides, Erik Díaz-Cervantes
Publikováno v: PeerJ Physical Chemistry, Vol 2, p e10 (2020)
In regard to the actual public health global emergency and, based on the state of the art about the ways to inhibit the SARS-CoV-2 treating the COVID19, a family of 1,5-disubstituted tetrazole-1,2,3-triazoles, previously synthesized, have been evalua
Externí odkaz: https://doaj.org/article/2f6077e05b344fe28361e8e0ee153ad7
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8
Akademický článek
A One-Pot Six-Component Reaction for the Synthesis of 1,5-Disubstituted Tetrazol-1,2,3-Triazole Hybrids and Their Cytotoxic Activity against the MCF-7 Cell Line
Autor: Cesia M. Aguilar-Morales, Jorge Gustavo Araujo-Huitrado, Yamilé López-Hernández, Claudia Contreras-Celedón, Alejandro Islas-Jácome, Angelica Judith Granados-López, Cesar R. Solorio-Alvarado, Jesús Adrián López, Luis Chacón-García, Carlos J. Cortés-García
Publikováno v: Molecules, Vol 26, Iss 20, p 6104 (2021)
A high-order multicomponent reaction involving a six-component reaction to obtain the novel linked 1,5-disubstituted tetrazole-1,2,3-triazole hybrids in low to moderate yield is described. This one-pot reaction is carried out under a cascade process
Externí odkaz: https://doaj.org/article/5794eea403eb472db114e93ff29d57b5
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9
Akademický článek
Synthesis of Hybrid Fluoroquinolone-Boron Complexes and Their Evaluation in Cervical Cancer Cell Lines
Autor: Hiram Hernández-López, Griselda Sánchez-Miranda, Jorge Gustavo Araujo-Huitrado, Angelica Judith Granados-López, Jesús Adrián López, Socorro Leyva-Ramos, Luis Chacón-García
Publikováno v: Journal of Chemistry, Vol 2019 (2019)
Quinolones are a family of antimicrobial agents that have been used in antibacterial and anticancer chemotherapy. Fluoroquinolone targets DNA gyrase and topoisomerase IV enzymes affecting several cellular processes, like cell death and proliferation;
Externí odkaz: https://doaj.org/article/29a9560706f048cdb3c4e278bf82924d
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10
Prediction of the impact induced by Cd in binary interactions with other divalent metals on wild-type and Cd-resistant strains of Dictyosphaerium chlorelloides
Autor: M. Carmen Bartolomé, S. Sánchez-Fortún, Ana Sánchez-Fortún, Luis Chacón-García, Martha Estrella García-Pérez, Alondra A. Cortés Téllez
Publikováno v: Environmental Science and Pollution Research. 29:22555-22565
The metals present in freshwater have a toxic profile with bioaccumulation and are biomagnified along the aquatic food chain. The metals induce high sensitivity in most aquatic organisms, while others, such as some microalgae species, evolve towards
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04970f147475e4724381f0af618e7159
https://doi.org/10.1007/s11356-021-17372-y
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