Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Luis C. Pena"'
Autor:
J Lai, Luis C. Pena, L. Berleau, Bruce Keyt, C Pater, J Ogez, C J Refino, Alice M. Chow, N F Paoni, Hung V. Nguyen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 91(9)
Current treatment with tissue plasminogen activator (tPA) requires an intravenous infusion (1.5-3 h) because the clearance of tPA from the circulation is rapid (t 1/2 approximately 6 min). We have developed a tPA variant, T103N,N117Q, KHRR(296-299)AA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b49fb3a4f0dddb5dc487a719699f5f
https://pubmed.ncbi.nlm.nih.gov/8170967
https://pubmed.ncbi.nlm.nih.gov/8170967
Autor:
Nicholas F. Paoni, Alice M. Chow, William F. Bennett, Luis C. Pena, Bruce Keyt, Mark J. Zoller
Publikováno v:
Protein engineering. 6(5)
The fibrin specificity of tissue-type plasminogen activator can be increased by mutagenesis within at least four sites in the protease domain. These sites include residue I276, the new N-terminus formed by conversion to a two-chain structure, residue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf515c647378589fb4ce344f273b5837
https://pubmed.ncbi.nlm.nih.gov/8415579
https://pubmed.ncbi.nlm.nih.gov/8415579
Autor:
Maria del Pilar Ramirez, Juan E. Restrepo, Luis V. Syro, Fabio Rotondo, Francisco J. Londoño, Luis C. Penagos, Humberto Uribe, Eva Horvath, Kalman Kovacs
Publikováno v:
Case Reports in Pathology, Vol 2012 (2012)
We report here the case of a 61-year-old woman who presented with hydrocephalus and cystic and solid lesions in sella turcica, suprasellar areas, and third ventricle. After ventriculoperitoneal shunt she developed cognitive changes and the cystic les
Externí odkaz:
https://doaj.org/article/d7f1c4fa74874af4989333b677906d1f