Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Luis C. Antón"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/f03a5a7b597e4a35a98b5e8f54a1ec72
Autor:
Patricia Martín-Maestro, Ricardo Gargini, Andrew A. Sproul, Esther García, Luis C. Antón, Scott Noggle, Ottavio Arancio, Jesús Avila, Vega García-Escudero
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Familial Alzheimer’s disease (FAD) is clearly related with the accumulation of amyloid-beta (Aβ) and its deleterious effect on mitochondrial function is well established. Anomalies in autophagy have also been described in these patients. In the pr
Externí odkaz:
https://doaj.org/article/15e4554227ef41ca914166f0045fb410
Publikováno v:
Current opinion in immunology. 64
Altered and infected cells are eliminated by CD8+ cytotoxic T lymphocytes. This requires production of antigenic peptides mostly in the cytosol, transport to the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcb8476f10a0586bf6f51918ed03d82
https://pubmed.ncbi.nlm.nih.gov/31935516
https://pubmed.ncbi.nlm.nih.gov/31935516
Autor:
Luis C. Antón, Jonathan W. Yewdell
Publikováno v:
Journal of Leukocyte Biology. 95:551-562
MHC class I molecules display oligopeptides on the cell surface to enable T cell immunosurveillance of intracellular pathogens and tumors. Speed is of the essence in detecting viruses, which can complete a full replication cycle in just hours, wherea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a344cfb9462dc1aae87083c6983d4ed
https://doi.org/10.1189/jlb.1113599
https://doi.org/10.1189/jlb.1113599
Autor:
Margarita Del Val, Luis C. Antón
Publikováno v:
Molecular Immunology. 113:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e605bf0fed1b35c61e63a05960368f02
https://doi.org/10.1016/j.molimm.2019.07.016
https://doi.org/10.1016/j.molimm.2019.07.016
Autor:
Eugenia M. Villasevil, Luis C. Antón
Publikováno v:
Biochemical Society Transactions. 36:839-842
While it is clear that the proteasome is the major player in degradative proteolysis in the nucleus and cytosol, there is a lack of complete agreement on whether there are alternative proteolytic pathways or activities responsible for a significant d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd6e14955f7a28db326055bca58c3fd
https://doi.org/10.1042/bst0360839
https://doi.org/10.1042/bst0360839
Autor:
Sara Guil, Francisco Aguilar, Eugenia M. Villasevil, Margarita Del Val, Marta Rodríguez-Castro, Luis C. Antón
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Instituto de Salud Carlos III (ISCIII)
CD8(+) T lymphocytes recognize infected cells that display virus-derived antigenic peptides complexed with major histocompatibility complex class I molecules. Peptides are mainly byproducts of cellular protein turnover by cytosolic proteasomes. Cytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0740ba9aa33c833c51cce56e16db9847
https://doi.org/10.1074/jbc.m608522200
https://doi.org/10.1074/jbc.m608522200
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Recognition of infected or altered cells by CD8+ cytotoxic T lymphocytes is mediated by direct interaction of their T-cell receptor with peptides presented by MHC class I molecules. Peptides are transferred for assembly with newly synthesized MHC mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b98ad659c75887eba7ea3fe2684f480
https://doi.org/10.1016/j.molimm.2012.10.018
https://doi.org/10.1016/j.molimm.2012.10.018
Autor:
Jack R. Bennink, James P. Gibbs, Ulrich S. Schubert, Luis C. Antón, Christopher C. Norbury, Jonathan W. Yewdell
Publikováno v:
Nature. 404:770-774
MHC class I molecules function to present peptides eight to ten residues long to the immune system. These peptides originate primarily from a cytosolic pool of proteins through the actions of proteasomes, and are transported into the endoplasmic reti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa02255873bc4e3edf2d6598e40a071
https://doi.org/10.1038/35008096
https://doi.org/10.1038/35008096
Publikováno v:
Immunity. 12:83-93
Following influenza virus infection, the numbers of mouse T CD8 + cells responding to five different determinants vary more than 50-fold in primary responses but less so in secondary responses. Surprisingly, each determinant elicits a highly diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153e962d72bd4288ca4c857cd49ce7cf
https://doi.org/10.1016/s1074-7613(00)80161-2
https://doi.org/10.1016/s1074-7613(00)80161-2