Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Luis Buelta"'
Autor:
Luis Buelta, Ramón Merino, Pilar Álvarez, Jorge Postigo, Jesús Merino, Marcos Iglesias, Juan Jesús Augustin
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
[Objective]: Transforming growth factor β (TGFβ) plays a prominent role in the establishment of immunologic tolerance, and mice lacking TGFβ1 die of multiorgan inflammation early in life. TGFβ controls the differentiation of CD4+ lymphocytes into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faeac191364dcd1e61d37855b0461666
http://hdl.handle.net/10261/164284
http://hdl.handle.net/10261/164284
Autor:
Maria Angeles Ramos, Angel-Luis Martin De Francisco, Luis Buelta, Celestino Piñera, Manuel Arias, Maria Angeles de Cos, Ramón Merino, M A Setién
Publikováno v:
Nephrology Dialysis Transplantation. 18:878-883
Background. Mycophenolate mofetil (MMF) has been successfully used to improve or prevent the development of systemic lupus erythematosus (SLE) in both humans and in several lupus-prone mice. In the present study, we evaluated mechanisms through which
Autor:
José Fernando Val-Bernal, María Carmen González-Vela, María Francisca Garijo, Fidel Fernández, Luis Buelta
Publikováno v:
Histopathology. 34:35-42
Aims To determinate the relationship between tumoral angiogenesis and cathepsin D (CD) expression in tumour and host stromal cells of invasive breast carcinoma, and to examine its association with classical prognostic factors such as lymph node statu
Autor:
M. Francisca Garijo, M. Carmen González-Vela, Luis Buelta, Fidel Fernández, J. Fernando Val-Bernal
Publikováno v:
Pathology - Research and Practice. 195:611-618
Summary The presence of axillary lymph node metastases (ALNMs) is the most important prognostic factor in breast carcinoma. If ALNMs were predictable without performing axillary lymph node dissection (ALND), this procedure would not be necessary in s
Autor:
Shozo Izui, Marcos López-Hoyos, Roberto Carrio, Ramón Merino, Luis Buelta, Jesús Merino, Gabriel Núñez
Publikováno v:
Journal of Experimental Medicine, Vol. 183, No 6 (1996) pp. 2523-2531
The Journal of Experimental Medicine
The Journal of Experimental Medicine
The bcl-2 protooncogene has been shown to provide a survival signal to self-reactive B cells, but it fails to override their developmental arrest after encounter with antigen. Furthermore, constitutive expression of bcl-2 in B cells does not promote
p27Kip1 inhibits systemic autoimmunity through the control of Treg cell activity and differentiation
Autor:
Ramón Merino, Inés Santiuste, Jorge Postigo, Marcos Iglesias, J. González, Esther Tamayo, Jesús Merino, Luis Buelta
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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[Objective]: Despite the importance of Treg cells in the maintenance of immunologic tolerance, the mechanisms that control their generation and activity are unknown. Since the cell cycle inhibitor p27Kip1 (p27) was involved in T cell anergy, we under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e979fa0e5522fab0258c4e38f7ed0c83
http://hdl.handle.net/10261/81665
http://hdl.handle.net/10261/81665
Autor:
Ramón Merino, José C. Rodríguez-Rey, Jorge Postigo, Fernanda Genre, Luis Buelta, Marcos Iglesias, Jesús Merino, Maigualida Tamara Fernández-Rey
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
El pdf del artículo es la versión pre-print.
[Objective]: To explore the bidirectional relationship between the development of rheumatoid arthritis (RA) and atherosclerosis using bovine type II collagen (CII)–immunized B10.RIII apoE−/− m
[Objective]: To explore the bidirectional relationship between the development of rheumatoid arthritis (RA) and atherosclerosis using bovine type II collagen (CII)–immunized B10.RIII apoE−/− m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4cf3ae1f2e6c2fad9c37e5bf51d279
http://hdl.handle.net/10261/49482
http://hdl.handle.net/10261/49482
Autor:
Marcos Iglesias, Ramón Merino, Shozo Izui, Inés Santiuste, Luis Buelta, Jesús Merino, Fernanda Genre, Francisco Mazorra
Publikováno v:
Journal of Autoimmunity, Vol. 35, No 4 (2010) pp. 316-324
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of autoimmunity
Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of autoimmunity
El pdf del artículo es la versión pre-print.-- et al.
Genetic abnormalities predisposing to autoimmunity generally act in a cooperative manner affecting one or several mechanisms regulating immunological tolerance. In addition, many of these g
Genetic abnormalities predisposing to autoimmunity generally act in a cooperative manner affecting one or several mechanisms regulating immunological tolerance. In addition, many of these g
Autor:
Marcial de la Hera, Jesús Merino, Jose Luis Alonso, Luis Buelta, Angeles Ramos, Vicente Rodriguez-Valverde, Antonio de la Hera
Publikováno v:
International Immunology. 4:67-74
BALB/c mice injected at birth with 10(8) semi-allogeneic (C57BL/6 x BALB.IgHb)F1 spleen cells develop a lupus-like syndrome in which autoantibodies bear exclusively the donor allotype. We have analyzed the evolution of donor B cell chimerism and the
Autor:
Mariá L. Sainz-Maza, Carlos Blanco, Fernando Val-Bernal, Fidel Fernández, Luis Buelta, Francisca Garijo
Publikováno v:
Renal Failure. 14:31-39
Experimental studies on mitomycin-C nephrotoxicity are scanty and mention the occurrence of cortical hemorrhage, tubular necrosis, or hydronephrosis secondary to papillomatous hyperplasia of the uroepithelium. To our knowledge, only one experimental