Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Luis Augusto Basso"'
Publikováno v:
International Journal of Mass Spectrometry. 302:12-18
The enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) catalyzes the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshikimate-3-phosphate, an intermediate in the shikimate pathway, which leads
Autor:
Diógenes Santiago Santos, Jaim S. Oliveira, Jose Henrique Pereira, Luis Augusto Basso, Walter Filgueira de Azevedo, Rafael Andrade Caceres, Igor B. Vasconcelos
Publikováno v:
Current Drug Targets. 8:459-468
Tuberculosis (TB) remains the leading cause of mortality due to a bacterial pathogen, Mycobacterium tuberculosis. However, no new classes of drugs for TB have been developed in the past 30 years. Therefore there is an urgent need to develop faster ac
Autor:
Luis Augusto Basso, Nelson José Freitas da Silveira, Walter Filgueira de Azevedo, Clarissa M. Czekster, Fernanda Canduri, Diógenes Santiago Santos, Marcio Vinicius Bertacine Dias, Mario Sergio Palma
Publikováno v:
Cell Biochemistry and Biophysics. 44:375-384
The development of new therapies against infectious diseases is vital in developing countries. Among infectious diseases, tuberculosis is considered the leading cause of death. A target for development of new drugs is the tryptophan pathway. The last
Autor:
Lucio Fillman, Bernardo Garicochea, Tiago Giulianni Lopes, Luis Augusto Basso, Daiana Renck, Eraldo L. Batista, Diógenes Santiago Santos, Silvana Lunardini, Vinicius Duval da Silva, Candida Deves, Henrique Fillman
Publikováno v:
Virchows Archiv : an international journal of pathology. 458(4)
The E-twenty-six (ETS) family of transcription factors is known to act as positive or negative regulators of the expression of genes that are involved in diverse biological processes, including those that control cellular proliferation, differentiati
Autor:
Júlio César Borges, Fernanda Ely, Carlos H.I. Ramos, Luis Augusto Basso, Fernanda Canduri, Walter Filgueira de Azevedo, Mario Sergio Palma, Marcio Vinicius Bertacine Dias, Diógenes Santiago Santos, Jeverson Frazzon, Jose Henrique Pereira
Publikováno v:
Journal of structural biology. 154(2)
In bacteria, fungi, plants, and apicomplexan parasites, the aromatics compounds, such as aromatics amino acids, are synthesized through seven enzymes from the shikimate pathway, which are absent in mammals. The absence of this pathway in mammals make