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pro vyhledávání: '"Luis Alicea"'
Autor:
Susan Salamone, Steven Tregay, Brian I. Bliss, Michael P. Trova, Simon Haydar, Joseph Anthony Bilotta, Luis Alicea, Patricia Snider, Matthew P. Rainka, R. Jason Herr, Xiaozhang Zheng, Denise Peace, Thuy Nguyen Duong, Keith D. Barnes, Travis Benanti, Thomas D. Friedrich, Matthew R. Johnson, Mark Bielaska, Yu Hui, John M. Lehman
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:6613-6617
The introduction of an aryl ring onto the 4-position of the C-6 benzyl amino group of the Cdk inhibitor roscovitine (2), maintained the potent Cdk inhibition demonstrated by roscovitine (2) as well as greatly improving the antiproliferative activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc9ed62ae30c61b43e5febf5164cc35
https://doi.org/10.1016/j.bmcl.2009.10.011
https://doi.org/10.1016/j.bmcl.2009.10.011
