Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Luis Alberto Baena-Lopez"'
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 4, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) have been proposed to play dual roles in cellular homeostasis, functioning both to remove unwanted intracellular molecules, and to enable communication between cells as a means of modulating cellular responses in
Externí odkaz:
https://doaj.org/article/cc16a53f25f5489aa66d203ffc742642
Autor:
Genevieve E. Melling, Ross Conlon, Paschalia Pantazi, Elizabeth R. Dellar, Priya Samuel, Luis Alberto Baena-Lopez, Jeremy C. Simpson, David R. F. Carter
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Assessing genuine extracellular vesicle (EV) uptake is crucial for understanding the functional roles of EVs. This study measured the bona fide labelling of EVs utilising two commonly used fluorescent dyes, PKH26 and C5-maleimide-Alexa633. M
Externí odkaz:
https://doaj.org/article/98e9895f1f47456f8da83233318a3928
Autor:
Elizabeth R. Dellar, Claire Hill, Genevieve E. Melling, David R.F Carter, Luis Alberto Baena‐Lopez
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 5, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) are a heterogeneous group of membrane‐enclosed structures produced by prokaryotic and eukaryotic cells. EVs carry a range of biological cargoes, including RNA, protein, and lipids, which may have both metabolic
Externí odkaz:
https://doaj.org/article/7cc7b7c6683449509dcbe59f9533511a
Autor:
Alessia Galasso, Derek Cui Xu, Claire Hill, Daria Iakovleva, Maria Irina Stefana, Luis Alberto Baena‐Lopez
Publikováno v:
Galasso, A, Xu, D C, Hill, C, Iakovleva, D, Stefana, M I & Baena-Lopez, L A 2023, ' Non-apoptotic caspase activation ensures the homeostasis of ovarian somatic stem cells ', EMBO Reports, vol. 2023, e51716 . https://doi.org/10.15252/embr.202051716
Current evidence has associated caspase activation with the regulation of basic cellular functions without causing apoptosis. Malfunction of non-apoptotic caspase activities may contribute to specific neurological disorders, metabolic diseases, autoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f525afe02b37f92f8be70905c47f53
https://pure.qub.ac.uk/en/publications/de175a9e-b724-4293-950c-5fad481053db
https://pure.qub.ac.uk/en/publications/de175a9e-b724-4293-950c-5fad481053db
Publikováno v:
The FEBS journalReferences.
Cell-cell communication is an essential aspect of multicellular life, key for coordinating cell proliferation, growth, and death in response to environmental changes. Whilst caspases are well-known for facilitating apoptotic and pyroptotic cell death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b685e7aab097a6618830bd15bc0345
https://pubmed.ncbi.nlm.nih.gov/35246932
https://pubmed.ncbi.nlm.nih.gov/35246932
Apoptosis is a major form of programmed cell death (PCD) that eliminates unnecessary and potentially dangerous cells in all metazoan organisms, thus ensuring tissue homeostasis and many developmental processes. Accordingly, defects in the activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4685edb169e53a904cbe00b75d7482
https://doi.org/10.1111/febs.15547
https://doi.org/10.1111/febs.15547
Autor:
Alessia Galasso, Luis Alberto Baena-Lopez, Iman Awan, Mar Bustamante, Claire L. Hill, Gabrielle Aisabonoko, Kathleen R. Chang, Sangbin Park, Franz Wendler, Seung K. Kim, Ethan Sung, Yulia Sudarikova, Sichen Liu
The existence of three independent binary systems for conditional gene expression (Gal4/UAS; LexA/LexAop; QF/QUAST) has greatly expanded versatile genetic analyses in the fruit fly Drosophila melanogaster; however, the experimental application of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e9f753c4abe8b67aa7b4829c7a548d7
https://doi.org/10.1101/2020.08.18.256461
https://doi.org/10.1101/2020.08.18.256461
Publikováno v:
Cell reports. 39(3)
Resistance to apoptosis due to caspase deregulation is considered one of the main hallmarks of cancer. However, the discovery of novel non-apoptotic caspase functions has revealed unknown intricacies about the interplay between these enzymes and tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f9635316b0e3a17fc4eaeef638c171
https://pubmed.ncbi.nlm.nih.gov/35443185
https://pubmed.ncbi.nlm.nih.gov/35443185
SummaryResistance to apoptosis due to caspase deregulation is considered one of the main hallmarks of cancer. However, the discovery of novel non-apoptotic caspase functions has revealed unknown intricacies about the interplay between these enzymes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4391794d25ef7ad9300eedd1243157e3
https://doi.org/10.1101/2020.07.27.223404
https://doi.org/10.1101/2020.07.27.223404
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
EMBO Reports
instname
EMBO Reports
Caspase malfunction in stem cells often precedes the appearance and progression of multiple types of cancer, including human colorectal cancer. However, the caspase‐dependent regulation of intestinal stem cell properties remains poorly understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5d275e1fcf4ff2964f4ad9ae0f00ca
http://hdl.handle.net/10261/223790
http://hdl.handle.net/10261/223790