Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Luis A. Fonseca-Fonseca"'
Autor:
María A. Bécquer-Viart, José González-Yaque, Luis A. Fonseca-Fonseca, Yanier Núñez-Figueredo, Gilberto L. Pardo Andreu
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 6, Iss 2, Pp 72-80 (2018)
Context: Some flavonoids have been described as neuroprotectors. Gossypitrin (Gos) is a natural occurring flavonoid and the main bioactive substance from the flowers of Talipariti elatum Sw. (Majagua azul), traditionally used in Cuba as expectorant a
Externí odkaz:
https://doaj.org/article/8406b58e62d040778535fc731dcc45b4
Autor:
Alejandro Saúl Padrón-Yaquis, Yasmine Nonose, Yaquelin Ortiz-Miranda, Yanier Nuñez-Figueredo, Yanay Montano-Peguero, Javier Jiménez-Martin, Adriano Martimbianco de Assis, Luis Arturo Fonseca-Fonseca, Gretchen Bergado, Gilberto L. Pardo-Andreu, Roberto Menéndez Soto del Valle, Maylin Wong-Guerra, Daniela Hernández-Enseñat, Jeney Ramírez-Sánchez, Diogo O. Souza, Tiago F. Outeiro, Abel Mondelo-Rodriguez, Tania Carmenate, Odalys Valdés
Publikováno v:
NeuroToxicology. 87:70-85
The number of people with dementia worldwide is estimated at 50 million by 2018 and continues to rise mainly due to increasing aging and population growth. Clinical impact of current interventions remains modest and all efforts aimed at the identific
Autor:
Fillipe M. de Araújo, Luis Arturo Fonseca-Fonseca, Victor Diogenes Amaral da Silva, Maylin Wong-Guerra, Yamila Verdecia-Reyes, Tiago F. Outeiro, Jeney Ramírez-Sánchez, Estael Ochoa-Rodríguez, Silvia Lima Costa, Yanier Nuñez-Figueredo, Rejane Conceição Santana, Padrón Yaquis Alejandro Saúl
Publikováno v:
NeuroToxicology. 82:89-98
We have previously shown that JM-20, a new chemical entity consisting of 1,5-benzodiazepine fused to a dihydropyridine moiety, protects against rotenone-induced neurotoxicity in an experimental model of Parkinson's disease (PD). The aim of this study
Autor:
Daniela Hernández-Enseñat, Yasmine Nonose, Yanier Nuñez-Figueredo, Odalys Valdés, Diogo O. Souza, Yanay Montano-Peguero, Tiago F. Outeiro, Javier Jiménez-Martin, Gilberto L. Pardo-Andreu, Alejandro Saúl Padrón-Yaquis, Roberto Menéndez Soto del Valle, Abel Mondelo-Rodriguez, Tania Carmenate, Jeney Ramírez-Sánchez, Yaquelin Ortiz-Miranda, Luis Arturo Fonseca-Fonseca, Gretchen Bergado, Adriano Martimbianco de Assis, Maylin Wong-Guerra
Alzheimer's disease (AD) is a neurodegenerative disease that worsens with aging. Today, there is a worldwide effort to find new drugs that could delay the onset, slow the progression, or improve symptoms of AD. Oral administration of aluminum to rode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cffd99584188162e5d72dc25329376c
https://doi.org/10.21203/rs.3.rs-163869/v1
https://doi.org/10.21203/rs.3.rs-163869/v1
Autor:
Luis Arturo Fonseca-Fonseca, René Delgado-Hernández, Estael Ochoa-Rodríguez, Elisa Nicoloso Simões-Pires, Jeney Ramírez-Sánchez, Yamila Verdecia-Reyes, Yanier Nuñez-Figueredo, Maylin Wong-Guerra, Gilberto L. Pardo-Andreu, Laura García-Pupo, Christianne Gazzana Salbego, Diogo O. Souza
Publikováno v:
European journal of pharmacology. 899
Cerebral ischemia constitutes the most frequent type of cerebrovascular disease. The reduction of blood supply to the brain initiates the ischemic cascade starting from ionic imbalance to subsequent glutamate excitotoxicity, neuroinflammation and oxi
Autor:
Wong Guerra Maylin, René Delgado Hernádez, Estael Ochoa-Rodríguez, Juan Segura-Aguilar, Luis Arturo Fonseca-Fonseca, Wagno Alcântara de Santana, Yamila Verdecia-Reyes, Silva Lima Costa, N.J. Menezes-Filho, Yanier Nuñez-Figueredo, Joana Oliveira, Jeney Ramírez Sánchez, Victor Diogenes Amaral da Silva, Teresa Cristina Silva Costa
Publikováno v:
Neurotoxicity Research. 36:279-291
The etiology of Parkinson’s disease is not completely understood and is believed to be multifactorial. Neuronal disorders associated to oxidative stress and mitochondrial dysfunction are widely considered major consequences. The aim of this study w
Autor:
Luis Arturo Fonseca-Fonseca, Roberto Menéndez Soto del Valle, Gilberto L. Pardo-Andreu, Diogo O. Souza, Yanier Nuñez-Figueredo, Javier Jiménez-Martin, Jeney Ramírez-Sánchez, Adriano Martimbianco de Assis, Maylin Wong-Guerra
Publikováno v:
Neurological Research. 39:649-659
Objective: Scopolamine (SCO) administration to rats induces molecular features of AD and other dementias, including impaired cognition, increased oxidative stress, and imbalanced cholinergic transmission. Although mitochondrial dysfunction is involve
Autor:
Luis Arturo Fonseca-Fonseca, Diogo O. Souza, Nelson Merino García, Odalys Valdés Martínez, Abel Mondelo-Rodriguez, Roberto Menéndez Soto del Valle, Guillermo Aparicio Lopez, Yanay Montano-Peguero, Jeney Ramírez-Sánchez, Javier Jiménez-Martin, Gilberto L. Pardo-Andreu, Alejandro Saúl Padrón-Yaquis, João Rocha, Adriano Martimbianco de Assis, Maylin Wong-Guerra, Fernanda D Avila, Yanier Nuñez-Figueredo
Publikováno v:
Neurological research. 41(5)
Objective: JM-20, a novel hybrid synthetic molecule, has been reported to have antioxidant, mitoprotective, anti-excitotoxic, anti-apoptotic and anti-inflammatory properties. However, the neuroprotective effect of JM-20 against memory impairment in p
Autor:
Silvia Lima Costa, Yanier Nuñez-Figueredo, Maylin Wong-Guerra, Padrón Yaquis Alejandro Saúl, Jeney Ramírez-Sánchez, Yanay Montano-Peguero, Victor Diogenes Amaral da Silva, Luis Arturo Fonseca-Fonseca, Gilberto L. Pardo-Andreu, Mondelo Rodriguez Abel
Publikováno v:
Neuroscience letters. 690
Oxidative stress and mitochondrial dysfunction are two pathophysiological factors often associated with the neurodegenerative process involved in Parkinson's disease (PD). The aim of this study was to investigate the effects of a novel hybrid molecul