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pro vyhledávání: '"Luis A. Casorla"'
Autor:
Avan Antia, David M. Alvarado, Qiru Zeng, Luis A. Casorla-Perez, Deanna L. Davis, Naomi M. Sonnek, Matthew A. Ciorba, Siyuan Ding
Publikováno v:
Viruses, Vol 16, Iss 4, p 634 (2024)
The Omicron variant of SARS-CoV-2, characterized by multiple subvariants including BA.1, XBB.1.5, EG.5, and JN.1, became the predominant strain in early 2022. Studies indicate that Omicron replicates less efficiently in lung tissue compared to the an
Externí odkaz:
https://doaj.org/article/38974c74f9894c49aa5e9ae3369a7b50
Autor:
Luis Alberto Casorla-Perez, Ranya Guennoun, Ciro Cubillas, Bo Peng, Kerry Kornfeld, David Wang
Publikováno v:
Journal of Virology. 96
Orsay virus is the only known natural virus pathogen of Caenorhabditis elegans , which shares many evolutionarily conserved pathways with humans. We leveraged the powerful genetic tractability of C. elegans to characterize a novel interaction between
Autor:
Gowri Kalugotla, Sanghyun Lee, Lawrence Schriefer, Luis Alberto Casorla Perez, Huiyan Huang, Qun Lu, Anthony Orvedahl, Gary Silverman, Stephen Pak, David Wang, Megan T Baldridge
Publikováno v:
The Journal of Immunology. 208:114.13-114.13
Mutations in the autophagy gene EPG5 are responsible for Vici syndrome, a multisystem human genetic disease with a combined immunodeficiency component. However, the mechanism(s) by which EPG5 regulates immune signaling are incompletely understood. Pr
Publikováno v:
Virus Research
Highlights • Rotaviruses require the TGN to LE transporter CI-M6PR for cell entry. • Sortilin-1 was identified as a cell factor involved in rotavirus replication. • Rotaviruses require cathepsins also to enter Caco-2 cells.
Cathepsins, end
Cathepsins, end
Publikováno v:
Journal of Virology. 92
Astroviruses, members of the family Astroviridae , represent an important cause of human gastroenteritis in the world. The cellular factors required for astrovirus replication have been poorly studied. In this work, we evaluated the relevance of the
Akademický článek
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Autor:
Qiru Zeng, Avan Antia, Luis Alberto Casorla-Perez, Maritza Puray-Chavez, Sebla B. Kutluay, Matthew A. Ciorba, Siyuan Ding
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, much effort has been dedicated to identifying effective antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A number of calpain inhibitors
Externí odkaz:
https://doaj.org/article/ea4945db2bf6456cb0f9f479f9a0b715