Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Luis A Solchaga"'
Publikováno v:
Journal of Tissue Engineering, Vol 3 (2012)
This article discusses nonclinical and clinical data regarding the safety of recombinant human platelet-derived growth factor-BB as a component of the Augment ® Bone Graft ( Augment ). Augment is a bone graft substitute intended to be used as an alt
Externí odkaz:
https://doaj.org/article/315185d48cc7450ea345226f434ac9e1
Publikováno v:
BioTechniques, Vol 42, Iss 6, Pp 732-737 (2007)
Aggregate culture provides a three-dimensional (3-D) environment for differentiating or differentiated cells; it is particularly useful to study in vitro chondrogenesis and cartilage biology. We have recently ported this method from a conical tube-ba
Externí odkaz:
https://doaj.org/article/631f51d3f55547e38e6e1a6a94a6b337
Publikováno v:
BioTechniques, Vol 39, Iss 5, Pp 687-691 (2005)
We have developed an improved method for preparing cell aggregates for in vitro chondrogenesis studies. This method is a modification of a previously developed conical tube-based culture system that replaces the original 15-mL polypropylene tubes wit
Externí odkaz:
https://doaj.org/article/db72c12d2d504a41a32fb4295e91af6a
Publikováno v:
Stem Cells International, Vol 2011 (2011)
Allogeneic hematopoietic stem cell transplantation is the main curative therapy for many hematologic malignancies. Its potential relies on graft-versus-tumor effects which associate with graft-versus-host disease. Mesenchymal stromal cells (MSCs) pos
Externí odkaz:
https://doaj.org/article/57e3bcb54c1d49308b8a45f5e985f9da
Autor:
Luane Reyes, Alice Lin, Ramzey Abujarour, Thomas H. Lee, Betsy Rezner, Bahram Valamehr, Luis A. Solchaga, Wen Bo Wang
Publikováno v:
Blood. 136:25-25
FT538 is an investigational, off-the-shelf, multiplexed engineered natural killer (NK) cell cancer immunotherapy that is derived from a clonal master induced pluripotent stem cell (iPSC) line engineered with three functional components to enhance inn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db4f95a8ce2bf0c746d95019ed31a77b
https://doi.org/10.1182/blood-2020-141922
https://doi.org/10.1182/blood-2020-141922
Autor:
Rodrigo A. Somoza, Arnold I. Caplan, Mark D. Schluchter, Seunghee Margevicius, Donald P. Lennon, Luis A. Solchaga
Publikováno v:
Tissue engineering. Part A. 24(23-24)
Tissue engineering requires large numbers of cells with enhanced differentiation properties. Thus, the effect of expansion conditions must be explored. Human and rat marrow-derived mesenchymal stem cells (hMSCs and rMSCs, respectively) were comparati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3415a35a34462256d047d103bf65c41e
https://pubmed.ncbi.nlm.nih.gov/29936884
https://pubmed.ncbi.nlm.nih.gov/29936884
Autor:
Jeffery J. Auletta, Sudipto Ganguly, Chen Liu, Kenneth R. Cooke, Zhenghong Lee, Megan Tyler, Fangjing Wang, Luis A. Solchaga, David L. Wilson, Leland Metheny, Rocio Guardia-Wolff, M. Keller, Theodore Bowen, Ines A. Silva, Saada Eid, Patiwet Wuttisarnwattana
Publikováno v:
Stem Cells. 33:601-614
We sought to define the effects and underlying mechanisms of human, marrow-derived mesenchymal stromal cells (hMSCs) on graft-versus-host disease (GvHD) and graft-versus-leukemia (GvL) activity. Irradiated B6D2F1 mice given C57BL/6 BM and splenic T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeb00da575d0c01bee78e3b0e5be5c93
https://doi.org/10.1002/stem.1867
https://doi.org/10.1002/stem.1867
Autor:
Christopher K. Hee, Luis A. Solchaga, Joshua S. Dines, Alison Bendele, Vivek Shah, Leo B. Snel, Hans K. Kestler
Publikováno v:
Journal of Orthopaedic Research. 32:145-150
This study compared the effect of intra-tendon (IT) delivery of recombinant human platelet-derived growth factor-BB (rhPDGF-BB), platelet-rich plasma (PRP) and corticosteroids in a rat tendinopathy model. Seven days after collagenase induction of ten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a54ff0f564a89d3d254f5b7f30b75ad
https://doi.org/10.1002/jor.22483
https://doi.org/10.1002/jor.22483
Publikováno v:
Current Pharmaceutical Design. 19:3384-3390
Recombinant human PDGF BB homodimer (rhPDGF-BB) is a potent recruiter of, and strong mitogenic factor for, cells crucial to musculoskeletal tissue repair, including mesenchymal stem cells (MSCs), osteogenic cells and tenocytes. rhPDGF-BB also upregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b97c45094f214425ac8e1e6e52611e
https://doi.org/10.2174/1381612811319190005
https://doi.org/10.2174/1381612811319190005
Publikováno v:
Stem Cells International, Vol 2013 (2013)
Stem Cells International
Stem Cells International
Bone-marrow-derived mesenchymal stem cells (MSCs) have the potential to differentiate into a number of phenotypes, including adipocytes. Adipogenic differentiation has traditionally been performed in monolayer culture, and, while the expression of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fc565a4a6b65484021fa8057c60fd4
https://doi.org/10.1155/2013/806525
https://doi.org/10.1155/2013/806525