Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Luis, Villanueva"'
Autor:
Primo N. Lara, Luis Villanueva, Carolina Ibanez, Mustafa Erman, Jae Lyun Lee, Daniel Heinrich, Oleg Nikolaevich Lipatov, Craig Gedye, Erhan Gokmen, Alejandro Acevedo, Andrey Semenov, Se Hoon Park, Rustem Airatovich Gafanov, Fatih Kose, Mark Jones, Xiaoqi Du, Mihaela Munteanu, Rodolfo Perini, Toni K. Choueiri, Robert J. Motzer
Publikováno v:
BMC Cancer, Vol 23, Iss S1, Pp 1-12 (2024)
Abstract Background Immunotherapy-based combinations have emerged as standard therapies for patients with metastatic renal cell carcinoma (mRCC). Pembrolizumab, a PD-1 inhibitor, combined with epacadostat, an indoleamine 2,3-deoxygenase 1 selective i
Externí odkaz:
https://doaj.org/article/f27c30f1bd8e406580492b76ee1bb216
Autor:
Anna Sayol-Altarriba, Andrea Aira, Anna Villasante, Rosa Albarracín, Joana Faneca, Gregori Casals, José Luis Villanueva-Cañas, Climent Casals-Pascual
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Short-chain fatty acids (SCFAs) represent a cornerstone of gut health, serving as critical mediators of immune modulation and overall host homeostasis. Patients with dysbiosis caused by Clostridioides difficile infection (CDI) typically exhibit lower
Externí odkaz:
https://doaj.org/article/bfc9c21d830441c59383fce7aceec455
Autor:
José Luis Villanueva-Cañas, Narcis Fernandez-Fuentes, Dominik Saul, Robyn Laura Kosinsky, Catherine Teyssier, Malgorzata Ewa Rogalska, Ferran Pegenaute Pérez, Baldomero Oliva, Cedric Notredame, Miguel Beato, Priyanka Sharma
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109584- (2024)
Summary: Peptidyl arginine deiminases (PADIs) catalyze protein citrullination, a post-translational conversion of arginine to citrulline. The most widely expressed member of this family, PADI2, regulates cellular processes that impact several disease
Externí odkaz:
https://doaj.org/article/dcca59766b1249ce963e9b46e07add27
Autor:
Rebecca Dikow, Corey DiPietro, Michael Trizna, Hanna BredenbeckCorp, Madeline Bursell, Jenna Ekwealor, Richard Hodel, Nilda Lopez, William Mattingly, Jeremy Munro, Richard Naples, Candace Oubre, Drew Robarge, Sara Snyder, Jennifer Spillane, Melinda Jane Tomerlin, Luis Villanueva, Alexander White
Publikováno v:
Research Ideas and Outcomes, Vol 9, Iss , Pp 1-17 (2023)
Applications of artificial intelligence (AI) and machine learning (ML) have become pervasive in our everyday lives. These applications range from the mundane (asking ChatGPT to write a thank you note) to high-end science (predicting future weather pa
Externí odkaz:
https://doaj.org/article/4c58a3fc4f594ec3a9e7409750eaa3fc
Autor:
Vincent Kofman, Geronimo Luis Villanueva, Thomas J. Fauchez, Avi M. Mandell, Ted M. Johnson, Allison Payne, Natasha Latouf, Soumil Kelkar
Publikováno v:
The Planetary Science Journal, Vol 5, Iss 9, p 197 (2024)
The atmospheres and surfaces of planets show a tremendous amount of spatial variation, which has a direct effect on the spectrum of the object, even if this may not be spatially resolved. Here, we apply hyperrealistic radiative simulations of Earth a
Externí odkaz:
https://doaj.org/article/9e49163c0ef848b9ad928516f150740c
Autor:
Marta Santos Bravo, Rodrigo Alonso, Dafne Soria, Sonsoles Sánchez Palomino, Ángela Sanzo Machuca, Cristina Rodríguez, José Alcamí, Francisco Díez-Fuertes, Àlvar Simarro Redon, Juan Carlos Hurtado, Francesc Fernández Avilés, Marta Bodro, Elisa Rubio, Jose Luis Villanueva, Andrea Vergara, Pedro Castro, Montserrat Tuset, Genoveva Cuesta, Pedro Puerta, Carolina García, María del Mar Mosquera Gutiérrez, Miguel J. Martínez, Jordi Vila, Alex Soriano, María Ángeles Marcos
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Remdesivir (RDV) was the first antiviral drug approved by the FDA to treat severe coronavirus disease-2019 (COVID-19) patients. RDV inhibits SARS-CoV-2 replication by stalling the non structural protein 12 (nsp12) subunit of the RNA-dependen
Externí odkaz:
https://doaj.org/article/5d64bf880a9e4427abb2ca9e84c9ba09
Autor:
Fernando Revoredo-Rego, Gustavo Reaño-Paredes, José de Vinatea-de Cárdenas, Fritz Kometter-Barrios, Luis Villanueva-Alegre, Guillermo Herrera-Chávez, José Arenas-Gamio
Publikováno v:
Cirugía y Cirujanos, Vol 90, Iss 3 (2022)
Objetivos: Comparar los resultados a corto plazo de pacientes intervenidos mediante pancreatectomía distal abierta (PDA) y laparoscópica (PDL); y analizar si el lugar de la sección del páncreas tiene relación con la formación de fístula pancre
Externí odkaz:
https://doaj.org/article/4394096264aa49a89fa658c12404718c
Autor:
William R. Blevins, Jorge Ruiz-Orera, Xavier Messeguer, Bernat Blasco-Moreno, José Luis Villanueva-Cañas, Lorena Espinar, Juana Díez, Lucas B. Carey, M. Mar Albà
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Genome-wide studies of de novo genes have tended to focus on genomic open reading frames (ORFs). Here, Blevins et al. use deep transcriptomics and synteny information to identify de novo transcripts in the yeast Saccharomyces cerevisiae, many of whic
Externí odkaz:
https://doaj.org/article/a21273671edd495a97f282be1951fb46
Publikováno v:
Tesis (Lima), Vol 13, Iss 16, Pp 43-63 (2020)
Este artículo analiza las tres tendencias de los estudiosos al tratar del personaje histórico Juan Santos Atahualpa: la versión franciscana, la versión académica (histórica, etnológica, periodística, etc.) y la versión oral (recogida por Enr
Externí odkaz:
https://doaj.org/article/38a0cf58f74d45938acb8ada101e6f20
Autor:
Alejandro La Greca, Nicolás Bellora, François Le Dily, Rodrigo Jara, Ana Silvina Nacht, Javier Quilez Oliete, José Luis Villanueva, Enrique Vidal, Gabriela Merino, Cristóbal Fresno, Inti Tarifa Reischle, Griselda Vallejo, Guillermo Vicent, Elmer Fernández, Miguel Beato, Patricia Saragüeta
Publikováno v:
eLife, Vol 11 (2022)
Estrogen (E2) and Progesterone (Pg), via their specific receptors (ERalpha and PR), are major determinants in the development and progression of endometrial carcinomas, However, their precise mechanism of action and the role of other transcription fa
Externí odkaz:
https://doaj.org/article/02b70d9b6d384a8291dce6a6fadfd073