Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Luis, Molto"'
Autor:
Charles Tannenbaum, James H. Finke, Brian Rini, Ronald Bukowski, Luis Molto, Kaushik Biswas, Patricia Rayman, Daisuke Kudo, Cynthia Hilston, Gaurisankar Sa, Tanya Das
The ability to induce T-cell apoptosis is one mechanism by which tumors evade the immune system, although the molecules involved remain controversial. We found that renal cell carcinoma (RCC)–induced T-cell apoptosis was inhibited by >50% when cocu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::333274c8e4feb14083253f17758db700
https://doi.org/10.1158/0008-5472.c.6497093
https://doi.org/10.1158/0008-5472.c.6497093
Autor:
Charles Tannenbaum, James H. Finke, Brian Rini, Ronald Bukowski, Luis Molto, Kaushik Biswas, Patricia Rayman, Daisuke Kudo, Cynthia Hilston, Gaurisankar Sa, Tanya Das
Supplementary Figure 1 from GM1 and Tumor Necrosis Factor-α, Overexpressed in Renal Cell Carcinoma, Synergize to Induce T-Cell Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761325f8b5cf4180311762998ef4bce2
https://doi.org/10.1158/0008-5472.22373480.v1
https://doi.org/10.1158/0008-5472.22373480.v1
Akademický článek
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Autor:
Charles S. Tannenbaum, James H. Finke, Gaurisankar Sa, Ronald M. Bukowski, Luis Molto, Cynthia Hilston, Patricia Rayman, Tanya Das, Brian I. Rini, Kaushik Biswas, Daisuke Kudo
Publikováno v:
Cancer Research. 68:2014-2023
The ability to induce T-cell apoptosis is one mechanism by which tumors evade the immune system, although the molecules involved remain controversial. We found that renal cell carcinoma (RCC)–induced T-cell apoptosis was inhibited by >50% when cocu
Autor:
James H. Finke, Tarek Mekhail, Cheryl Nemec, Gheath Alatrash, Charles S. Tannenbaum, Thomas Olencki, Paul Elson, Amy Richmond, Ronald M. Bukowski, Luis Molto, Thomas E. Hutson
Publikováno v:
Journal of Clinical Oncology. 22:2891-2900
PurposeInterleukin-12 (IL-12) and interferon alfa-2b (IFN-α-2b) are pleiotropic cytokines with activity in renal cell carcinoma (RCC) and malignant melanoma (MM) as single agents. Preclinical studies suggest concurrent administration may have synerg
Autor:
Luis Molto, Ronald M. Bukowski, Martha K. Cathcart, Daisuke Kudo, Charles S. Tannenbaum, Ithaar Derweesh, Mark Thornton, Patricia Rayman, Ewa Paszkiewicz-Kozik, Christopher S. Ng, James H. Finke, Claudine Horton
Publikováno v:
The Journal of Immunology. 172:3480-3490
T cells from cancer patients are often functionally impaired, which imposes a barrier to effective immunotherapy. Most pronounced are the alterations characterizing tumor-infiltrating T cells, which in renal cell carcinomas includes defective NF-κB
Autor:
Christina Moon, Luis Molto, Patricia Rayman, Thomas Olencki, Charles S. Tannenbaum, Cynthia Combs, Paul Elson, Ithaar Derweesh, James H. Finke, Ronald M. Bukowski
Publikováno v:
Cancer Immunotherapy at the Crossroads ISBN: 9781468498448
Despite the presence of antigens on tumors, studies suggest that that the antitumor immune response is attenuated. Well-recognized immune dysfunction in T cells of tumor-bearing hosts is most pronounced in tumor-infiltrating lymphocytes (TIL), and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793c49321372a4d39f4f0e32231f4f64
https://doi.org/10.1007/978-1-59259-743-7_7
https://doi.org/10.1007/978-1-59259-743-7_7
Autor:
Luis, Molto, Pat, Rayman, Ewa, Paszkiewicz-Kozik, Mark, Thornton, Lisa, Reese, John C, Thomas, Tanya, Das, Daisuke, Kudo, Ronald, Bukowski, James, Finke, Charles, Tannenbaum
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(11)
Tumors induce T-cell apoptosis as a mechanism of inhibiting antitumor immunity. Using coculture experiments, it has been shown that tumor lines stimulate T-cell apoptosis by a pathway involving a mitochondrial permeability transition and cytochrome c