Zobrazeno 1 - 10
of 996
pro vyhledávání: '"Luis, De Lecea"'
Publikováno v:
Brain Stimulation, Vol 16, Iss 6, Pp 1743-1752 (2023)
Transcranial ultrasound neuromodulation is a promising potential therapeutic tool for the noninvasive treatment of neuropsychiatric disorders. However, the expansive parameter space and difficulties in controlling for peripheral auditory effects make
Externí odkaz:
https://doaj.org/article/6f9bb79b11734e90a54f64fedb568f68
Autor:
Juan F Quintana, Matthew C Sinton, Praveena Chandrasegaran, Lalit Kumar Dubey, John Ogunsola, Moumen Al Samman, Michael Haley, Gail McConnell, Nono-Raymond Kuispond Swar, Dieudonné Mumba Ngoyi, David Bending, Luis de Lecea, Annette MacLeod, Neil A Mabbott
Publikováno v:
PLoS Biology, Vol 21, Iss 11, p e3002389 (2023)
The meningeal space is a critical brain structure providing immunosurveillance for the central nervous system (CNS), but the impact of infections on the meningeal immune landscape is far from being fully understood. The extracellular protozoan parasi
Externí odkaz:
https://doaj.org/article/253eccf81f604fb09b7c9c3cff71ce65
Autor:
Chinyere Agbaegbu Iweka, Erica Seigneur, Amira Latif Hernandez, Sur Herrera Paredes, Mica Cabrera, Eran Blacher, Connie Tsai Pasternak, Frank M. Longo, Luis de Lecea, Katrin I. Andreasson
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Aging is associated with loss of circadian immune responses and circadian gene transcription in peripheral macrophages. Microglia, the resident macrophages of the brain, also show diurnal rhythmicity in regulating local immune responses and
Externí odkaz:
https://doaj.org/article/4c1d1881d39f43bcacd644ecfab69692
Autor:
Susan M. Tyree, Kimberly J. Jennings, Oscar C. Gonzalez, Shi-bin Li, Janet R. Nicholson, Moritz von Heimendahl, Luis de Lecea
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Optogenetic or pharmacological modulation of hypocretin neurons impacts mouse impulsivity in a Go/No-Go task, suggesting that these neurons play a key role in integrating salient stimuli and guiding responses to various environmental cues.
Externí odkaz:
https://doaj.org/article/21d6fa20b6574adcb522247874f3ea09
Autor:
Suraj B. Teegala, Pallabi Sarkar, Dashiel M. Siegel, Zhenyu Sheng, Lihong Hao, Nicholas T. Bello, Luis De Lecea, Kevin D. Beck, Vanessa H. Routh
Publikováno v:
Molecular Metabolism, Vol 76, Iss , Pp 101788- (2023)
Objective: The present study tests the hypothesis that changes in the glucose sensitivity of lateral hypothalamus (LH) hypocretin/orexin glucose-inhibited (GI) neurons following weight loss leads to glutamate plasticity on ventral tegmental area (VTA
Externí odkaz:
https://doaj.org/article/3e3e5feead66492db315da933d2eb502
Autor:
Juan F. Quintana, Praveena Chandrasegaran, Matthew C. Sinton, Emma M. Briggs, Thomas D. Otto, Rhiannon Heslop, Calum Bentley-Abbot, Colin Loney, Luis de Lecea, Neil A. Mabbott, Annette MacLeod
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Detailed insight into how the brain responds to Trypanosoma brucei infection is lacking. Here, single cell and spatial transcriptomics are integrated to characterise this response, identifying a unique crosstalk between microglia and plasma cells.
Externí odkaz:
https://doaj.org/article/20ce49abd0174cbcba8717412cc4cc41
Autor:
Wen- Bian, Luis de Lecea
Publikováno v:
Bio-Protocol, Vol 13, Iss 4 (2023)
The functions of sleep remain largely unclear, and even less is known about its role in development. A general strategy to tackle these questions is to disrupt sleep and measure the outcomes. However, some existing sleep deprivation methods may not b
Externí odkaz:
https://doaj.org/article/0c092c25f5114bb09e724db862428394
Autor:
Ritchie E. Brown, Luis de Lecea
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/9f6180c22e2249d3972aef40e4321f7c
Autor:
Shi‐Bin Li, Luis de Lecea
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 6, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/e8d6f3b294304346b14d95a063464449
Autor:
Jeremy C. Borniger, Luis de Lecea
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Immune factors (e.g., cytokines, chemokines) can alter the activity of neuronal circuits to promote “sickness behavior,” a suite of adaptive actions that organisms exhibit in response to infection/injury in order to maximize their chances of reco
Externí odkaz:
https://doaj.org/article/d8ce8dd06af7469eb58dd4085eca0ac4