Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Luigino A. Giancotti"'
Autor:
Sara Ilari, Filomena Lauro, Luigino Antonio Giancotti, Valentina Malafoglia, Concetta Dagostino, Micaela Gliozzi, Antonia Condemi, Jessica Maiuolo, Francesca Oppedisano, Ernesto Palma, Carlo Tomino, Daniela Salvemini, Vincenzo Mollace, Carolina Muscoli
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 975 (2021)
Paclitaxel is a chemotherapeutic drug used for cancer treatment. Chemotherapy-induced peripheral neuropathy (CIPN) is a common major dose-limiting side effect of many chemotherapeutic agents, including paclitaxel. CIPN is accompanied by mechanical an
Externí odkaz:
https://doaj.org/article/a9c05762715243a18482705647dd9bfb
Autor:
Valentina Malafoglia, Monica Celi, Carolina Muscoli, Sara Ilari, Filomena Lauro, Luigino Antonio Giancotti, Chiara Morabito, Maurizio Feola, Umberto Tarantino, William Raffaeli
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background The incidence of post-surgical chronic pain ranges between 20% and 40% in Europe. Osteoarthritis pain after prosthesis implantation is one of the most severe secondary syndromes, depending not only on surgery but also on organic c
Externí odkaz:
https://doaj.org/article/d665edb685994255b07aa779c79739c1
Autor:
Kathryn Braden, Michela Campolo, Ying Li, Zhoumou Chen, Timothy M. Doyle, Luigino Antonio Giancotti, Emanuela Esposito, Jinsong Zhang, Salvatore Cuzzocrea, Christopher Kent Arnatt, Daniela Salvemini
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 383:172-181
Autor:
Sara Ilari, Concetta Dagostino, Valentina Malafoglia, Filomena Lauro, Luigino Antonio Giancotti, Antonella Spila, Stefania Proietti, Domenica Ventrice, Milena Rizzo, Micaela Gliozzi, Ernesto Palma, Fiorella Guadagni, Daniela Salvemini, Vincenzo Mollace, Carolina Muscoli
Publikováno v:
Antioxidants, Vol 9, Iss 12, p 1284 (2020)
In clinical practice, inflammatory pain is an important, unresolved health problem, despite the utilization of non-steroidal anti-inflammatory drugs (NSAIDs). In the last decade, different studies have proven that reactive oxygen species (ROS) and re
Externí odkaz:
https://doaj.org/article/b42f5487aaff4d0db40ad2b1d198e625
Autor:
Sara Ilari, Luigino Antonio Giancotti, Filomena Lauro, Micaela Gliozzi, Valentina Malafoglia, Ernesto Palma, Marco Tafani, Matteo Antonio Russo, Carlo Tomino, Massimo Fini, Daniela Salvemini, Vincenzo Mollace, Carolina Muscoli
Publikováno v:
Antioxidants, Vol 9, Iss 11, p 1103 (2020)
Neuropathic pain is a chronic painful disease. Data have shown that reactive oxygen species (ROS) are implicated in chronic pain. Particularly, the enhanced ROS production alters the mitochondrial genome and proteome through the accumulation of lipid
Externí odkaz:
https://doaj.org/article/ec5dcb20def546db8f9d5f78df5820be
Autor:
Fatma Mufti, Young‐Hwan Jung, Luigino A. Giancotti, Jinha Yu, Zhoumou Chen, Ngan B. Phung, Kenneth A. Jacobson, Daniela Salvemini
Publikováno v:
The FASEB Journal. 36
Autor:
Filomena Lauro, Luigino Antonio Giancotti, Sara Ilari, Concetta Dagostino, Micaela Gliozzi, Chiara Morabito, Valentina Malafoglia, William Raffaeli, Maurizio Muraca, Bianca M Goffredo, Vincenzo Mollace, Carolina Muscoli
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156039 (2016)
Citrus Bergamia Risso, commonly known as Bergamot, is a fruit whose Essential Oil and Bergamot Polyphenolic Fraction have numerous medicinal properties. It is also an excellent antioxidant and in this study, for the first time, its potential effect o
Externí odkaz:
https://doaj.org/article/5447157de5e140d5a52b68d17a2dc6e9
Autor:
Kenneth A. Jacobson, Fatma Mufti, Ngan B. Phung, Luigino Antonio Giancotti, Daniela Salvemini, Young-Hwan Jung, Jinha Yu, Zhoumou Chen
Publikováno v:
ACS Medicinal Chemistry Letters. 11:1281-1286
Eight P2Y14R antagonists, including three newly synthesized analogues, containing a naphthalene or phenyl-triazolyl scaffold were compared in a mouse model of chronic neuropathic pain (sciatic constriction). P2Y14R antagonists rapidly (≤30 min) rev
Autor:
Gina L. C. Yosten, Luigino Antonio Giancotti, Anthony H. Dickenson, Chun Guo, Willis K. Samson, Ryan Patel, Zhoumou Chen, Timothy M. Doyle, Caron M. Harada, Grant R. Kolar, Jinsong Zhang, Christopher J. Haddock, Daniela Salvemini
Publikováno v:
J Clin Invest
Treating neuropathic pain is challenging and novel non-opioid-based medicines are needed. Using unbiased receptomics, transcriptomic analyses, immunofluorescence, and in situ hybridization, we found that the expression of the orphan GPCR Gpr160 and G
Autor:
Francesca Bosco, Lorenza Guarnieri, Saverio Nucera, Miriam Scicchitano, Stefano Ruga, Antonio Cardamone, Samantha Maurotti, Cristina Russo, Anna Rita Coppoletta, Roberta Macrì, Irene Bava, Federica Scarano, Fabio Castagna, Maria Serra, Rosamaria Caminiti, Jessica Maiuolo, Sara Ilari, Filomena Lauro, Luigino Antonio Giancotti, Carolina Muscoli, Cristina Carresi, Ernesto Palma, Micaela Gliozzi, Vincenzo Musolino, Vincenzo Mollace
BackgroundSkeletal muscle atrophy is a condition characterized by a loss of muscle mass and muscle strength. This condition correlates with an imbalance between protein synthesis and protein degradation caused by the hyperactivation of some cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96690ab58e1eb18b22b5967fbe3b8076
https://doi.org/10.21203/rs.3.rs-1463017/v1
https://doi.org/10.21203/rs.3.rs-1463017/v1