Zobrazeno 1 - 10
of 459
pro vyhledávání: '"Luigina, Romani"'
Autor:
Enrico Garaci, Marilena Pariano, Emilia Nunzi, Claudio Costantini, Marina Maria Bellet, Cinzia Antognelli, Matteo Antonio Russo, Luigina Romani
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Moving from the earlier periods in which the lungs were believed to represent sterile environments, our knowledge on the lung microbiota has dramatically increased, from the first descriptions of the microbial communities inhabiting the healthy lungs
Externí odkaz:
https://doaj.org/article/d6a69ef18b7840a898bea0bdf7088e4a
Autor:
Matteo Antonio Russo, Matteo Puccetti, Claudio Costantini, Stefano Giovagnoli, Maurizio Ricci, Enrico Garaci, Luigina Romani
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Despite significant advances in diagnosis and treatment over recent decades, cardiovascular disease (CVD) remains one of the leading causes of morbidity and mortality in Western countries. This persistent burden is partly due to the incomplete unders
Externí odkaz:
https://doaj.org/article/54e01f45996f47ba901359843a96f167
Autor:
Teresa Zelante, Giuseppe Paolicelli, Francesca Fallarino, Marco Gargaro, Gianluca Vascelli, Marco De Zuani, Jan Fric, Petra Laznickova, Marcela Hortova Kohoutkova, Antonio Macchiarulo, Daniela Dolciami, Giuseppe Pieraccini, Lorenzo Gaetani, Giulia Scalisi, Caterina Trevisan, Barbara Frossi, Carlo Pucillo, Antonella De Luca, Emilia Nunzi, Roberta Spaccapelo, Marilena Pariano, Monica Borghi, Francesca Boscaro, Riccardo Romoli, Andrea Mancini, Lucia Gentili, Giorgia Renga, Claudio Costantini, Matteo Puccetti, Stefano Giovagnoli, Maurizio Ricci, Martina Antonini, Paolo Calabresi, Paolo Puccetti, Massimiliano Di Filippo, Luigina Romani
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Multiple sclerosis is a debilitating autoimmune disease, characterized by chronic inflammation of the central nervous system. While the significance of the gut microbiome on multiple sclerosis pathogenesis is established, the underlining mec
Externí odkaz:
https://doaj.org/article/ef3dd28764624aada7153b8839b12acc
Autor:
Enrico Garaci, Maurizio Paci, Claudia Matteucci, Claudio Costantini, Paolo Puccetti, Luigina Romani
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Phenotypic drug discovery (PDD) involves screening compounds for their effects on cells, tissues, or whole organisms without necessarily understanding the underlying molecular targets. PDD differs from target-based strategies as it does not require k
Externí odkaz:
https://doaj.org/article/ace5ad83713d4462b1a644ba82daee81
Autor:
Claudio Costantini, Marilena Pariano, Matteo Puccetti, Stefano Giovagnoli, Gioena Pampalone, Mirco Dindo, Barbara Cellini, Luigina Romani
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Humans interact with a multitude of microorganisms in various ecological relationships, ranging from commensalism to pathogenicity. The same applies to fungi, long recognized for their pathogenic roles in infection–such as in invasive fungal diseas
Externí odkaz:
https://doaj.org/article/ccc533b33dc54e209a747d0b6610b4ae
Autor:
Barbara Cellini, Gioena Pampalone, Emidio Camaioni, Marilena Pariano, Flavia Catalano, Teresa Zelante, Mirco Dindo, Lara Macchioni, Alessandra Di Veroli, Roberta Galarini, Fabiola Paoletti, Magdalena Davidescu, Claudia Stincardini, Gianluca Vascelli, Marina Maria Bellet, Julie Saba, Stefano Giovagnoli, Giorgio Giardina, Luigina Romani, Claudio Costantini
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Cystic fibrosis (CF) is an autosomal recessive disorder characterized by respiratory failure due to a vicious cycle of defective Cystic Fibrosis Transmembrane conductance Regulator (CFTR) function, chronic inflammation and recurrent bacteria
Externí odkaz:
https://doaj.org/article/ce0f5dab82524ec8a52f71d552b18f08
Autor:
Marilena Pariano, Anna Gidari, Claudia Stincardini, Sara Pierucci, Sabrina Bastianelli, Matteo Puccetti, Stefano Giovagnoli, Marina M. Bellet, Consuelo Fabi, Roberto Castronari, Cinzia Antognelli, Claudio Costantini, Maurizio Ricci, Daniela Francisci, Luigina Romani
Publikováno v:
Journal of Fungi, Vol 10, Iss 7, p 510 (2024)
Aspergillus fumigatus is an environmental fungus recently included in the fungal high-priority pathogens by the World Health Organization. While immunodeficiency and/or pre-existing lung damage represent a well-recognized fertile ground for fungal gr
Externí odkaz:
https://doaj.org/article/6ef681dd8dce4be88adf451ebb257c08
Autor:
Giorgia Renga, Fiorella D’Onofrio, Marilena Pariano, Roberta Galarini, Carolina Barola, Claudia Stincardini, Marina M. Bellet, Helmut Ellemunter, Cornelia Lass-Flörl, Claudio Costantini, Valerio Napolioni, Allison K. Ehrlich, Cinzia Antognelli, Massimo Fini, Enrico Garaci, Emilia Nunzi, Luigina Romani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract The aromatic amino acid L-tryptophan (Trp) is essentially metabolized along the host and microbial pathways. While much is known about the role played by downstream metabolites of each pathways in intestinal homeostasis, their role in lung i
Externí odkaz:
https://doaj.org/article/55ef849205bf4431a7d35facb0df52e6
Autor:
Giorgia Renga, Fiorella D’Onofrio, Marilena Pariano, Roberta Galarini, Carolina Barola, Claudia Stincardini, Marina M. Bellet, Helmut Ellemunter, Cornelia Lass-Flörl, Claudio Costantini, Valerio Napolioni, Allison K. Ehrlich, Cinzia Antognelli, Massimo Fini, Enrico Garaci, Emilia Nunzi, Luigina Romani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/e48746aa645243f7ad232bb4f71c290e
Autor:
Matteo Antonio Russo, Enrico Garaci, Andrea Frustaci, Massimo Fini, Claudio Costantini, Vasileios Oikonomou, Emilia Nunzi, Paolo Puccetti, Luigina Romani
Publikováno v:
Pharmacological Research, Vol 198, Iss , Pp 106994- (2023)
The functional interdependencies between the molecular components of a biological process demand for a network medicine platform that integrates systems biology and network science, to explore the interactions among biological components in health an
Externí odkaz:
https://doaj.org/article/51db04e8693545ccb04c7977575554ad