Esophageal pressure as estimation of pleural pressure: a study in a model of eviscerated chest

Autor: Gaetano Florio, Eleonora Carlesso, Francesco Mojoli, Fabiana Madotto, Luigi Vivona, Chiara Minaudo, Michele Battistin, Sebastiano Maria Colombo, Stefano Gatti, Simone Sosio, Antonio Pesenti, Giacomo Grasselli, Alberto Zanella

Publikováno v: BMC Anesthesiology, Vol 24, Iss 1, Pp 1-13 (2024)

Abstract Background Transpulmonary pressure is the effective pressure across the lung parenchyma and has been proposed as a guide for mechanical ventilation. The pleural pressure is challenging to directly measure in clinical setting and esophageal m

Externí odkaz: https://doaj.org/article/ff69d10334b9404fa789b2cad9405124

Successful Versus Failed Transition From Controlled Ventilation to Pressure Support Ventilation in COVID-19 Patients: A Retrospective Cohort Study

Autor: Melisa Polo Friz, MD, Emanuele Rezoagli, MD, Bijan Safaee Fakhr, MD, Gaetano Florio, MD, Eleonora Carlesso, MS, Riccardo Giudici, MD, Clarissa Forlini, MD, Francesca Tardini, MD, Thomas Langer, MD, Matteo Laratta, MD, Giampaolo Casella, MD, Andrea Forastieri Molinari, MD, Alessandro Protti, MD, Maurizio Cecconi, MD, Luca Cabrini, MD, Emanuela Biagioni, MD, Angela Berselli, MD, Lucia Mirabella, MD, Tommaso Tonetti, MD, Edoardo De Robertis, MD, Domenico Luca Grieco, MD, Massimo Antonelli, MD, Giuseppe Citerio, MD, Roberto Fumagalli, MD, Giuseppe Foti, MD, Alberto Zanella, MD, Giacomo Grasselli, MD, Giacomo Bellani, MD, for the COVID-19 Lombardy ICU Network, Amedeo Guzzardella, Luigi Vivona, Vittorio Scaravilli, Sebastiano Colombo, Alessio Cacioppola, Matteo Brioni, Clarissa Forlini, Francesca Tardini, Thomas Langer, Matteo Laratta, Giampaolo Casella, Maria Marsili, Serena Stropeni, Valentina Cordolcini, Francesco Crimella, Alessandro Santini, Massimiliano Greco, Michele Ferrari, Giacomo Iapichino, Paolo Severgnini, Davide Maraggia, Dario Gasberti, Alessandro Motta, Irene Coloretti, Stefano Busani, Martina Tosi, Ilenia Gatto, Carlo Montalto, Alberto Biondo, Ziad Algamain, Valentina Alaimo, Livio Tullo, Francesco Paolo Padovano, Giacinto Pizzilli, Irene Cavalli, Rachele Simonte, Davide Valeri, Gennaro DePascale, Simone Carelli, Valentina Noseda, Giacomo Cimicchi, Gaia Ottonello, Rossano Ghedin, Francesco Giacalone, Tiziana Bove, Francesco Meroi, Sara Scapol, Laura Pistidda, Angela Muretti, Savino Spadaro, Gaetano Scaramuzzo, Gioconda Ferraro, Giuseppe Gagliardi, Giovanni Sabbatini, Angelo Pezzi, Gabriele Sales, Giorgia Montrucchio, Andrea Carsetti, Federico Longhini, Maria Vargas, Plinio Calligaro, Ilaria Mariani, Vanessa Zambelli, Beatrice Noè, Filippo Serra

Publikováno v: Critical Care Explorations, Vol 6, Iss 2, p e1039 (2024)

OBJECTIVES:. In patients with COVID-19 respiratory failure, controlled mechanical ventilation (CMV) is often necessary during the acute phases of the disease. Weaning from CMV to pressure support ventilation (PSV) is a key objective when the patient�

Externí odkaz: https://doaj.org/article/4b6ae8e021cf455fba1cf96f2a53600a

Continuous external negative pressure improves oxygenation and respiratory mechanics in Experimental Lung Injury in Pigs – A pilot proof-of-concept trial

Autor: Martin Scharffenberg, Jakob Wittenstein, Moritz Herzog, Sebastian Tauer, Luigi Vivona, Raphael Theilen, Thomas Bluth, Thomas Kiss, Thea Koch, Giuseppe Fiorentino, Marcelo Gama de Abreu, Robert Huhle

Publikováno v: Intensive Care Medicine Experimental, Vol 8, Iss S1, Pp 1-22 (2020)

Abstract Background Continuous external negative pressure (CENP) during positive pressure ventilation can recruit dependent lung regions. We hypothesised that CENP applied regionally to the thorax or the abdomen only, increases the caudal end-expirat

Externí odkaz: https://doaj.org/article/7a602caaec39405baeaa748d24f0542e

Quantitative Metabolomics of Tissue, Perfusate, and Bile from Rat Livers Subjected to Normothermic Machine Perfusion

Autor: Caterina Lonati, Daniele Dondossola, Laimdota Zizmare, Michele Battistin, Leonie Wüst, Luigi Vivona, Margherita Carbonaro, Alberto Zanella, Stefano Gatti, Andrea Schlegel, Christoph Trautwein

Publikováno v: Biomedicines, Vol 10, Iss 3, p 538 (2022)

Machine perfusion (MP) allows the maintenance of liver cells in a metabolically active state ex vivo and can potentially revert metabolic perturbations caused by donor warm ischemia, procurement, and static cold storage (SCS). The present preclinical

Externí odkaz: https://doaj.org/article/bbb0c8a181f24b3497976bc716ee88b2

Sharing Mechanical Ventilator: In Vitro Evaluation of Circuit Cross-Flows and Patient Interactions

Autor: Sebastiano Maria Colombo, Michele Battistin, Eleonora Carlesso, Luigi Vivona, Fabio Carfagna, Carlo Valsecchi, Gaetano Florio, Luca Carenzo, Tommaso Tonetti, Vito Marco Ranieri, Maurizio Cecconi, Antonio Pesenti, Giacomo Grasselli, Alberto Zanella

Publikováno v: Membranes, Vol 11, Iss 7, p 547 (2021)

During the COVID-19 pandemic, a shortage of mechanical ventilators was reported and ventilator sharing between patients was proposed as an ultimate solution. Two lung simulators were ventilated by one anesthesia machine connected through two respirat

Externí odkaz: https://doaj.org/article/e253d7558f614398b5a9221984cb970c