Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Luigi Lania"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2031 (2023)
The guanine base in nucleic acids is, among the other bases, the most susceptible to being converted into 8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) when exposed to reactive oxygen species. In double-helix DNA, 8-oxodG can pair with adenine; hen
Externí odkaz:
https://doaj.org/article/749df458c0d842d5beddeb67eb55d584
Autor:
Giuliana Napolitano, Stefano Amente, Virginia Castiglia, Barbara Gargano, Vera Ruda, Xavier Darzacq, Olivier Bensaude, Barbara Majello, Luigi Lania
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/7eb0f2e066fc4b06a9edab63b7654dff
Autor:
Giuliana Napolitano, Stefano Amente, Virginia Castiglia, Barbara Gargano, Vera Ruda, Xavier Darzacq, Olivier Bensaude, Barbara Majello, Luigi Lania
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11245 (2010)
BackgroundThe mechanisms by which DNA damage triggers suppression of transcription of a large number of genes are poorly understood. DNA damage rapidly induces a release of the positive transcription elongation factor b (P-TEFb) from the large inacti
Externí odkaz:
https://doaj.org/article/e2e1c362746c4da2af35c2d2e3ad1ac1
Autor:
Giovanni Scala, Francesca Gorini, Susanna Ambrosio, Andrea M Chiariello, Mario Nicodemi, Luigi Lania, Barbara Majello, Stefano Amente
8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), a major product of the DNA oxidization process, has been proposed to have an epigenetic function in gene regulation and has been associated with genome instability. NGS-based methodologies are contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aabd12321287fa727d34c15d7213c08c
http://hdl.handle.net/11588/880167
http://hdl.handle.net/11588/880167
Autor:
Barbara Majello, Pier Giuseppe Pelicci, Giacomo Di Palo, Giovanni Scala, Sergio Cocozza, Stefano Amente, Francesca Gorini, Luigi Lania, Gaetano Ivan Dellino
Publikováno v:
Nucleic Acids Research
8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is the most common marker of oxidative stress and its accumulation within the genome has been associated with major human health issues such as cancer, aging, cardiovascular and neurodegenerative diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d93bd9f083bd7e2b788c876457c0ac
https://pubmed.ncbi.nlm.nih.gov/32198884
https://pubmed.ncbi.nlm.nih.gov/32198884
Autor:
Luigi Lania, Stefano Amente, Barbara Majello, Tiziana Castrignanò, Bin Ma, Gaetano Ivan Dellino, Sergio Cocozza, Piero Pucci, Giacomo Di Palo, Irina Stepanov, Giovanni Scala, Pier Giuseppe Pelicci, Francesca Gorini, Angela Moresano
Publikováno v:
Nucleic Acids Research
8-Oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is one of the major DNA modifications and a potent pre-mutagenic lesion prone to mispair with 2′-deoxyadenosine (dA). Several thousand residues of 8-oxodG are constitutively generated in the genome of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c54dbc36621224cd2b4f79ade735d18
https://doi.org/10.1093/nar/gky1152
https://doi.org/10.1093/nar/gky1152
Autor:
Deriggio Faicchia, Luigi Lania, Stefano Amente, Barbara Majello, Susanna Ambrosio, Giuseppe Matarese, Carmen D. Saccà, Francesca Gorini
Senescence is a stress-responsive cellular program that leads to cell cycle arrest . In cancer cells, senescence has profound implications for tumor aggressiveness and clinical outcome, but the molecular events that provoke cancer cells to undergo se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de90c515f0e4de4e2cc537e832ebbf3f
http://hdl.handle.net/11588/765152
http://hdl.handle.net/11588/765152
Autor:
Luigi Lania, Alice Passoni, Khulood W. Al-Sammarrae, Rafal S.A. Al-Anee, Ghassan M. Sulaiman, Renzo Bagnati, Giuliana Napolitano, Barbara Majello
Publikováno v:
Zeitschrift für Naturforschung C. 70:227-235
Hymenocrater longiflorus was collected from northern Iraq, and the chemical composition and antioxidant and cytotoxic activities of this plant were investigated. Ten compounds detected by HPLC-ESI/MS were identified as flavonoids and phenolic acids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2f371e3c04a3b572cd975b0d85f036
https://doi.org/10.1515/znc-2015-4145
https://doi.org/10.1515/znc-2015-4145
Autor:
Susanna Ambrosio, Stefano Amente, Barbara Majello, Raffaele A. Calogero, Mario Capasso, Luigi Lania, Carmen D. Saccà
Publikováno v:
Oncotarget
// Susanna Ambrosio 1 , Stefano Amente 2 , Carmen D. Sacca 1 , Mario Capasso 2,3 , Raffaele A. Calogero 4 , Luigi Lania 2 and Barbara Majello 1 1 Department of Biology, University of Naples ‘Federico II’, Naples, Italy 2 Department of Molecular M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c762593b93e39437b93f99ce87436a2d
http://hdl.handle.net/2318/1633566
http://hdl.handle.net/2318/1633566
Publikováno v:
Journal of Cellular Physiology. 229:538-544
Eukaryote's RNA polymerases II (RNAPII) have the feature to contain, at the carbossi-terminal region of their largest subunit Rpb1, a unique CTD domain. Rpb1-CTD is composed of an increasing number of repetitions of the Y1S2P3T4S5P6S7 heptad that goe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75d8f118f4a271c972d44a8366a9edfa
https://doi.org/10.1002/jcp.24483
https://doi.org/10.1002/jcp.24483