Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Luigi Gnudi"'
Autor:
Thamer Alobaid, Janaka Karalliedde, Matthew DL O’Connell, Luigi Gnudi, Katie Sheehan, Ka Keat Lim, Salma Ayis
Publikováno v:
Journal of Diabetes Research, Vol 2025 (2025)
Conclusion: Ethnicity and SES may be associated with differential risk of development and progression of DN and DR. The available evidence was limited by the number of studies and small samples for certain ethnic/socioeconomic groups.
Externí odkaz:
https://doaj.org/article/60f4b42ee8ae4a23b333ef3e81883414
Autor:
David Hopkins, Stephen Thomas, Salma Ayis, Janaka Karalliedde, Anastasios Mangelis, Nikolaos Fountoulakis, Julian Collins, Thamer S Alobaid, Luigi Gnudi, Prashanth Vas, Aicha Goubar
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Objectives We aim to evaluate estimated glomerular filtration rate (eGFR) patterns of progression in a multiethnic cohort of people with type I diabetes mellitus and with baseline eGFR ≥45 mL/min/1.73 m2.Design Observational cohort.Setting People w
Externí odkaz:
https://doaj.org/article/164f2c1bee744f909dbe988cbd2cdb5b
Autor:
Janaka Karalliedde, Nikos Fountoulakis, Dimitra Stathi, Antonella Corcillo, Maria Flaquer, Angeliki Panagiotou, Giuseppe Maltese, Anastasios Mangelis, Salma Ayis, Luigi Gnudi
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveThe mechanisms that explain the cardio-renal benefits of sodium glucose co-transporter 2 (SGLT-2) inhibitors are unknown. The effect of SGLT-2 inhibitors on arterial aging, measured by Aortic Pulse Wave Velocity (Ao-PWV) and Soluble Klotho (
Externí odkaz:
https://doaj.org/article/57fa6dfc782d47f8b177ef416831602b
Autor:
Jessica Kearney, Luigi Gnudi
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1343 (2023)
The diabetes epidemic and the increasing number of patients with diabetic chronic vascular complications poses a significant challenge to health care providers. Diabetic kidney disease is a serious diabetes-mediated chronic vascular complication and
Externí odkaz:
https://doaj.org/article/d07d8af7834b477c9fcbd3e8bce981f5
Autor:
Nikolaos Fountoulakis, Salma Ayis, Anastasios Mangelis, Angeliki Panagiotou, Maria Flaquer, Stanimir Stoilov, Giuseppe Maltese, GianCarlo Viberti, Stephen Thomas, Luigi Gnudi, Janaka Karalliedde
Publikováno v:
Artery Research, Vol 26, Iss Supplement 1 (2020)
Background and Aims: Active vitamin D [1,25(OH)2D3] deficiency is a potential modifiable risk factor for cardiovascular (CVD) and renal disease in patients with type 2 diabetes (T2DM) and stage 3/4 chronic kidney disease (CKD). Exact mechanisms are u
Externí odkaz:
https://doaj.org/article/c2ac1b54389142b5affe9030951fb919
Publikováno v:
BMC Medicine, Vol 17, Iss 1, Pp 1-3 (2019)
Abstract Background We have previously demonstrated in the DIABRISK-SL trial that a trimonthly pragmatic lifestyle modification (P-LSM), as compared to a 12-monthly LSM advice (C-LSM), significantly reduced the primary composite endpoint of predictor
Externí odkaz:
https://doaj.org/article/715be5e67756420ab0a22d15c0e793bf
Autor:
Mahen Wijesuriya, Nikolaos Fountoulakis, Nicola Guess, Sarath Banneheka, Laksha Vasantharajah, Martin Gulliford, Giancarlo Viberti, Luigi Gnudi, Janaka Karalliedde
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background There is an increasing incidence of type 2 diabetes mellitus (T2DM) in young urban South-Asians. We tested the effect of a pragmatic trimonthly lifestyle modification (LSM) programme (P-LSM) versus a less-intensive 12-monthly cont
Externí odkaz:
https://doaj.org/article/4da51d92aa5e41139f9f44522c7b47d8
Publikováno v:
Artery Research, Vol 24 (2018)
Background: Aortic Pulse Wave Velocity (Ao-PWV) predicts cardiovascular disease and renal dysfunction in Type 2 Diabetes (T2DM). Klotho is a circulating anti-ageing hormone that has direct cardio-renal protective effects in animal studies. We have pr
Externí odkaz:
https://doaj.org/article/b5bbb1e1722c4d89aaaca42f28d5c45f
Autor:
Anna Czajka, Saima Ajaz, Luigi Gnudi, Chandani Kiran Parsade, Peter Jones, Fiona Reid, Afshan N. Malik
Publikováno v:
EBioMedicine, Vol 2, Iss 6, Pp 499-512 (2015)
The purpose of this study was to determine if mitochondrial dysfunction plays a role in diabetic nephropathy (DN), a kidney disease which affects >100 million people worldwide and is a leading cause of renal failure despite therapy. A cross-sectional
Externí odkaz:
https://doaj.org/article/514890d9859e4b8cbf72f2b92f8f9a22
Autor:
Nikolaos Fountoulakis, Chiraag Thakrar, Kishan Patel, Giancarlo Viberti, Luigi Gnudi, Janaka Karalliedde
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 4 (2017)
BackgroundThe objective of this study was to evaluate whether aortic pulse wave velocity (Ao‐PWV) predicts estimated glomerular filtration rate (eGFR) decline in patients with type 2 diabetes mellitus. Methods and ResultsThis prospective single‐c
Externí odkaz:
https://doaj.org/article/1f668e19a07441fe9f380ddee1251e74