Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Luigi Fiaschi"'
Autor:
Marco Becherelli, Prachi Prachi, Elisa Viciani, Massimiliano Biagini, Luigi Fiaschi, Emiliano Chiarot, Sarah Nosari, Cecilia Brettoni, Sara Marchi, Marco Biancucci, Maria Rita Fontana, Francesca Montagnani, Fabio Bagnoli, Michèle A Barocchi, Andrea G O Manetti
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74718 (2013)
Staphylococcus aureus is an opportunistic pathogen, commensal of the human skin and nares, but also responsible for invasive nosocomial as well as community acquired infections. Staphylococcus aureus adheres to the host tissues by means of surface ad
Externí odkaz:
https://doaj.org/article/f5829010c3c34dde969e68d4f7c2ec6a
Autor:
Fabiana Falugi, Maria Scarselli, Fabio Bagnoli, Bruno Galletti, Letizia Arcidiacono, Antonina Torre, Clarissa Pozzi, Vincenzo Nardi-Dei, Maria Rita Fontana, Juliane Bubeck Wardenburg, Luigi Fiaschi, Guido Grandi, Kelly Tomaszewski, Rino Rappuoli, Benedetta Di Palo, Ravi Prakash Mishra, Michele Pallaoro, Elena Mori, Marco Soriani, Ilaria Ferlenghi
Publikováno v:
Clinical and Vaccine Immunology : CVI
Staphylococcus aureus alpha-hemolysin (Hla) assembles into heptameric pores on the host cell membrane, causing lysis, apoptosis, and junction disruption. Herein, we present the design of a newly engineered S. aureus alpha-toxin, HlaPSGS, which lacks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6f9d962a035a48555995b9fb479180
http://europepmc.org/articles/PMC4895005
http://europepmc.org/articles/PMC4895005
Autor:
Erwin Swennen, Rino Rappuoli, Barbara Baudner, Antonina Torre, Roberto Petracca, Luigi Fiaschi, Juliane Bubeck Wardenburg, Naoko Inoshima, Elisabetta Monaci, Sabrina Liberatori, C. Daniela Rinaudo, Cecilia Brettoni, Maria Rita Fontana, Silvia Maccari, Paolo Mariotti, Nicholas Valiante, Silvana Savino, Sarah Nosari, Elena Mori, Vincenzo Nardi-Dei, Bruno Galletti, Elena Cartocci, Marta Bacconi, Ennio De Gregorio, Guido Grandi, Giuseppe Lofano, Ravi Prakash Mishra, Derek T. O'Hagan, Sylvie Bertholet, Nathalie Norais, Olaf Schneewind, Michele Pallaoro, Sara Marchi, Elisabetta Soldaini, Maria Scarselli, Fabio Bagnoli, Silvia Rossi-Paccani, Giuliano Bensi, Paolo Ruggiero, Maria Grazia De Falco
Publikováno v:
Proceedings of the National Academy of Sciences. 112:3680-3685
Both active and passive immunization strategies against Staphylococcus aureus have thus far failed to show efficacy in humans. With the attempt to develop an effective S. aureus vaccine, we selected five conserved antigens known to have different rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14195a9e335b41675321eb3ba865b770
https://doi.org/10.1073/pnas.1424924112
https://doi.org/10.1073/pnas.1424924112
Autor:
Paolo Mariotti, Fabiana Falugi, Sarah Nosari, Guido Grandi, Maria Rita Fontana, Sabrina Liberatori, Alfredo Pezzicoli, Ravi Prakash Mishra, Luigi Fiaschi, Emrah Altindis, Maria Grazia De Falco, Fabio Bagnoli, Silvia Maccari, Davide Serruto
Publikováno v:
The Journal of Infectious Diseases. 206:1041-1049
Iron availability plays an essential role in staphylococcal pathogenesis. We selected FhuD2, a lipoprotein involved in iron-hydroxamate uptake, as a novel vaccine candidate against Staphylococcus aureus. Unprecedented for staphylococcal lipoproteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999f13d7b29a5889c111b62a865119ee
https://doi.org/10.1093/infdis/jis463
https://doi.org/10.1093/infdis/jis463
Autor:
Fabio Bagnoli, Ravi Prakash Mishra, Barbara Baudner, Luigi Fiaschi, Vincenzo Nardi-Dei, Rino Rappuoli, Erika Bartolini, Phil Boucher, Paolo Mariotti
Publikováno v:
OMICS: A Journal of Integrative Biology. 15:545-566
Vaccine research and development are experiencing a renaissance of interest from the global scientific community. There are four major reasons for this: (1) the lack of efficacious treatment for many devastating infections; (2) the emergence of multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4465d97f799fd028ffae276c3c5e2fe
https://doi.org/10.1089/omi.2010.0127
https://doi.org/10.1089/omi.2010.0127
Autor:
Rino Rappuoli, Luigi Fiaschi, Ernesto Oviedo-Orta, Erwin Swennen, Janice Spencer, June Irvine, Mariagrazia Pizza, Werner Pansegrau, Denise Candlish, Lorenza Tulli, Marco Soriani, Daniele Veggi, Maria Scarselli, Enrico Luzzi, Monica Giraldi, Rosanna Leuzzi, Barbara Baudner, Osman S. Cakici, Silvana Savino, Manuele Martinelli, Nunzia D’Urzo, Sara Marchi, Cecilia Brettoni, Domenico Maione, Anthony M. Buckley, Gillian Douce
Clostridium difficile is a spore-forming bacterium that can reside in animals and humans. C. difficile infection causes a variety of clinical symptoms, ranging from diarrhea to fulminant colitis. Disease is mediated by TcdA and TcdB, two large entero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f151c4f9ffa0fc83868162a4bb114ce7
https://europepmc.org/articles/PMC3719595/
https://europepmc.org/articles/PMC3719595/
Autor:
Vittorio Tedde, Manuele Biazzo, Luigi Fiaschi, Maria Scarselli, Patrizia Spigaglia, Paola Mastrantonio, Rossella Cioncada, Cesira Galeotti, Michèle A. Barocchi, Mariagrazia Pizza
Publikováno v:
Journal of medical microbiology. 62(Pt 9)
An increased incidence of Clostridium difficile infection (CDI) is associated with the emergence of epidemic strains characterized by high genetic diversity. Among the factors that may have a role in CDI is a family of 29 paralogues, the cell-wall pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6871b09865f2c87c4e8b6847066ac586
https://pubmed.ncbi.nlm.nih.gov/23722432
https://pubmed.ncbi.nlm.nih.gov/23722432
Autor:
Mariagrazia Pizza, Silvana Savino, Emmanuelle Palumbo, Sara Marchi, Brunella Brunelli, Luigi Fiaschi
Publikováno v:
Methods in Molecular Biology ISBN: 9781617793455
Most of the vaccines available today, albeit very effective, have been developed using traditional "old-style" methodologies. Technologies developed in recent years have opened up new perspectives in the field of vaccinology and novel strategies are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeb12aede80b59af9b7aeaa44767a5ab
https://doi.org/10.1007/978-1-61779-346-2_21
https://doi.org/10.1007/978-1-61779-346-2_21