Zobrazeno 1 - 10
of 453
pro vyhledávání: '"Luigi F. Agnati"'
Autor:
Diego Guidolin, Cinzia Tortorella, Manuela Marcoli, Chiara Cervetto, Raffaele De Caro, Guido Maura, Luigi F. Agnati
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 4, Iss 5, Pp 366-391 (2024)
Excitotoxicity represents a neuropathological process, describing the toxic actions of excitatory neurotransmitters, where the excessive or prolonged activation of glutamate receptors triggers a cascade of events leading to neuronal injury or death.
Externí odkaz:
https://doaj.org/article/d11ddcd2d1294f15a0039bd826ec03ae
Autor:
Diego Guidolin, Cinzia Tortorella, Manuela Marcoli, Chiara Cervetto, Raffaele De Caro, Guido Maura, Luigi F. Agnati
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1427 (2023)
Dopamine neurotransmission plays critical roles in regulating complex cognitive and behavioral processes including reward, motivation, reinforcement learning, and movement. Dopamine receptors are classified into five subtypes, widely distributed acro
Externí odkaz:
https://doaj.org/article/59a9cbd7c6b846c59f5dffde714816fe
Autor:
Manuela Marcoli, Luigi F. Agnati, Rafael Franco, Pietro Cortelli, Deanna Anderlini, Diego Guidolin, Chiara Cervetto, Guido Maura
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
A critical aspect of drug development in the therapy of neuropsychiatric diseases is the “Target Problem”, that is, the selection of a proper target after not simply the etiopathological classification but rather the detection of the supposed str
Externí odkaz:
https://doaj.org/article/5ef263a6d2994fb59888e462b984de7b
Publikováno v:
Life, Vol 13, Iss 4, p 940 (2023)
We present a brief historical and epistemological outline of investigations on the brain’s structure and functions. These investigations have mainly been based on the intermingling of chemical anatomy, new techniques in the field of microscopy and
Externí odkaz:
https://doaj.org/article/a4e0a8e7f3de49078c7e259e01a8a6a2
Autor:
Sarah Amato, Monica Averna, Diego Guidolin, Cristina Ceccoli, Elena Gatta, Simona Candiani, Marco Pedrazzi, Michela Capraro, Guido Maura, Luigi F. Agnati, Chiara Cervetto, Manuela Marcoli
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4677 (2023)
The ability of oxytocin (OT) to interact with the dopaminergic system through facilitatory D2-OT receptor (OTR) receptor-receptor interaction in the limbic system is increasingly considered to play roles in social or emotional behavior, and suggested
Externí odkaz:
https://doaj.org/article/c856f56a32d84108a1d88482ea6fa32e
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5805 (2022)
In the last decades, new evidence on brain structure and function has been acquired by morphological investigations based on synergic interactions between biochemical anatomy approaches, new techniques in microscopy and brain imaging, and quantitativ
Externí odkaz:
https://doaj.org/article/9771f0781801465d9d3907c92a175bf4
Autor:
Sarah Amato, Monica Averna, Diego Guidolin, Marco Pedrazzi, Simone Pelassa, Michela Capraro, Mario Passalacqua, Matteo Bozzo, Elena Gatta, Deanna Anderlini, Guido Maura, Luigi F. Agnati, Chiara Cervetto, Manuela Marcoli
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2326 (2022)
Background: Roles of astrocytes in the modulatory effects of oxytocin (OT) in central nervous system are increasingly considered. Nevertheless, OT effects on gliotransmitter release have been neglected. Methods: In purified astrocyte processes from a
Externí odkaz:
https://doaj.org/article/d2b13e2b1c2248a484c0386a4329f5ec
Autor:
Arianna Venturini, Mario Passalacqua, Simone Pelassa, Fabio Pastorino, Mariateresa Tedesco, Katia Cortese, Maria Cristina Gagliani, Giuseppina Leo, Guido Maura, Diego Guidolin, Luigi F. Agnati, Manuela Marcoli, Chiara Cervetto
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
It is widely recognized that extracellular vesicles subserve non-classical signal transmission in the central nervous system. Here we assess if the astrocyte processes, that are recognized to play crucial roles in intercellular communication at the s
Externí odkaz:
https://doaj.org/article/11d0f72c97cd4210b2d271787940efce
Autor:
Diego Guidolin, Cinzia Tortorella, Manuela Marcoli, Chiara Cervetto, Guido Maura, Luigi F. Agnati
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8656 (2021)
The discovery that receptors from all families can establish allosteric receptor–receptor interactions and variably associate to form receptor complexes operating as integrative input units endowed with a high functional and structural plasticity h
Externí odkaz:
https://doaj.org/article/c941107e40714df5b2fa0b6a2d55063d
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
The discovery of receptor-receptor interactions (RRI) has expanded our understanding of the role that G protein-coupled receptors (GPCRs) play in intercellular communication. The finding that GPCRs can operate as receptor complexes, and not only as m
Externí odkaz:
https://doaj.org/article/42788aa969ef4c54b8051c69a2a8eb0d