Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Luigi E. Xodo"'
Autor:
Eros Di Giorgio, Himanshi Choudhary, Annalisa Ferino, Ylenia Cortolezzis, Emiliano Dalla, Francesca D’Este, Marina Comelli, Valentina Rapozzi, Luigi E. Xodo
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108566- (2023)
Summary: In pancreatic ductal adenocarcinomas (PDAC), the KRASG12D-NRF2 axis controls cellular functions such as redox homeostasis and metabolism. Disruption of this axis through suppression of NRF2 leads to profound reprogramming of metabolism. Unbi
Externí odkaz:
https://doaj.org/article/155673efb0a645f6bd1db83427ce85ed
Autor:
Annalisa Ferino, Julien Marquevielle, Himanshi Choudhary, Giorgio Cinque, Coralie Robert, Anne Bourdoncle, Raffaella Picco, Jean-Louis Mergny, Gilmar F. Salgado, Luigi E. Xodo
Publikováno v:
ACS Omega, Vol 6, Iss 49, Pp 34092-34106 (2021)
Externí odkaz:
https://doaj.org/article/6d6584fbad484cc3a33b03455540ba6a
Autor:
Eros Di Giorgio, Luigi E. Xodo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Bi-directional transcription of Human Endogenous Retroviruses (hERVs) is a common feature of autoimmunity, neurodegeneration and cancer. Higher rates of cancer incidence, neurodegeneration and autoimmunity but a lower prevalence of autoimmune disease
Externí odkaz:
https://doaj.org/article/0f07a091cbc94048aa4ed3de2bd455cc
Autor:
Gilmar F. Salgado, Jean-Louis Mergny, Giorgio Cinque, Coralie Robert, Luigi E. Xodo, Annalisa Ferino, Raffaella Picco, Julien Marquevielle, Anne Bourdoncle, Himanshi Choudhary
Publikováno v:
ACS Omega
ACS Omega, ACS Publications, 2021, 6 (49), pp.34092-34106. ⟨10.1021/acsomega.1c05538⟩
ACS Omega, Vol 6, Iss 49, Pp 34092-34106 (2021)
ACS Omega, ACS Publications, 2021, 6 (49), pp.34092-34106. ⟨10.1021/acsomega.1c05538⟩
ACS Omega, Vol 6, Iss 49, Pp 34092-34106 (2021)
Recent studies have proven that the genetic landscape of pancreatic cancer is dominated by the KRAS oncogene. Its transcription is controlled by a G-rich motif (called 32R) located immediately upstream of the TSS. 32R may fold into a G-quadruplex (G4
Autor:
Himanshi Choudhary, Luigi E. Xodo
Publikováno v:
Handbook of Chemical Biology of Nucleic Acids ISBN: 9789811613135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca2d05d339e736e8863636841e6b9db0
https://doi.org/10.1007/978-981-16-1313-5_69-1
https://doi.org/10.1007/978-981-16-1313-5_69-1
Autor:
Eros Di Giorgio, Annalisa Ferino, Himanshi Choudhary, Phillip M.G. Löffler, Francesca D'Este, Valentina Rapozzi, Alexander Tikhomirov, Andrey Shchekotikhin, Stefan Vogel, Luigi E. Xodo
Publikováno v:
Di Giorgio, E, Ferino, A, Choudhary, H, Löffler, P M G, D'Este, F, Rapozzi, V, Tikhomirov, A, Shchekotikhin, A, Vogel, S & Xodo, L E 2022, ' Photosensitization of pancreatic cancer cells by cationic alkyl-porphyrins in free form or engrafted into POPC liposomes : The relationship between delivery mode and mechanism of cell death ', Journal of Photochemistry and Photobiology B: Biology, vol. 231, 112449 . https://doi.org/10.1016/j.jphotobiol.2022.112449
Cationic porphyrins bearing an alkyl side chain of 14 (2b) or 18 (2d) carbons dramatically inhibit proliferation of pancreatic cancer cells following treatment with light. We have compared two different ways of delivering porphyrin 2d: either in free
Autor:
Beatrice Tosoni, Rosalba Perrone, Sara N. Richter, Louis Flamand, Irene Zanin, Annalisa Ferino, Emanuela Ruggiero, Luigi E. Xodo, Sara Artusi, Matteo Nadai
Publikováno v:
Viruses
Volume 13
Issue 2
Viruses, Vol 13, Iss 196, p 196 (2021)
Volume 13
Issue 2
Viruses, Vol 13, Iss 196, p 196 (2021)
The herpes simplex virus 1 (HSV-1) genome is extremely rich in guanine tracts that fold into G-quadruplexes (G4s), nucleic acid secondary structures implicated in key biological functions. Viral G4s were visualized in HSV-1 infected cells, with massi
Autor:
Luigi E. Xodo, Annalisa Ferino
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1137, p 1137 (2021)
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1137, p 1137 (2021)
The promoter of the Kirsten ras (KRAS) proto-oncogene contains, upstream of the transcription start site, a quadruplex-forming motif called 32R with regulatory functions. As guanine under oxidative stress can be oxidized to 8-oxoguanine (8OG), we inv
Autor:
Annalisa, Ferino, Luigi E, Xodo
Publikováno v:
International Journal of Molecular Sciences
The promoter of the Kirsten ras (KRAS) proto-oncogene contains, upstream of the transcription start site, a quadruplex-forming motif called 32R with regulatory functions. As guanine under oxidative stress can be oxidized to 8-oxoguanine (8OG), we inv