Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Luigi Dolcetti"'
Autor:
Jinhai Deng, Teng Pan, Dan Wang, Yourae Hong, Zaoqu Liu, Xingang Zhou, Zhengwen An, Lifeng Li, Giovanna Alfano, Gang Li, Luigi Dolcetti, Rachel Evans, Jose M Vicencio, Petra Vlckova, Yue Chen, James Monypenny, Camila Araujo De Carvalho Gomes, Gregory Weitsman, Kenrick Ng, Caitlin McCarthy, Xiaoping Yang, Zedong Hu, Joanna C Porter, Christopher J Tape, Mingzhu Yin, Fengxiang Wei, Manuel Rodriguez-Justo, Jin Zhang, Sabine Tejpar, Richard Beatson, Tony Ng
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2080-2108 (2024)
Abstract Chemotherapy, the standard of care treatment for cancer patients with advanced disease, has been increasingly recognized to activate host immune responses to produce durable outcomes. Here, in colorectal adenocarcinoma (CRC) we identify oxal
Externí odkaz:
https://doaj.org/article/5559931ff7c94961b54686129b587544
Autor:
Sandhya Moise, Luigi Dolcetti, Francesco Dazzi, Paul Roach, Lee Buttery, Sheila MacNeil, Nick Medcalf
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 50, Iss 1, Pp 168-176 (2022)
Mesenchymal stromal cells (MSCs) show immunosuppressive effects both via cell-to-cell contact (direct) with immune cells and by producing paracrine factors and extracellular vesicles (indirect). A key challenge in delivering this therapeutic effect i
Externí odkaz:
https://doaj.org/article/553c2c08f92940b3af31d4ab98942208
Autor:
Chiara Mancino, Anna Pasto, Enrica De Rosa, Luigi Dolcetti, Marco Rasponi, Patrick McCulloch, Francesca Taraballi
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16640- (2023)
Post-traumatic osteoarthritis (PTOA) is one of the leading causes of disability in developed countries and accounts for 12% of all osteoarthritis cases in the United States. After trauma, inflammatory cells (macrophages amongst others) are quickly re
Externí odkaz:
https://doaj.org/article/5a89910dfdcc4f19aaebba8afb4bc9a6
Autor:
Paul R Barber, Rami Mustapha, Fabian Flores-Borja, Giovanna Alfano, Kenrick Ng, Gregory Weitsman, Luigi Dolcetti, Ali Abdulnabi Suwaidan, Felix Wong, Jose M Vicencio, Myria Galazi, James W Opzoomer, James N Arnold, Selvam Thavaraj, Shahram Kordasti, Jana Doyle, Jon Greenberg, Magnus T Dillon, Kevin J Harrington, Martin Forster, Anthony CC Coolen, Tony Ng
Publikováno v:
eLife, Vol 11 (2022)
Background: Advanced head and neck squamous cell carcinoma (HNSCC) is associated with a poor prognosis, and biomarkers that predict response to treatment are highly desirable. The primary aim was to predict progression-free survival (PFS) with a mult
Externí odkaz:
https://doaj.org/article/f01407f956a24b9e8f9a0385ed5d4e28
Autor:
Cristina Trento, Ilaria Marigo, Alice Pievani, Antonio Galleu, Luigi Dolcetti, Chun-Yin Wang, Marta Serafini, Vincenzo Bronte, Francesco Dazzi
Publikováno v:
Haematologica, Vol 102, Iss 5 (2017)
Bone marrow microenvironment is fundamental for hematopoietic homeostasis. Numerous efforts have been made to reproduce or manipulate its activity to facilitate engraftment after hematopoietic stem cell transplantation but clinical results remain unc
Externí odkaz:
https://doaj.org/article/18b8861518934911a42f735dbe6ea6c9
Autor:
Kenrick Ng, Giovanna Alfano, Fabian Flores-Borja, Rami Mustapha, Paul R Barber, Gregory Weitsman, Luigi Dolcetti, Ali Abdulnabi Suwaidan, Felix Wong, Jose M Vicencio, Myria Galazi, James W Opzoomer, James N Arnold, Selvam Thavaraj, Shahram Kordasti, Jana Doyle, Jon Greenberg, Magnus T Dillon, Kevin J Harrington, Martin Forster, Anthony CC Coolen, Tony Ng
Publikováno v:
Elife, 11, 1-22
Elife, 11, pp. 1-22
Elife, 11, pp. 1-22
Background:Advanced head and neck squamous cell carcinoma (HNSCC) is associated with a poor prognosis, and biomarkers that predict response to treatment are highly desirable. The primary aim was to predict progression-free survival (PFS) with a multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bede1585ff70f762d4065a1105f4dad
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/288117
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/288117
Autor:
Kenrick Ng, Giovanna Alfano, Fabian Flores-Borja, Rami Mustapha, Paul R Barber, Gregory Weitsman, Luigi Dolcetti, Ali Abdulnabi Suwaidan, Felix Wong, Jose M Vicencio, Myria Galazi, James W Opzoomer, James N Arnold, Selvam Thavaraj, Shahram Kordasti, Jana Doyle, Jon Greenberg, Magnus T Dillon, Kevin J Harrington, Martin Forster, Anthony CC Coolen, Tony Ng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c57c8dff8d520f1ca78e5f702a5e2731
https://doi.org/10.7554/elife.73288.sa2
https://doi.org/10.7554/elife.73288.sa2
Autor:
Magnus T. Dillon, Giovanna Alfano, Jose Miguel Vicencio, Shahram Kordasti, Rami Mustapha, Paul R. Barber, Martin Forster, James W. Opzoomer, Kevin J. Harrington, James N. Arnold, Myria Galazi, Gregory Weitsman, Tony Ng, Luigi Dolcetti, Kenrick Ng, Jon Greenberg, Anthony C. C. Coolen, Fabian Flores-Borja, Felix Wong, Jana Doyle
BackgroundAdvanced Head and Neck Squamous Cell Cancer (HNSCC) is associated with a poor prognosis, and biomarkers that predict response to treatment are highly desirable. The primary aim was to predict Progression Free Survival (PFS) with a multivari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e79651a6efe64429ee9f46cd394e9429
https://doi.org/10.1101/2021.09.22.21263942
https://doi.org/10.1101/2021.09.22.21263942
Autor:
Kenrick Ng, Rami Mustapha, Paul R. Barber, Tony Ng, Luigi Dolcetti, Gregory Weitsman, Piers E.M. Patten, Julie Nuo En Chan, Selvam Thavaraj, Jinhai Deng
We propose a novel pipeline for the analysis of imaging mass cytometry data, comparing an unbiased approach, representing the actual gold standard, with a novel biased method. We made use of both synthetic/ controlled datasets as well as two datasets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13aff5178b77ebbff875ece14a0d8614
https://doi.org/10.1101/2021.09.14.460258
https://doi.org/10.1101/2021.09.14.460258
Autor:
Malte von Bonin, Ling Weng, David I. Marks, Giovanna Lombardi, Cristina Trento, Francesco Dazzi, Cara Lomas, Clare L. Bennett, Kim Orchard, Yanira Riffo-Vasquez, Henning Walczak, Krishma Halai, Fiona M. Watt, M Bornhäuser, Laura Barbieri, Luigi Dolcetti, Tik Shing Cheung, Sophie Ward, Antonio Galleu, Jane F. Apperley, Ronjon Chakraverty
Publikováno v:
Galleu, A, Riffo-Vasquez, Y, Trento, C, Lomas, C, Dolcetti, L, Cheung, T S, von Bonin, M, Barbieri, L, Halai, K, Ward, S, Weng, L, Chakraverty, R, Lombardi, G, Watt, F M, Orchard, K, Marks, D I, Apperley, J, Bornhauser, M, Walczak, H, Bennett, C & Dazzi, F 2017, ' Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation ', Science Translational Medicine, vol. 9, no. 416, eaam7828 . https://doi.org/10.1126/scitranslmed.aam7828
The immunosuppressive activity of mesenchymal stromal cells (MSCs) is well documented. However, the therapeutic benefit is completely unpredictable, thus raising concerns about MSC efficacy. One of the affecting factors is the unresolved conundrum th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9fcc24c530da2331d9d19573eb265bb
http://hdl.handle.net/11577/3373014
http://hdl.handle.net/11577/3373014