Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Luigi Di Giamberardino"'
Publikováno v:
Journal of Neurochemistry. 92:1044-1053
The cellular prion protein, PrPc, is a glycosylphosphatidylinositol-anchored cell surface glycoprotein and a protease-resistant conformer of the protein may be the infectious agent in transmissible spongiform encephalopathies. PrPc is localized on gr
Autor:
Christophe Créminon, Kenneth L. Moya, Raymonde Hassig, Luigi Di Giamberardino, Isabelle Laffont
Publikováno v:
Journal of Neurochemistry. 88:155-160
Neuroinvasion of the CNS during orally acquired transmissible spongiform encephalopathies (TSEs) may involve the transport of the infectious agent from the periphery to the CNS via the peripheral nerves. If this occurs within axons, the mechanism of
Autor:
Katia Rodolfo, Martial Ruat, Luigi Di Giamberardino, Nicole Sales, Elisabeth Traiffort, Raymonde Hässig, Kenneth L. Moya, Philippe Frétier
Publikováno v:
European Journal of Neuroscience. 15:1163-1177
PrPc, a sialoglycoprotein present in the normal adult hamster brain, is particularly abundant in plastic brain regions but little is known about the level of expression and the localization of the protein during development. Western blot analysis of
Autor:
Sabina Pappatà, Christian Crouzel, Bertrand Tavitian, Isabelle Doignon, Luigi Di Giamberardino, Antoinette Jobert, G. Blomqvist
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 21:114-131
[11C]physostigmine, an acetylcholinesterase inhibitor, has been shown to be a promising positron emission tomography ligand to quantify the cerebral concentration of the enzyme in animals and humans in vivo. Here, a quantitative and noninvasive metho
Publikováno v:
NeuroReport. 11:1543-1547
The principal aim of this study was to examine the relative contributions from the neuronal and endothelial isoforms of nitric oxide synthase (nNOS and eNOS, respectively) in their capacity to modulate intra-ischemic cerebral blood flow (CBF) changes
Autor:
Christian Crouzel, Antoinette Jobert, Sabina Pappatà, Latchezar Traykov, François Boller, Luigi Di Giamberardino, Françoise Forette, Bertrand Tavitian
Publikováno v:
European Journal of Neurology. 6:273-278
It is unclear whether the palliative effects of tetrahydroaminoacridine (THA) (tacrine, Cognex) on the clinical symptoms of patients affected by Alzheimer's disease (AD) are the result of its inhibitory activity on acetylcholinesterase or on other co
Autor:
Katia Rodolfo, Raymonde Hässig, Kenneth L. Moya, Baptiste Faucheux, Luigi Di Giamberardino, Nicole Sales
Publikováno v:
European Journal of Neuroscience. 10:2464-2471
The presence of an abnormal, protease-resistant form of the prion protein (PrP) is the hallmark of various forms of transmissible spongiform encephalopathies (TSE) which can affect a number of mammalian species, including humans. The normal, cellular
Autor:
Bertrand Tavitian, Antoinette Jobert, Christian Crouzel, Luigi Di Giamberardino, Sophie Bonnot-lours, C. Prenant, Sabina Pappatà
Publikováno v:
European Journal of Pharmacology. 236:229-238
THA (1,2,3,4-tetrahydro-9-amino-acridine, tacrine), a potential therapeutic agent for patients suffering from Alzheimer's disease, has multiple pharmacological sites of action in the brain. In order to study the cerebral binding sites of THA in vivo,
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 12:603-612
The specific activity (SA) of free methionine was measured in plasma and in different regions of the rat brain at 15, 30, or 60 min after intravenous infusion of l-[14C- methyl]methionine. Within these time periods, an apparent steady state of labele
Publikováno v:
Restorative Neurology and Neuroscience. 2:81-88
We studied the modifications occurring in the parent cytoskeleton carried by SCa (the slower of the two slow axonal transport subcomponents) after peripheral nerve crush. The proteins transported in rat sciatic motor axons were radiolabelled by injec