Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Luigi Aloia"'
1
Akademický článek
Epigenetic Regulation of Cell-Fate Changes That Determine Adult Liver Regeneration After Injury
Autor: Luigi Aloia
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The adult liver has excellent regenerative potential following injury. In contrast to other organs of the body that have high cellular turnover during homeostasis (e.g., intestine, stomach, and skin), the adult liver is a slowly self-renewing organ a
Externí odkaz: https://doaj.org/article/02f2ab26c3d4483db5aa9c60353f3b91
Zobrazit plný text záznamu
2
Akademický článek
RYBP and Cbx7 Define Specific Biological Functions of Polycomb Complexes in Mouse Embryonic Stem Cells
Autor: Lluis Morey, Luigi Aloia, Luca Cozzuto, Salvador Aznar Benitah, Luciano Di Croce
Publikováno v: Cell Reports, Vol 3, Iss 1, Pp 60-69 (2013)
The Polycomb repressive complex 1 (PRC1) is required for decisions of stem cell fate. In mouse embryonic stem cells (ESCs), two major variations of PRC1 complex, defined by the mutually exclusive presence of Cbx7 or RYBP, have been identified. Here,
Externí odkaz: https://doaj.org/article/2220ffac54bc460fbf2aee35c62978bd
Zobrazit plný text záznamu
4
The influence of tissue spatial geometry and functional organisation on liver regeneration
Autor: Luigi Aloia
Publikováno v: Seminars in celldevelopmental biology. 130
The adult liver exerts crucial functions, including nutrient metabolism and storage, bile production and drug detoxification. These complex functions expose the liver to constant damage induced by toxins, metabolic intermediates and oxidative stress.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ca5066720231da04e25bd875191ae5
https://pubmed.ncbi.nlm.nih.gov/34563460
Zobrazit plný text záznamu
5
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
Autor: Ary Marsee, Floris J.M. Roos, Monique M.A. Verstegen, Helmuth Gehart, Eelco de Koning, Frédéric Lemaigre, Stuart J. Forbes, Weng Chuan Peng, Meritxell Huch, Takanori Takebe, Ludovic Vallier, Hans Clevers, Luc J.W. van der Laan, Bart Spee, Floris Roos, Monique Verstegen, Stuart Forbes, Luc van der Laan, Sylvia Boj, Pedro Baptista, Kerstin Schneeberger, Carol Soroka, Markus Heim, Sandro Nuciforo, Kenneth Zaret, Yoshimasa Saito, Matthias Lutolf, Vincenzo Cardinale, Ben Simons, Sven van IJzendoorn, Akihide Kamiya, Hiromi Chikada, Shuyong Wang, Seon Ju Mun, Myung Jin Son, Tamer Tevfik Onder, James Boyer, Toshiro Sato, Nikitas Georgakopoulos, Andre Meneses, Laura Broutier, Luke Boulter, Dominic Grün, Jan IJzermans, Benedetta Artegiani, Ruben van Boxtel, Ewart Kuijk, Guido Carpino, Gary Peltz, Jesus Banales, Nancy Man, Luigi Aloia, Nicholas LaRusso, Gregory George, Casey Rimland, George Yeoh, Anne Grappin-Botton, Daniel Stange, Nicole Prior, Janina E.E. Tirnitz-Parker, Emma Andersson, Chiara Braconi, Nicholas Hannan, Wei-Yu Lu, Stephen Strom, Pau Sancho-Bru, Shinichiro Ogawa, Vincenzo Corbo, Madeline Lancaster, Huili Hu, Sabine Fuchs, Delilah Hendriks
Publikováno v: Cell Stem Cell
Cell Stem Cell, 28(5), 816-832. Cell Press
Cell Stem Cell, Vol. 28, no. 5, p. 816-832 (2021)
Cell Stem Cell, 28(5), 816-832. CELL PRESS
Cell Stem Cell, 28(5), 816. Cell Press
Hepatic, pancreatic, and biliary (HPB) organoids are powerful tools for studying development, disease, and regeneration. As organoid research expands, the need for clear definitions and nomenclature describing these systems also grows. To facilitate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2ad5dde6f10e8b90de604b88f3f1ff
Zobrazit plný text záznamu
6
Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration
Autor: Riccardo Aiese Cigliano, German Belenguer, Stuart J. Forbes, Francesco Antonica, Magdalena Zernicka-Goetz, Lucía Cordero-Espinoza, Richard L. Mort, Eric A. Miska, Mikel A. McKie, Niya Aleksieva, Grégoire Vernaz, Andrea H. Brand, Luigi Aloia, Berta Font-Cunill, Meritxell Huch, Jelle van den Ameele, Alexander Raven
Publikováno v: Aloia, L, Mckie, M A, Vernaz, G, Cordero-Espinoza, L, Aleksieva, N, van den Ameele, J, Antonica, F, Font-Cunill, B, Raven, A, Cigliano, R A, Belenguer, G, Mort, R L, Brand, A H, Zernicka-Goetz, M, Forbes, S J, Miska, E A & Huch, M 2019, ' Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration ', Nature Cell Biology, vol. 21, no. 11, pp. 1321–1333 . https://doi.org/10.1038/s41556-019-0402-6
Nat Cell Biol
Following severe or chronic liver injury, adult ductal cells (cholangiocytes) contribute to regeneration by restoring both hepatocytes and cholangiocytes. We recently showed that ductal cells clonally expand as self-renewing liver organoids that reta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413a870a794d22e9273e2f6f9d6b61b3
https://hdl.handle.net/20.500.11820/c82701f6-47e5-4d5e-9793-30a3cd525dd4
Zobrazit plný text záznamu
7
Cellular plasticity in the adult liver and stomach
Autor: Meritxell Huch, Luigi Aloia, Mikel A. McKie
Publikováno v: The Journal of Physiology. 594:4815-4825
Adult tissues maintain function and architecture through robust homeostatic mechanisms mediated by self-renewing cells capable of generating all resident cell types. However, severe injury can challenge the regeneration potential of such a stem/proge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6034264092de3118216fd1c83e1b6af4
https://doi.org/10.1113/jp271769
Zobrazit plný text záznamu
8
RYBP and Cbx7 Define Specific Biological Functions of Polycomb Complexes in Mouse Embryonic Stem Cells
Autor: Luciano Di Croce, Salvador Aznar Benitah, Luigi Aloia, Lluis Morey, Luca Cozzuto
Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Cell Reports, Vol 3, Iss 1, Pp 60-69 (2013)
Cell Reports; Vol 3
The Polycomb repressive complex 1 (PRC1) is required for decisions of stem cell fate. In mouse embryonic stem cells (ESCs), two major variations of PRC1 complex, defined by the mutually exclusive presence of Cbx7 or RYBP, have been identified. Here,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4db71825740650331d1ab2af511441
Zobrazit plný text záznamu
9
Receptor- and Non-Receptor Tyrosine Kinases Induce Processing of the Amyloid Precursor Protein: Role of the Low-Density Lipoprotein Receptor-Related Protein
Autor: Fabiana Passaro, Rosa Marina Melillo, Francesca Carlomagno, Luigi Aloia, Floriana Forzati, Massimo Santoro, Nicola Zambrano, Tommaso Russo, Giuseppina Minopoli
Publikováno v: Neurodegenerative Diseases. 4:94-100
The Alzheimer's beta-amyloid peptides derive from the proteolytic processing of the beta-amyloid precursor protein, APP, by beta- and gamma-secretases. The regulation of this processing is not fully understood. Experimental evidence suggests that the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51b6e2274f862b8e707481a9380ce4d
https://doi.org/10.1159/000101833
Zobrazit plný text záznamu
10
Cellular plasticity in the adult liver and stomach
Autor: Luigi, Aloia, Mikel Alexander, McKie, Meritxell, Huch
Publikováno v: The Journal of physiology. 594(17)
Adult tissues maintain function and architecture through robust homeostatic mechanisms mediated by self‐renewing cells capable of generating all resident cell types. However, severe injury can challenge the regeneration potential of such a stem/pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54ff208eea201e07442b12ff3d700e35
https://pubmed.ncbi.nlm.nih.gov/27028579
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje